Bioimaging Research Group
Research Outline
Target analytes such as biomolecules and biological tissues, or food and environmental substances exist at various scales and concentrations. In order to achieve higher performance imaging and sensing for these targets, we are developing fundamental technologies to enable high-performance imaging and sensing of biomolecules and tissues that exist at various scales and concentrations.
Currently, we are conducting research and development on the following imaging and sensing platforms including devices, materials, and methodologies. In addition, we will actively pursue the social implementation of our outcomes.
Currently, we are conducting research and development on the following imaging and sensing platforms including devices, materials, and methodologies. In addition, we will actively pursue the social implementation of our outcomes.

- Development of a scanning electron-assisted dielectric microscopy (SE-ADM) that enables direct observation of samples in aqueous solutions
- Establishment of technology for quantification of intra-/inter-cellular substances based on fluorescence correlation spectroscopy (FCS)
- Synthetic probe design to visualize the disease-related substances.
- Design of nanocarbon electrode materials that can expand the possibility of electroanalysis


Fig. 1. Experimental set-up of SE-ADM system.
(T. Okada, T. Ogura, Sci. Rep. (2016)

Fig. 2 High-resolution SE-ADM images of osteoblasts.
(T. Iwayama, T. Okada et al., Sci. Adv. (2019))


Development of new detection, quantification and imaging techniques based on optical technology



Some of the reagents were commercialized in collaboration with companies


