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Year 2026

• T.N.Linh, R.Ootani, H.Watanabe, T.Arimura,* H.Isoda, M.Kawasaki “Divergent self-assembly dynamics of squalene-derived bolaamphiphiles enabled by ethylene glycol–length–switchable Ostwald ripening”RSC Advances, Vol.16, pp.31856–31863（2026）
• Ryo Kuroda, Eisho Toyama, Moe Toyobe, Tomoya Sugai, Maho Imai, Kohei Watanabe, Natsuki Konoue, Katsuya Maruyama, Yuka Furukawa, Masahiro Hayashi, Mio Kondo, Shigeyuki Masaoka, Tsuyoshi Saitoh, Kounosuke Oisaki*, Motomu Kanai* “Electrochemical Tryptophan-Selective Bioconjugation in Neutral Buffer via Cooperative N-Oxyl Radicals” Bioconjugate Chem. 2026, ASAP. DOI: 10.1021/acs.bioconjchem.6c00084
• Tomoya Sugai, Katsuhiko Takeuchi, Kounosuke Oisaki, Norihisa Fukaya, Jun-Chol Choi*, Tsuyoshi Saitoh* “Electrochemical Regeneration of Tetramethyl Orthosilicate from Hexamethoxydisiloxane” ChemElectroChem 2026, 13(1), e202500378. DOI:10.1002/celc.202500378
• Junya Akeno, Kiyosei Takasu, Kounosuke Oisaki, Kanako Nozawa-Kumada, Takeshi Nanjo, Norihisa Fukaya, Yoshihiro Ueda* “Toward N-Linked Glycoproteins: Three-Step Synthesis of Glycan-Asparagine Conjugates from Unprotected Sugars” Org. Lett. 2026, 28(11), 3441-3447. DOI:10.1021/acs.orglett.6c00314
• Tran Ngoc Linh, Rintarou Ootani, Hirohmi Watanabe, Takashi Arimura*, Hiroko Isoda, Masato Kawasaki “Divergent self-assembly dynamics of squalene-derived bolaamphiphiles enabled by ethylene glycol–length–switchable Ostwald ripening” RSC Adv. 2026. in press.
• Tran Ngoc Linh*, Hirohmi Watanabe, Takashi Arimura, Masato Kawasaki “TEM analysis of dicarboxylic acid-induced transition from unilamellar to multilamellar MEL-A vesicles” Nanoscale Horiz. 2026, Advance Article. DOI:10.1039/D6NH00084C
• Koichiro Masuda*, Tetsuya Yamamoto, Takanori Kobayashi, Hidekazu Sano, Ikuo Saito, Aiichiro Nagaki, Akira Yada* “Crystallization-Based Approach to Continuous Manufacturing: A Case Study of Acetaminophen Production” Org. Process Res. Dev. 2026, 30(2), 312-320. DOI:10.1021/acs.oprd.5c00332
• Daisuke Ino*, Satoru Ito, Yoshihiro Kon, Dachao Hong*, Akira Yada, Kazuhiko Sato “Data-driven design of zeolite-TiO2 photocatalysts for sustainable vanillin production” React. Chem. Eng. 2026, 11, 636-645. DOI:10.1039/D5RE00399G
• Yuji Mikata, Saori Yasuda, Poonyawee Suwankeeree, Runo Ozaki, Hideo Konno, Takashi Matsuo, Sunao Shoji “Optimization of bulkiness/dynamicity and pH utilizing N,N′-bis(5,6,7-trimethoxy-2-quinolylmethyl)-N,N′-dialkylethylenediamines as a Cd2+-specific fluorescent sensor” J. Inorg. Biochem. 2026, 276, 113194. DOI:10.1016/j.jinorgbio.2025.113194
• Kengo Ito, Jieun Yoon*, Kazunori Sasaki, Yuri Nakagawa, Hiroyuki Onda, Hiroko Isoda, Tomohiro Okura “Daily intake of cuminaldehyde-rich cumin essential oil improves cognitive function in healthy elderly Japanese adults: a randomized, double-blind, placebo-controlled pilot study” Front Nutr. 2026, 13, 2026. https://doi.org/10.3389/fnut.2026.1784027
• Farhana Ferdousi, Yu Jia Chen, Kazunori Sasaki, Hiroko Isoda* “Feruloyl substitution is associated with distinct neurogenic and metabolic signatures in cinnamoylquinic acid derivatives: An integrated transcriptomic–metabolomic analysis” Biomed Pharmacother. 2026, 198, 119255. https://doi.org/10.1016/j.biopha.2026.119255
• Farhana Ferdousi, Kazunori Sasaki, Toshiaki Nakai, Aiko Niki, Mitsutoshi Nakajima, Hiroko Isoda* “From odorant perception to stress resilience: Transcriptomic insights into olfactory receptor–driven neuromodulation and antidepressant-like effects of linalyl acetate” Biomed Pharmacother. 2026, 199, 119446. https://doi.org/10.1016/j.biopha.2026.119446
• Shotaro Sakka, Satoshi Nitta, Shuya Kandori, Reo Takahashi, Shuhei Suzuki, Kazuki Hamada, Kozaburo Tanuma, Masanobu Shiga, Yoshiyuki Nagumo, Hiromitsu Negoro, Bryan J. Mathis, Farhana Ferdousi, Hiroko Isoda, Takashi Matsuzaka, Hitoshi Shimano, Hiroyuki Nishiyama* “Co-overexpression of ELOVL2 and ELOVL5 promotes clear cell renal cell carcinoma progression through LIMK1-mediated cytoskeletal reorganization” Sci Rep. 2026. https://doi.org/10.1038/s41598-026-55807-z
• 生長幸之助*「逆伸長でペプチド量産 ～コストと廃棄物を削減～」日刊工業新聞（全国版） 2026年2月26日, 31頁.

Year 2025

• Jorge A. Delgado*, Akira Yada, Raphael Wischert, Stephane Streiff “Effects in the performance of bimetallic catalysts for the hydrogenation of amides to amines: From experimental to data-driven insights” Catalysis Today 2025, 460, 115467. DOI:10.1016/j.cattod.2025.115467
• Yoshihito Heike, Asu Takata, Akira Yada, Kanako Nozawa-Kumada, Masaya Sawamura*, Yohei Shimizu* “Phosphorus catalysis enabling α-sp3-C–H amination of 2-alkylpyridines” Org. Chem. Front. 2025, 12, 6059-6069. DOI:10.1039/d5qo00960j
• Kwihwan Kobayashi*, Takenori Kimura, Takuya Tsubaki, Shingo Komatsuzaki, Akira Yada “Continuous Synthesis of Safinamide Mesylate using Flow Reactions, Inline Extraction, and Crystallization” ACS Sustainable Chem. Eng. 2025, 13(36), 15233-15241. DOI:10.1021/acssuschemeng.5c07441
• Munkhzul Ganbold, Shinya Takahashi, Osamu Kakui, Mitsutoshi Nakajima, Hiroko Isoda* “Inhibitory effects of cashew Anacardium occidentale L. kernel, apple, and shell extracts on lipid accumulation and adipogenesis in 3T3-L1 adipocytes” Sci Rep. 2025, 15, 1644. https://doi.org/10.1038/s41598-025-85727-3
• Munkhzul Ganbold, Pakavarin Louphrasitthiphol, Takafumi Miyamoto, Yoshihiro Miyazaki, Tatsuya Oda, Kenichi Tominaga, Hiroko Isoda* “Isorhamnetin exerts anti-proliferative effect on cancer-associated fibroblasts by inducing cell cycle arrest” Biomed Pharmacother. 2025, 185, 117954. https://doi.org/10.1016/j.biopha.2025.117954
• Juhee Cho, Meriem Bejaoui, Hiroko Isoda* “Regulation of Keratinocyte Proliferation and Differentiation by Secoiridoid Oleacein in Monoculture and Fibroblast Co-Culture Models” Biomed Pharmacother. 2025, 185, 117985.https://doi.org/10.1016/j.biopha.2025.117985
• Yu Jia Chen, Farhana Ferdousi, Kazunori Sasaki, Aprill Kee Oliva Mizushima, Hiroko Isoda* “Whole transcriptomic analysis reveals structure-activity relationships of cinnamoylquinic acid derivatives in human amniotic stem cells” Biochem Pharmacol. 2025, 239, 117029. https://doi.org/10.1016/j.bcp.2025.117029
• Elda Nurafnie Ibnu Rasid, Farhana Ferdousi, Kazunori Sasaki, Kyoko Toda, Shinya Takahashi, Mari Maeda-Yamamoto, Hiroko Isoda* “Exploring the Potential of Tsuruazuki Bean as a Functional Food to Curb Obesity Using Human Amniotic Epithelial Cells and 3T3‐L1 Preadipocytes” Food Front. 2025, 6(5), 2359-2375. https://doi.org/10.1002/fft2.70070
• Rui Wang, Munkhzul Ganbold, Farhana Ferdousi, Hiroko Isoda* “Comparative transcriptomic and molecular interaction analysis of olive polyphenols: Unraveling their mechanisms in immune regulation and metabolic processes in adipocytes” Comput Biol Med. 2025, 194, 110507. https://doi.org/10.1016/j.compbiomed.2025.110507
• Oliva Mizushima Aprill Kee, Meryem Bouhoute, Meriem Bejaoui, Farhana Ferdousi, Mitsutoshi Nakajima, Hiroko Isoda* “Pentacyclic triterpenoid Maslinic Acid Promotes Hair Growth Comparable to Minoxidil: A New Insight on the Potential Involvement of Cilia Activity” ACS Pharmacol. Transl. Sci. 2025, 8(8), 2586-2599. https://doi.org/10.1021/acsptsci.5c00189
• Keisuke Sano, Masanobu Shiga, Farhana Ferdousi, Hiromichi Sakurai, Kazuki Hamada, Kozaburo Tanuma, Satoshi Nitta, Yoshiyuki Nagumo, Shuya Kandori, Akio Hoshi, Hiromitsu Negoro, Bryan J. Mathis, Jun Miyazaki, Tran Ngoc Linh, Takashi Arimura, Hiroko Isoda, Hiroyuki Nishiyama* “A novel, synthesized, amphiphilic ethylene glycol squalene derivative suppresses BBN-induced bladder carcinogenesis” Sci Rep. 2025, 15, 30751. https://doi.org/10.1038/s41598-025-16225-9
• Sharmin Aktar, Ayumi Kato, Kyoko Toda, Shinya Takahashi, Mari Maeda-Yamamoto, Farhana Ferdousi, Hiroko Isoda* “Biochemical and mechanistic insights into the potential anti-neuroinflammatory and neuroprotective effect of Zombi pea (Vigna vexillata (L.) A. Rich.) by regulating NF-κB and PI3K-Akt signaling pathways” Food Biosci. 2025, 74, 107917. https://doi.org/10.1016/j.fbio.2025.107917
• Hongyu Lin, Kazunori Sasaki, Farhana Ferdousi, Shinji Kondo, Hiroko Isoda* “A novel synthetic 3,4,5-tri-Feruloylquinic acid enhances learning and memory via neurotrophin signaling in an aging model senescence-accelerated prone 8 mice” Geroscience 2025, 48(2), 2563-2586. https://doi.org/10.1007/s11357-025-01783-7
• Jun Ong, Qingqing Wu, Kazunori Sasaki, Hiroko Isoda, Francis G. Szele* “Nutraceuticals: using food to enhance brain health by modulating postnatal neurogenesis in animal models and patient populations” Stem Cells Transl Med. 2025, 14(5), szaf006. https://doi.org/10.1093/stcltm/szaf006
• Jun Ong, Kazunori Sasaki, Farhana Ferdousi, Megalakshmi Suresh, Hiroko Isoda, Francis G. Szele* “Senescence Accelerated Mouse-Prone 8: a Model of Neuroinflammation and Aging with Features of Sporadic Alzheimer’s disease” Stem Cells 2025, 43(2), sxae091. https://doi.org/10.1093/stmcls/sxae091
• Seiya Ishizawa, Koki Fujimura, Kounosuke Oisaki, Shin-ichi Sato, Jun Ohata* “Catalysis in Chemical Modification of Proteins” ChemCatChem 2025, 17(11), e202402125. DOI:10.1002/cctc.202402125
• Abhishek K. Tiwatane, Prakash Y. Khandave, Sampada Sharad Kulkarni, Kounosuke Oisaki*, Abhay H. Pande* “Chemotherapeutic Drug—Antibody Conjugates (ChemoBodies): Recent Advances and Future Directions” Curr. Oncol. Rep. 2025, 27(11), 1287-1311. DOI:10.1007/s11912-025-01713-y

Year 2024

• Tarojiro Matsumura*, Tomoko Takahashi, Kenji Nagata, Yasunobu Ando, Akira Yada, Blair Thornton, Tatsu Kuwatani “High-Throughput Calibration-Free Laser-Induced Breakdown Spectroscopy” ACS Earth Space Chem. 2024, 8(6), 1259-1271. DOI:10.1021/acsearthspacechem.4c00067
• Kazunori Sasaki, Oliva Aprill Kee, Hiroko Isoda* “Hair Growth-Promoting effect of the coffee bean residue extract on hair follicle dermal papilla cells via the activation of autophagy” J Funct Foods. 2024, 118, 106251. https://doi.org/10.1016/j.jff.2024.106251
• Lin Hongyu, Kazunori Sasaki, Farhana Ferdousi, Hiroko Isoda* “Comparison of Neurogenesis Promotion Effects between Cinnamoylquinic Acids in Neural Stem Cells from Adult Mice Brains” ACS Chem Neurosci. 2024, 15(20), 3713-3723. https://doi.org/10.1021/acschemneuro.4c00329
• Kazunori Sasaki, Jemima Becker, Jun Ong, Sabina Ciaghi, Lynn S. Guldin, Sofia Savastano, Satoshi Fukumitsu, Hidetoshi Kuwata, Francis G. Szele*, Hiroko Isoda* “Rosemary extract activates oligodendrogenesis genes in mouse brain and improves learning and memory ability” Biomed Pharmacother. 2024, 179, 117350. https://doi.org/10.1016/j.biopha.2024.117350
• Daiki Wakasugi, Shinji Kondo, Farhana Ferdousi, Seiya Mizuno, Akira Yada, Kenichi Tominaga, Satoru Takahashi, Hiroko Isoda* “A rare olive compound oleacein functions as a TrkB agonist and mitigates neuroinflammation both in vitro and in vivo” Cell Commun Signal. 2024, 22, 309. https://doi.org/10.1186/s12964-024-01691-x
• Meriem Bejaoui, Aprill Kee Oliva Mizushima, Tran Ngoc Linh, Takashi Arimura, Kenichi Tominaga, Hiroko Isoda* “Triethylene Glycol Squalene Improves Hair Regeneration by Maintaining the Inductive Capacity of Human Dermal Papilla Cells and Preventing Premature Aging” ACS Pharmacol Transl Sci. 2024, 7(7), 2006-2022. https://doi.org/10.1021/acsptsci.4c00114
• Yaman Zhang, Meriem Bejaoui, Tran Ngoc Linh, Takashi Arimura, Hiroko Isoda* “A Novel Amphiphilic Squalene-based Compound with Open-chain Polyethers Reduces Malignant Melanoma Metastasis In-vitro and In-vivo” Cell Commun Signal. 2024, 22, 437. https://doi.org/10.1186/s12964-024-01813-5
• Sharmin Aktar, Ayumi Kato, Kyoko Toda, Shinya Takahashi, Mari Maeda-Yamamoto, Farhana Ferdousi, Hiroko Isoda* “Transcriptomic evidence of black soybean ethanolic extract and 2-aminobutyric acid in suppressing neuroinflammation and enhancing synaptic transmission” Biomed Pharmacother. 2024, 181, 117633. https://doi.org/10.1016/j.biopha.2024.117633
• Yu Cheng, Farhana Ferdousi, Bryan Angelo Foronda, Tran Ngoc Linh, Munkhzul Ganbold, Akira Yada, Takashi Arimura, Hiroko Isoda “A comparative transcriptomics analysis reveals ethylene glycol derivatives of squalene ameliorate excessive lipogenesis and inflammatory response in 3T3-L1 preadipocytes” Heliyon 2024, 10(5), 26867. DOI: https://doi.org/10.1016/j.heliyon.2024.e26867

Year 2023

• Jieun Yoon, Kazunori Sasaki, Korin Tateoka, Tetsuaki Arai, Hiroko Isoda, Tomohiro Okura “Evaluation of Cognitive and Physical Function Among Older Adults by Their Physical Activity: A Cross-Sectional Kasama Study, Japan” J. Alzheimers Dis. 2023, 96(4), 1801-1812. DOI:10.3233/JAD-230675
• Yu Jia Chen, Farhana Ferdousi, Meriem Bejaoui, Kazunori Sasaki, Hiroko Isoda* “Microarray meta-analysis reveals comprehensive effects of 3,4,5-tricaffeolyquinic acid in cell differentiation and signaling” Eur. J. Pharmacol. 2023, 960, 176143.
• Shinji Kondo, Farhana Ferdousi, Jinchang Zhao, Sofya Suidasari, Miki Yokozawa, Ken Yamauchi, Ken-Ichi Tominaga, Hiroko Isoda* “Hematinic Potential of Olive Leaf Extract: Evidence from an In Vivo Study in Mice and a Pilot Study in Healthy Human Volunteers” Nutrients 2023, 15(19), 4095. DOI:10.3390/nu15194095
• Michitaka Fujiwara, Farhana Ferdousi, Hiroko Isoda* “Investigation into Molecular Brain Aging in Senescence-Accelerated Mouse (SAM) Model Employing Whole Transcriptomic Analysis in Search of Potential Molecular Targets for Therapeutic Interventions” Int. J. Mol. Sci. 2023, 24(18), 13867. DOI:10.3390/ijms241813867
• Noamane Taarji, Meryem Bouhoute, Lorena de Oliveira Felipe, Mansour Sobeh, Isao Kobayashi, Marcos A. Neves, Kenichi Tominaga, Hiroko Isoda, Mitsutoshi Nakajima “Self-stabilizing performance of γ-oryzanol in oil-in-water emulsions and solid dispersions” Heliyon 2023, 9(9), e19677. DOI:10.1016/j.heliyon.2023.e19677
• Aicha Laouani, Hana Nasrallah, Awatef Sassi, Farhana Ferdousi, Feten Zar Kalai, Yosra Hasni, Khalifa Limem, Hiroko Isoda*, Saad Saguem* “Exploring the Effects of Short-Term Daily Intake of Nitraria retusa Tea on Lipid Profile: A Pre-Post, Uncontrolled Pilot Study in Both Healthy and Overweight/Obese Adults” Nutrients 2023, 15(16), 3649. DOI:10.3390/nu15163649
• Jieun Yoon*, Kazunori Sasaki, Iku Nishimura, Haruna Hashimoto, Tomohiro Okura, Hiroko Isoda* “Effects of Desert Olive Tree Pearls Containing High Hydroxytyrosol Concentrations on the Cognitive Functions of Middle-Aged and Older Adults” Nutrients 2023, 15(14), 3234. DOI:10.3390/nu15143234
• Rui Wang, Munkhzul Ganbold, Farhana Ferdousi, Kenichi Tominaga, Hiroko Isoda* “A Rare Olive Compound Oleacein Improves Lipid and Glucose Metabolism, and Inflammatory Functions: A Comprehensive Whole-Genome Transcriptomics Analysis in Adipocytes Differentiated from Healthy and Diabetic Adipose Stem Cells” Int. J. Mol. Sci. 2023, 24(13), 10419. DOI:10.3390/ijms241310419
• Yasuhiro Shimamoto, Tadahiro Fujitani, Eriko Uchiage, Hiroko Isoda, Ken-Ichi Tominaga* “Solid acid-catalyzed one-step synthesis of oleacein from oleuropein” Sci. Rep. 2023, 13, 8275. DOI:10.1038/s41598-023-35423-x
• Tran Ngoc Linh, Takashi Arimura*, Ken-Ichi Tominaga, Hiroko Isoda, Masato Kawasaki, Naruhiko Adachi “Effect of Alkali Metal Cations on the Unilamellar Vesicle of a Squalene Bearing 18-Crown-6” ACS Omega 2023, 8(12), 11583-11587. DOI:10.1021/acsomega.3c00744
• Toshifumi Tatsumi, Koki Sasamoto, Takuya Matsumoto, Ryo Hirano, Kazuki Oikawa, Masato Nakano, Masaru Yoshida, Kounosuke Oisaki*, Motomu Kanai* “Practical N-to-C peptide synthesis with minimal protecting groups” Commun. Chem. 2023, 6, 231. DOI:10.1038/s42004-023-01030-0
• Katarzyna Joanna Malawska, Shinjiro Takano, Kounosuke Oisaki*, Haruaki Yanagisawa, Masahide Kikkawa, Tatsuya Tsukuda, Motomu Kanai* “Bioconjugation of Au25 Nanocluster to Monoclonal Antibody at Tryptophan” Bioconjugate Chem. 2023, 34(4), 781-788. DOI:10.1021/acs.bioconjchem.3c00069
• 生長幸之助*「計画的偶発性マインドがもたらした研究キャリア」有機合成化学協会誌 2023, 81(4), 366-380. DOI:10.5059/yukigoseikyokaishi.81.366
• 金井求, 生長幸之助, 豊邉萌「レドックス活性を利用した抗体修飾と応用」MEDCHEM NEWS 2023, 33(1), 33-37. DOI:10.14894/medchem.33.1_33

Year 2022

• Kazuhiro Aonuma, DongZhu Xu, Nobuyuki Murakoshi, Kazuko Tajiri, Yuta Okabe, Zixun Yuan, Siqi Li, Yoshiko Murakata, Kenichi Tominaga, Akihiko Nogami, Kazutaka Aonuma, Masaki Ieda, Hiroko Isoda “Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation” Clin. Sci. 2022, 136(24), 1831-1849. DOI:10.1042/CS20220319
• Kengo Iwata, Farhana Ferdousi, Yoshinobu Arai, Hiroko Isoda* “Interactions between Major Bioactive Polyphenols of Sugarcane Top: Effects on Human Neural Stem Cell Differentiation and Astrocytic Maturation” Int. J. Mol. Sci. 2022, 23(23), 15120. DOI:10.3390/ijms232315120
• Kazunori Sasaki, Tran Ngoc Linh, Atsushi Hirano, Kenichi Tominaga, Sachiko Nukaga, Hiroyuki Nozaki, Takashi Arimura, Hiroko Isoda* “Microalgae extract induces antidepressant-like activity via neuroinflammation regulation and enhances the neurotransmitter system” Food Chem. Toxicol. 2022, 170, 113508. DOI:10.1016/j.fct.2022.113508
• 礒田博子, 佐々木一憲, 高橋真哉「微細藻類の生理活性作用」フレグランスジャーナル 2022, 50(9), 10-15.
• Farhana Ferdousi, Kazunori Sasaki, Dongzhu Xu, Yun-Wen Zheng, Francis G. Szele, Hiroko Isoda* “Editorial: Directing Stem Cell Fate Using Plant Extracts and Their Bioactive Compounds” Front. Cell Dev. Biol. 2022, 10, 957601. DOI:10.3389/fcell.2022.957601
• Meriem Bejaoui, Aprill Kee Oliva, May Sin Ke, Farhana Ferdousi, Hiroko Isoda* “3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-caffeoylquinic Acid (TCQA)” Cells 2022, 11(13), 2093. DOI:10.3390/cells11132093
• Masahito Yoshida, Tomoya Matsushita, Shinji Kondo, Hiroko Isoda, Hideo Kigoshi* “Structure Revision of Trichomide D by Total Synthesis” J. Nat. Prod. 2022, 85(7), 1850-1860. DOI:10.1021/acs.jnatprod.2c00440
• 山田敦士, 生田淳也, 山本祥史, 富永健一「非可食バイオマス資源を原料とする化学品製造プロセスの開発」ファインケミカル 2022, 51(6), 39-46.
• Aprill Kee Oliva, Meriem Bejaoui, Atsushi Hirano, Takashi Arimura, Tran Ngoc Linh, Eriko Uchiage, Sachiko Nukaga, Kenichi Tominaga, Hiroyuki Nozaki, Hiroko Isoda* “Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis” Biomedicines 2022, 10(5), 1186. DOI:10.3390/biomedicines10051186
• Farhana Ferdousi, Hiroko Isoda* “Regulating Early Biological Events in Human Amniotic Epithelial Stem Cells Using Natural Bioactive Compounds: Extendable Multidirectional Research Avenues” Front. Cell Dev. Biol. 2022, 10, 865810. DOI:10.3389/fcell.2022.865810
• Kazunori Sasaki, Hiroko Isoda* “Dietary consumption of desert olive tree pearls reduces brain Aβ content and improves learning and memory ability in aged mice” J. Funct. Foods 2022, 91, 105021. DOI:10.1016/j.jff.2022.105021
• 富永健一, 西田まゆみ「CO2を原料とした連続低級アルコール生産技術」クリーンエネルギー 2022, 31(2), 7-13.
• Noamane Taarji, Meryem Bouhoute, Isao Kobayashi, Kenichi Tominaga, Hiroko Isoda, Mitsutoshi Nakajima “Preparation and characterization of concentrated γ-Oryzanol nanodispersions by solvent displacement method: Effect of processing conditions on nanoparticles formation” Food Hydrocoll. 2022, 123, 107161. DOI:10.1016/j.foodhyd.2021.107161
• Naoki Ito, Kazunori Sasaki, Eiji Hirose, Takayuki Nagai, Hiroko Isoda, Hiroshi Odaguchi* “Preventive effect of a Kampo medicine, kososan, on recurrent depression in a mouse model of repeated social defeat stress” Gene 2022, 806, 145920. DOI:10.1016/j.gene.2021.145920
• 清川慎介, 安田大輔, 生長幸之助「新たな機能性分子を合成する手法“クリックケミストリー”―2022年ノーベル化学賞によせて」医学のあゆみ 2022, 283(13), 1173-1175. DOI:10.32118/ayu283131173
• 生長幸之助, 浅野圭佑, 上田善弘「有機触媒探索からの計画的セレンディピティ」医学のあゆみ 2022, 282(9), 826-828. DOI:10.32118/ayu28209826
• Takaaki Tatsuguchi, Takehito Uruno, Yuki Sugiura, Kounosuke Oisaki, Daisuke Takaya, Daiji Sakata, Yoshihiro Izumi, Takaya Togo, Yuko Hattori, Kazufumi Kunimura, Tetsuya Sakurai, Teruki Honma, Takeshi Bamba, Masafumi Nakamura, Motomu Kanai, Makoto Suematsu, Yoshinori Fukui “Pharmacological intervention of cholesterol sulfate-mediated T cell exclusion promotes antitumor immunity” Biochem. Biophys. Res. Commun. 2022, 609, 183-188. DOI:10.1016/j.bbrc.2022.04.035
• Kenta Sakai, Kounosuke Oisaki, Motomu Kanai “A Germanium Catalyst Accelerates the Photoredox α-C(sp3)-H Alkylation of Primary Amines” Org. Lett. 2022, 24(18), 3325-3330.

Year 2021

• Noamane Taarji, Meryem Bouhoute, Youssef Chafai, Abdellatif Hafidi, Isao Kobayashi, Marcos A. Neves, Kenichi Tominaga, Hiroko Isoda, Mitsutoshi Nakajima “Emulsifying Performance of Crude Surface-Active Extracts from Liquorice Root (Glycyrrhiza glabra)” ACS Food Sci. Technol. 2021, 1(8), 1472-1480. DOI:10.1021/acsfoodscitech.1c00208
• Yuki Yamauchi, Farhana Ferdousi, Satoshi Fukumitsu, Hiroko Isoda* “Maslinic Acid Attenuates Denervation-Induced Loss of Skeletal Muscle Mass and Strength” Nutrients 2021, 13(9), 2950. DOI:10.3390/nu13092950
• Ken-ichi Tominaga “Refinery Technology for Cellulosic Biomass by Chemical Approach” Oleoscience 2021, 21(10), 409-415. DOI:10.5650/oleoscience.21.409
• Meriem Bejaoui, Noamane Taarji, Masako Saito, Mitsutoshi Nakajima, Hiroko Isoda* “Argan (Argania spinosa) press cake extract enhances cell proliferation and prevents oxidative stress and inflammation of human dermal papilla cells” J. Dermatol. Sci. 2021, 103(1), 33-40. DOI:10.1016/j.jdermsci.2021.06.003
• Shinji Kondo, Farhana Ferdousi, Ken Yamauchi, Sofya Suidasari, Miki Yokozawa, Mohamed Moncef Harrabi, Ken-ichi Tominaga, Hiroko Isoda* “Comprehensive transcriptome analysis of erythroid differentiation potential of olive leaf in haematopoietic stem cells” J. Cell. Mol. Med. 2021, 25(15), 7229-7243. DOI:10.1111/jcmm.16752
• Shinya Takahashi, Farhana Ferdousi, Yun-Wen Zheng, Tatsuya Oda, Hiroko Isoda* “Human Amniotic Epithelial Cells as a Tool to Investigate the Effects of Cyanidin 3-O-Glucoside on Cell Differentiation” Int. J. Mol. Sci. 2021, 22(7), 3768. DOI:10.3390/ijms22073768
• Firdaous Fainassi, Noamane Taarji*, Fatiha Benkhalti, Abdellatif Hafidi, Marcos A. Neves, Hiroko Isoda, Mitsutoshi Nakajima “Emulsion Formation and Stabilizing Properties of Olive Oil Cake Crude Extracts” Processes 2021, 9(4), 633. DOI:10.3390/pr9040633
• Meriem Bejaoui, Farhana Ferdousi, Yun-Wen Zheng, Tatsuya Oda, Hiroko Isoda* “Regulating cell fate of human amnion epithelial cells using natural compounds: an example of enhanced neural and pigment differentiation by 3,4,5-tri-O-caffeoylquinic acid” Cell Commun. Signal. 2021, 19, 26. DOI:10.1186/s12964-020-00697-5
• Zineb Omari, Kazunori Sasaki, Mouad Sabti, Meriem Bejaoui, Abdellatif Hafidi, Chemseddoha Gadhi, Hiroko Isoda “Dietary administration of cumin-derived cuminaldehyde induce neuroprotective and learning and memory enhancement effects to aging mice” Aging 2021, 13(2), 1671-1685. DOI:10.18632/aging.202516
• Kazunori Sasaki, Noelia Geribaldi-Doldán, Qingqing Wu, Julie Davies, Francis G. Szele*, Hiroko Isoda* “Microalgae Aurantiochytrium sp. Increases Neurogenesis and Improves Spatial Learning and Memory in Senescence-Accelerated Mouse-Prone 8 Mice” Front. Cell Dev. Biol. 2021, 8, 600575. DOI:10.3389/fcell.2020.600575
• Noamane Taarji, Meryem Bouhoute, Hakiki Melanie, Abdellatif Hafidi, Isao Kobayashi, Marcos A. Neves, Kenichi Tominaga, Hiroko Isoda, Mitsutoshi Nakajima “Stability characteristics of O/W emulsions prepared using purified glycyrrhizin or a non-purified glycyrrhizin-rich extract from liquorice root (Glycyrrhiza glabra)” Colloids Surf. A Physicochem. Eng. Asp. 2021, 614, 126006. DOI:10.1016/j.colsurfa.2020.126006

Year 2020

• Shin-ichi Adachi*, Kazunori Sasaki, Shinji Kondo, Wataru Komatsu, Fumiaki Yoshizawa, Hiroko Isoda, Kazumi Yagasaki “Antihyperuricemic Effect of Urolithin A in Cultured Hepatocytes and Model Mice” Molecules 2020, 25(21), 5136. DOI:10.3390/molecules25215136
• 荒木理沙, 佐々木一憲, 恩田浩幸, 中村俊介, 葛西雅博, 金子俊之, 礒田博子, 橋本幸一「ローズマリーエキスの継続摂取による日本人健常成人男性の気分状態や疲労感、認知機能の改善可能性について」応用薬理 2020, 98(5/6), 61-68.
• Kazuhiro Aonuma, Farhana Ferdousi, DongZhu Xu, Kenichi Tominaga, Hiroko Isoda* “Effects of Isorhamnetin in Human Amniotic Epithelial Stem Cells in vitro and Its Cardioprotective Effects in vivo” Front. Cell Dev. Biol. 2020, 8, 578197. DOI:10.3389/fcell.2020.578197
• 荒木理沙, 橋本幸一「玄米と納豆の機能性」食品と容器 2020, 61(9), 532-538.
• Isaac Amoah*, Noamane Taarji, Paa-Nii T. Johnson, Jonathan Barrett, Carolyn Cairncross, Elaine Rush* “Plant-Based Food By-Products: Prospects for Valorisation in Functional Bread Development” Sustainability 2020, 12(18), 7785. DOI:10.3390/su12187785
• Meryem Bouhoute, Noamane Taarji, Lorena de Oliveira Felipe, Youssef Habibi, Isao Kobayashi, Mohammed Zahar, Hiroko Isoda, Mitsutoshi Nakajima, Marcos A. Neves “Microfibrillated cellulose from Argania spinosa shells as sustainable solid particles for O/W Pickering emulsions” Carbohydr. Polym. 2020, 251, 116990. DOI:10.1016/j.carbpol.2020.116990
• Menghua Zhang, Taiki Sunaba, Yiting Sun, Takahiro Shibata, Kazunori Sasaki, Hiroko Isoda, Hideo Kigoshi*, Masaki Kita* “Acyl-CoA dehydrogenase long chain (ACADL) is a target protein of stylissatin A, an anti-inflammatory cyclic heptapeptide” J. Antibiot. 2020, 73, 589-592. DOI:10.1038/s41429-020-0322-5
• Myra O. Villareal, Thanyanan Chaochaiphat, Meriem Bejaoui, Kozo Sato, Hiroko Isoda* “Tara Tannin Regulates Pigmentation by Modulating Melanogenesis Enzymes and Melanosome Transport Proteins Expression” Planta Med. Int. Open 2020, 7(1), e34-e44. DOI:10.1055/a-1141-0151
• Meriem Bejaoui, Myra O. Villareal, Hiroko Isoda* “3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes” Front. Cell Dev. Biol. 2020, 8, 175. DOI:10.3389/fcell.2020.00175
• Risa Araki, Takeshi Yamada, Kazushi Maruo, Akihiro Araki, Rena Miyakawa, Hiroaki Suzuki, Koichi Hashimoto* “Gamma-Polyglutamic Acid-Rich Natto Suppresses Postprandial Blood Glucose Response in the Early Phase after Meals: A Randomized Crossover Study” Nutrients 2020, 12(8), 2374. DOI:10.3390/nu12082374
• 富永健一「化学プロセスによるCO2資源化の世界動向」湯川英明監修『脱石油に向けたCO2資源化技術：化学・生物プロセスを中心に』シーエムシー出版, 2020, 3-9.
• Naoki Ito, Kazunori Sasaki, Hiroaki Takemoto, Yoshinori Kobayashi, Hiroko Isoda, Hiroshi Odaguchi* “Emotional Impairments and Neuroinflammation are Induced in Male Mice Invulnerable to Repeated Social Defeat Stress” Neuroscience 2020, 443, 148-159.
• Risa Araki, Kazunori Sasaki, Hiroyuki Onda, Syunsuke Nakamura, Masahiro Kassai, Toshiyuki Kaneko, Hiroko Isoda, Koichi Hashimoto* “Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial” Nutrients 2020, 12(11), 3551. DOI:10.3390/nu12113551
• Yoshiaki Uchida, Farhana Ferdousi, Yun-Wen Zheng, Tatsuya Oda, Hiroko Isoda* “Global Gene Expression Profiling Reveals Isorhamnetin Induces Hepatic-Lineage Specific Differentiation in Human Amniotic Epithelial Cells” Front. Cell Dev. Biol. 2020, 8, 578036. DOI:10.3389/fcell.2020.578036
• Munkhzul Ganbold, Farhana Ferdousi, Takashi Arimura, Kenichi Tominaga, Hiroko Isoda* “New Amphiphilic Squalene Derivative Improves Metabolism of Adipocytes Differentiated From Diabetic Adipose-Derived Stem Cells and Prevents Excessive Lipogenesis” Front. Cell Dev. Biol. 2020, 8, 577259. DOI:10.3389/fcell.2020.577259
• Kengo Iwata, Qingqing Wu, Farhana Ferdousi, Kazunori Sasaki, Kenichi Tominaga, Haruhisa Uchida, Yoshinobu Arai, Francis G. Szele*, Hiroko Isoda* “Sugarcane (Saccharum officinarum L.) Top Extract Ameliorates Cognitive Decline in Senescence Model SAMP8 Mice: Modulation of Neural Development and Energy Metabolism” Front. Cell Dev. Biol. 2020, 8, 573487. DOI:10.3389/fcell.2020.573487
• Farhana Ferdousi, Shinji Kondo, Kazunori Sasaki, Yoshiaki Uchida, Nobuhiro Ohkohchi, Yun-Wen Zheng, Hiroko Isoda* “Microarray analysis of verbenalin-treated human amniotic epithelial cells reveals therapeutic potential for Alzheimer’s Disease” Aging 2020, 12(6), 5516-5538. DOI:10.18632/aging.102985
• Noamane Taarji, Sekove Vodo, Meryem Bouhoute, Nauman Khalid, Abdellatif Hafidi, Isao Kobayashi, Marcos A. Neves, Hiroko Isoda, Mitsutoshi Nakajima “Preparation of monodisperse O/W emulsions using a crude surface-active extract from argan by-products in microchannel emulsification” Colloids Surf. A Physicochem. Eng. Asp. 2020, 585, 124050. DOI:10.1016/j.colsurfa.2019.124050
• Kazunori Sasaki, Yuka Inami, Kenichi Tominaga, Hideo Kigoshi, Takashi Arimura, Hiroko Isoda “Synthesis of 2-(2-Hydroxyethoxy)-3-hydroxysqualene and Characterization of Its Anti-Inflammatory Effects” BioMed Res. Int. 2020, 2020, 9584567.

Year 2019

• Munkhzul Ganbold, Yasuhiro Shimamoto, Farhana Ferdousi, Kenichi Tominaga, Hiroko Isoda* “Antifibrotic effect of methylated quercetin derivatives on TGFβ-induced hepatic stellate cells” Biochem. Biophys. Rep. 2019, 20, 100678. DOI:10.1016/j.bbrep.2019.100678
• Munkhzul Ganbold, Yohei Owada, Yusuke Ozawa, Yasuhiro Shimamoto, Farhana Ferdousi, Kenichi Tominaga, Yun-Wen Zheng, Nobuhiro Ohkohchi, Hiroko Isoda* “Isorhamnetin Alleviates Steatosis and Fibrosis in Mice with Nonalcoholic Steatohepatitis” Sci. Rep. 2019, 9, 16210. DOI:10.1038/s41598-019-52736-y