部門トップ > 生体分子工学研究グループトップ
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最近の論文発表（2019以降）
2022
- Mie, Y., Okabe, H., Mikami, C., Motomura, T., Matsuda, N. Nanostructured gold thin film electrode derived from surfactant-free gold nanoparticles for enhancement in electrocatalysis. Electrochem. Commun., 16, 107415. DOI:10.1016/j.elecom.2022.107415. (2023).
- Hirano, Y., and Komatsu, Y., Promotion of cytoplasmic localization of oligonucleotides by connecting cross-linked duplexes. RSC Adv., 12, 24471-24477. DOI:10.1039/D2RA04375K. (2022).
- Abdelhady, A. M., Hirano, Y., Onizuka, K., Okamura, H., Komatsu, Y., and Nagatsugi, F., Synthesis of Crosslinked 2′-OMe RNA Duplexes Using 2-Amino-6-Vinylpurine and Their Application for Effective Inhibition of miRNA Function. Current Protocols. 2 e386. DOI:10.1002/cpz1.386. (2022)
2021
- Mie Y., Katagai, S., Mikami, C. Electrochemical Molecular Conversion of α-Keto Acid to Amino Acid at a Low Overpotential Using a Nanoporous Gold Catalyst. Int. J. Mol. Sci., 22, 9442. DOI:10.3390/ijms22179442. (2021).
- Abdelhady, A. M., Hirano, Y., Onizuka, K., Okamura, H., Komatsu, Y., and Nagatsugi, F., Synthesis of crosslinked 2′-OMe RNA duplexes and their application for effective inhibition of miRNA function. Bioorganic and Medicinal Chemistry Letters. 48, 128257. DOI:10.1016/j.bmcl.2021.128257. (2021)
- Khan, N.M.M.U., Arai, T., Tsuda, S., and Kondo, H. : Characterization of microbial antifreeze protein with intermediate activity suggests that a bound-water network is essential for hyperactivity. Scientific Reports 11, 5971. DOI:10.1038/s41598-021-85559-x. (2021).
- Arai T., Yamauchi, A., Miura, A., Kondo, H., Nishimiya Y., Sasaki, Y.C., and Tsuda, S. : Discovery of Hyperactive Antifreeze Protein from Phylogenetically Distant Beetles Questions Its Evolutionary Origin. Int. J. Mol. Sci. 22, 3637. DOI:10.3390/ijms22073637. (2021).
- Okumura, S., Hirano, Y., and Komatsu, Y., Stable duplex-linked antisense targeting miR-148a inhibits breast cancer cell proliferation. SCI REP. 11(1), 11467. doi:10.1038/s41598-021-90972-3 (2021).
2020
- Mie, Y., Katagai, S., Ikegami, M., Electrochemical Oxidation of Monosaccharides at Nanoporous Gold with Controlled Atomic Surface Orientation and Non-Enzymatic Galactose Sensing, Sensors 20 (19), 5632. doi:10.3390/s20195632 (2020).
- Mie, Y., Takayama, H., Hirano, Y., Facile Control of Surface Crystallographic Orientation of Anodized Nanoporous Gold Catalyst and its Application for Highly Efficient Hydrogen Evolution Reaction, J. Catal., 389, 476-482. doi:doi.org/10.1016/j.jcat.2020.06.023 (2020).
- Mie, Y., Takahashi K., Torii R., Jingkai S, Tanaka T, Sueyoshi K, Tsujino H, Yamashita T. Redox State Control of Human Cytoglobin by Direct Electrochemical Method to Investigate its Function in Molecular Basis.Chem. Pharm. Bull., 68, 806-809. doi:10.1248/cpb.c20-00175 (2020).
- Mie, Y., Yasutake, Y., Takayama, H., Tamura, T. Electrochemically boosted cytochrome P450 reaction that efficiently produces 25-hydroxyvitamin D-3. Journal of Catalysis 384, 30-36, doi:10.1016/j.jcat.2020.02.012 (2020).
- Mie, Y., Takahashi, K., Itoga, Y., Sueyoshi, K., Tsujino, H., Yamashita, T. Nanoporous gold based electrodes for electrochemical studies of human neuroglobin. Electrochemistry Communications 110, doi:10.1016/j.elecom.2019.106621 (2020).
- Yamauchi, A., Arai, T., Kondo, H., Sasaki, Y.C., and Tsuda, S. : An ice-binding protein from an Antarctic ascomycete is fine-tuned to bind to specific water molecules located in the prism planes. Biomolecules 10 (5), 759, doi:10.3390/biom10050759 (2020).
- Tsuda, S., Yamauchi, A., Khan, U. N.M.-M., Arai, T., Mahabuddin, S., Miura, A., and Kondo, H.: Fish-derived antifreeze proteins and antifreeze glycoprotein exhibit a different ice-binding property with increasing concentration. Biomolecules 10 (3), 423. doi:10.3390/biom10030423 (2020).
2019
- Arai, T., Nishimiya, Y., Ohyama, Y., Kondo, H., and Tsuda, S. : Calcium-Binding Generates the Semi-Clathrate Waters on a Type II Antifreeze Protein to Adsorb onto an Ice Crystal Surface. Biomolecules, 9, 162. DOI:10.3390/biom9050162. (2019).
- Arai, T., Fukami, D., Hoshino, T., Kondo, H., and Tsuda, S. : Ice‐binding proteins from the fungus Antarctomyces psychrotrophicus possibly originate from two different bacteria through horizontal gene transfer. FEBS J., 286, 946-962. DOI:10.1111/febs.14725. (2019).
- Rahman, A., Arai T., Yamauchi, A., Miura A., Kondo, H., Ohyama, Y., and Tsuda, S. : Ice recrystallization is strongly inhibited when antifreeze proteins bind to multiple ice planes. Sci. Rep., 9, 2212. DOI:10.1038/s41598-018-36546-2. (2019).
- Aohara, T., Furukawa J., Miura, K., Tsuda, S., Poisson J.S., Ben R.N., Wilson P.W., and Satoh S.: Presence of a basic secretory protein in xylem sap and shoots of poplar in winter and its physicochemical activities against winter environmental conditions. J. Plant Res. doi:10.1007/s10265-019-01123-9 (2019).
- Kuramochi, M., Takanashi, C., Yamauchi, A., Doi, M., Mio, K., Tsuda, S., and Sasaki, Y.: Expression of ice-binding proteins in Caenorhabditis elegans improves the survival rate upon cold shock and during freezing. Scientific Reports, 9, 6246, doi:10.1038/s41598-019-42560-8 (2019).
- Ikegami, M., Hirano, Y., Mie, Y. and Komatsu, Y. Adsorptive Stripping Voltammetry for the Determination of Dissolved Oxygen Using a Mesoporous Pt Microelectrode. J. Electrochem. Soc., 166(6) B542-B546 doi:10.1149/2.0021908jes (2019).
- Mie, Y., Yasutake, Y., Ikegami, M. and Tamura, T. Anodized gold surface enables mediator-free and low-overpotential electrochemical oxidation of NADH: A facile method for the development of an NAD(+)-dependent enzyme biosensor. SENSORS AND ACTUATORS B-CHEMICAL, 288, 512-518 doi:10.1016/j.snb.2019.03.039 (2019).
- Yamazaki, A., Nishimiya, Y., Tsuda, S., Togashi, K. and Munehara, H. Freeze tolerance in sculpins (Pisces; Cottoidea) inhabiting north pacific and Arctic oceans: Antifreeze activity and gene sequences of the antifreeze protein. Biomolecules, 9(4), 139 doi:10.3390/biom9040139 (2019).
総説・教科書等
- 小松 康雄, DNA，RNAの末端および内部に対する化学修飾法の開発, 生化学, 82, 12, 1141 -1145 (2010).
- 小松康雄、小島 直, 遺伝子解析にかかわる試薬の開発, Synthesiology, 3, 3, 223-230 (2010).
- 小松 康雄：共有結合型ＤＮＡチップの開発 「新しいＤＮＡチップの科学と応 用」 41-52（2007）.
- Komatsu, Y. and Ohtsuka, E. Regulation of ribozyme activity by oligonucleotides. Methods in Molecular Biology. Vol 252, 165pp, Humana Press, Totowa (2004).
- Komatsu, Y. and Ohtsuka, E. Chemical RNA synthesis (Including RNA with unusual constituents). Comprehensive natural products chemistry Vol 6, 81pp, Pergamon, Oxford (1999).
- 小松康雄：基板表面に固定化させるオリゴヌクレオチドの化学合成 化学と生物44(3): 199-204 (2006).
- 小松 康雄： DNAチップと周辺技術開発. O plus E, 25, 528-532, (2003).
- 小松 康雄、大塚 栄子： ヒト誘導型一酸化窒素合成酵素ｍRNAのRNA酵素による配列特異的切断 血管と内皮, 10, 7-13, (2000).
