日本語
Nano-Biodevice
Research Group
Research Outline
To capture subtle changes in molecules and cells, we develop new analytical technologies by designing what and how to measure from the ground up, based on analytical chemistry. By deciphering the “states” of complex samples, ranging from biomolecules and cells to bacteria, biological fluids, and foods, we contribute to solving challenges in medicine and healthcare.
Research Introduction
The Nano-Biodevice Research Group aims to develop innovative bioanalytical technologies that address challenges in medicine and healthcare, with a core focus on advanced bio-recognition.
By integrating expertise in organic chemistry, polymer chemistry, electrochemistry, surface chemistry, device engineering, and data science, we pursue a comprehensive approach encompassing:
- the design of highly sensitive and selective molecular probes
- the development of measurement platforms compatible with diverse detection modes
- the analysis of complex data using multivariate statistics and machine learning
Through close collaboration among members with diverse expertise, we develop sensing solutions that function effectively with real-world biological samples. Our technologies target applications such as rapid detection of biomolecules, design and quality assessment of pharmaceuticals, and monitoring of biological states in biofluids, cultured cells, and microbiota—ultimately contributing to the advancement of diagnostics, drug discovery, and life science research.
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Members
TOMITA Shunsuke, Ph.D.
- Position
- Group Leader
- Location
- AIST Tsukuba Central 6
- Research Profiles
- Research Theme
-
- Design of fluorescent probe libraries for biosample analysis
- Development of screening technologies based on multivariate data
- Development of analytical technologies for biological liquid-liquid phase separation
KOJIMA Naoshi, Ph.D.
- Position
- Senior Researcher
- Location
- AIST Tsukuba Central 6
- Research Profiles
- Research Theme
-
- Development of simple measurement technology for the K-value freshness indicator in fresh seafood
- Development of novel gene detection technology using bioluminescence
- Research and development of novel nucleic acid therapeutics using chemical modification
MINAMIKI Tsukuru, Ph.D.
- Position
- Senior Researcher
- Location
- AIST Tsukuba Central 6
- Research Profiles
- Research Theme
-
- Development of molecular recognition materials that express functions through organized assembly
- Creation of on-site chemical sensor platforms using molecular assemblies
- Development of comprehensive discrimination technologies for structural analogs and isomers
NISHIHARA Ryo, Ph.D.
- Position
- Principal Collaboration Coordinator, Office for Promotion of Collaboration, Department of Life Science and Biotechnology (Attached to Research Group)
- Location
- AIST Tsukuba Central 1
- Research Profiles
- Research Theme
-
- Design and development of the luminescent substrate luciferin
- Development of bioanalytical technologies utilizing latent enzymatic functions
- Development of luciferase-free luminescence imaging technologies
TAKAHASHI Kanako
- Research Theme
-
- Development of bioanalytical technologies using machine learning
- Creation of microbial analysis methods for medical and healthcare applications
- Construction of multicolor sensing platforms
YAMASHITA Maika, Ph.D.
- Position
- Researcher
- Location
- AIST Tsukuba Central 6
- Research Theme
-
- Development of antibody-drug evaluation technologies using machine learning
- Establishment of protein evaluation methods based on color-development pattern analysis
Research Groups
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