Katayama S, Watanabe M, Kato Y, Nomura W, Yamamoto T:
Engineering of Zinc Finger Nucleases Through Structural Modeling Improves Genome Editing Efficiency in Cells.
Adv. Sci.,in press.
Nakamichi Y, Kobayashi J, Toyoda K, Suda M, Hiraga K, Inui M, Watanabe M:
Structural basis for allosteric pathway of 4-amino-4-deoxychorismate synthase.
Acta Cryst D, 79(10):895-908. doi: 10.1107/S2059798323006320.
Kato J, Matsuo T, Takemura K, Kato S, Fujii T, Wada K, Nakamichi Y, Watanabe M, Aoi Y, Morita T, Murakami K, and Nakashimada, Y: Isopropanol production via the thermophilic bioconversion of sugars and syngas using metabolically engineered Moorella thermoacetica. Biotechnol. Biofuels Bioprod., 17, 13.
Tsuboi S, Hoshino YT, Yamamoto-Tamura K, Uenishi H, Omae N, Morita T, Sameshima-Yamashita Y, Kitamoto H, Kishimoto-Mo A:
Enhanced biodegradable polyester film degradation in soil by sequential cooperation of yeast-derived esterase and microbial community.
Environ Sci Pollut Res Int, doi: 10.1007/s11356-024-31994-y. Online ahead of print.
Rini DM, Nakamichi Y, Morita T, Inoue H, Mizukami Y, Yamamoto Y, Suzuki T:
Xylobiose treatment strengthens intestinal barrier function by regulating claudin 2 and heat shock protein 27 expression in human Caco-2 cells.
J Sci Food Agric, doi: 10.1002/jsfa.13111. Online ahead of print.
Nakamichi Y, Saika A, Watanabe M, Fujii T, Morita T:
Structural identification of catalytic His158 of PtMAC2p from Pseudozyma tsukubaensis, an acyltransferase involved in mannosylerythritol lipids formation.
Front Bioeng Biotechnol,11:1243595. doi: 10.3389/fbioe.2023.1243595.
Nakamichi Y, Watanabe M, Fujii T, Inoue H, Morita T:
Crystal structure of reducing-end xylose-releasing exoxylanase in subfamily 7 of glycoside hydrolase family 30.
Proteins,91(9):1341-1350. doi: 10.1002/prot.26505.
Takemura K, Kato J, Kato S, Fujii T, Wada K, Iwasaki Y, Aoi Y, Matsushika A, Morita T, Murakami K, Nakashimada Y:
Enhancing acetone production from H2 and CO2 using supplemental electron acceptors in an engineered Moorella thermoacetica.
J Biosci Bioeng,136(1):13-19. doi: 10.1016/j.jbiosc.2023.04.001.
Kobayashi Y, Li Q, Ushimaru K, Hirota M, Morita T, Fukuoka T:
Isolation and characterization of novel naturally occurring sophorolipid glycerides.
Bioresource Technology Reports, 22, 101399.
Ushimaru K, Nakamura T, Fukuoka S, Takahashi K, Sakakibara K, Koga M, Watanabe R, Morita T, Fukuoka T:
Easy and scalable synthesis of a lignosulfonate-derived thermoplastic with
improved thermal and mechanical properties.
Composites Part B, 255, 110628.
Fukunaga T, Watanabe M, Nakamichi Y, Morita T, Higuchi Y, Maekawa H, Takegawa K:
Mechanistic insights into Schizosaccharomyces pombe GT-A family protein
Pvg3 in the biosynthesis of pyruvylated β1,3-galactose of N-linked oligosaccharides.
J Biosci Bioeng, 135(6):423-432. doi: 10.1016/j.jbiosc.2023.03.002.
Matsuzawa T, Watanabe M, Nakamichi Y, Akita H, Yaoi K:
Structural basis for the catalytic mechanism of the glycoside hydrolase
family 3 isoprimeverose-producing oligoxyloglucan hydrolase from Aspergillus
oryzae.
FEBS Lett, 596(15):1944-1954. doi: 10.1002/1873-3468.14427.
Nakamichi Y, Matsuzawa T, Watanabe M, Yaoi K:
Crystal structure of glycoside hydrolase family 31 α-xylosidase from a
soil metagenome.
Biosci Biotechnol Biochem, 86(7):855-864. doi: 10.1093/bbb/zbac058.
Matsuzawa T, Watanabe M, Nakamichi Y, Akita H, Yaoi K:
Crystal structure of metagenomic β-glycosidase MeBglD2 in complex with various saccharides.
Appl Microbiol Biotechnol, 106(12):4539-4551. doi: 10.1007/s00253-022-12018-6.
Matsuzawa T, Watanabe M, Nakamichi Y, Kameyama A, Kojima N, Yaoi K:
Characterization of an extracellular α-xylosidase involved in xyloglucan
degradation in Aspergillus oryzae.
Appl Microbiol Biotechnol, 106(2):675-687. doi: 10.1007/s00253-021-11744-7.
Kondo T, Yasui C, Miyajima I, Banno T, Asakura K, Fukuoka T, Ushimaru K, Koga M, Saika A, Morita T, Takahashi Y, Hayashi C, Igarashi M, Takahashi D, Toshima K:
Synthesis of Mannosylerythritol Lipid Analogues and their Self-Assembling
Properties, Recovery Effects on Damaged Skin Cells, and Antibacterial Activity.
Chemistry, 28(55):e202201733. doi: 10.1002/chem.202201733.
Saika A, Koike H, Yamamoto S, Sugahara T, Kawahara A, Sogabe A, Morita T:
Improvement of Oil Degradation and MEL Production in a Yeast Strain, Pseudozyma tsukubaensis, by Translation Elongation Factor 1 Promoter-driven Expression of a Lipase.
J Oleo Sci, 71(9):1421-1426. doi: 10.5650/jos.ess22089.
Kobayashi S, Kato J, Wada K, Takemura K, Kato S, Fujii T, Iwasaki Y, Aoi Y, Morita T, Matsushika A, Murakami K, Nakashimada Y:
Reversible Hydrogenase Activity Confers Flexibility to Balance Intracellular
Redox in Moorella thermoacetica.
Front Microbiol, 13:897066. doi: 10.3389/fmicb.2022.897066. eCollection 2022.
Kondo T, Yasui C, Banno T, Asakura K, Fukuoka T, Ushimaru K, Koga M, Minamikawa H, Saika A, Morita T, Takahashi D, Toshima K:
Self-Assembling Properties and Recovery Effects on Damaged Skin Cells of
Chemically Synthesized Mannosylerythritol Lipids.
Chembiochem, 23(2):e202100631. doi: 10.1002/cbic.202100631
Wada K, Saika A, Ushimaru K, Sato S, Fukuoka T, Morita T:
Metabolomic Evaluation of the Central Metabolic Pathways of Mannosylerythritol Lipid Biosynthesis in Moesziomyces antarcticus T-34.
J Oleo Sci, 71(1):119-125. doi: 10.5650/jos.ess21229
Ushimaru K, Koga M, Morita T, Fukuoka T:
SAXS-based study of crosslinking homogeneity in bio-based complexes prepared
via the Maillard reaction between cationic polyelectrolytes and fructose.
POLYMER, 251,124929
Wada K, Koike H, Morita T:
Draft Genome Sequence of a Basidiomycetous Yeast, Ustilago shanxiensis
CBS 10075, Which Produces Mannosylerythritol Lipids.
Microbiol Resour Announc, 10(48):e0070621. doi: 10.1128/MRA.00706-21.
Sato S, Ino K, Ushimaru K, Wada K, Saika A, Fukuoka T, Ohshiman K, Morita T:
Evaluating haloarchaeal culture media for ultrahigh-molecular-weight polyhydroxyalkanoate
biosynthesis by Haloferax mediterranei.
Appl Microbiol Biotechnol, 105(18):6679-6689. doi: 10.1007/s00253-021-11508-3.
Fukuoka T, Nakamura S, Morita T, Ohmura T, Kotani M, Naito Y, Sato H:
Surface-assisted Laser Desorption/ionization Mass Spectrometry Analysis of the Glycolipid Biosurfactants, Mannosylerythritol Lipids, Using an Ionization-assisting Substrate.
J Oleo Sci, 70(8):1175-1179. doi: 10.5650/jos.ess21084.
Omae N, Sameshima-Yamashita Y, Ushimaru K, Koike H, Kitamoto H, Morita T:
Disruption of protease A and B orthologous genes in the basidiomycetous
yeast Pseudozyma antarctica GB-4(0) yields a stable extracellular biodegradable
plastic-degrading enzyme.
PLoS One, 16(3):e0247462. doi: 10.1371/journal.pone.0247462. eCollection 2021
Fujii T, Inoue H, Matsushika A:
The Transcription Factor Gene tclB2 Regulates Mannanolytic Enzyme Production
in the Fungus Talaromyces cellulolyticus.
Appl Biochem Biotechnol, 193(10):3163-3172 (2021).
Wada K, Fujii T, Inoue H, Akita H, Morita T, Matsushika A:
Application of a pyruvate-producing Escherichia coli strain LAFCPCPt-accBC-aceE:
a case study for D-lactate production.
Fermentation, 6(3), 70; https://doi.org/10.3390/fermentation6030070.
Matsuzawa T, Kameyama A, Nakamichi Y, Yaoi K:
Identification and characterization of two xyloglucan-specific endo-1,4-glucanases
in Aspergillus oryzae.
Appl Microbiol Biotechnol, 104(20):8761-8773. doi: 10.1007/s00253-020-10883-7.
Nakamichi Y, Fujii T, Watanabe M, Matsushika A, Inoue H:
Crystal structure of GH30-7 endoxylanase C from the filamentous fungus
Talaromyces cellulolyticus.
Acta Crystallogr F Struct Biol Commun, 76(Pt 8):341-349. doi: 10.1107/S2053230X20009024.
Akita H, Nakamichi Y, Morita T, Matsushika A:
Characterization of an NAD(P)+-dependent meso-diaminopimelate dehydrogenase from Thermosyntropha lipolytica.
Biochim Biophys Acta Proteins Proteom, 1868(10):140476 (2020).
Akita H, Fujimoto S, Wada K, Takeda N, Iwasaki Y, Fujii T, Matsushika A:
Performance of Burkholderia multivorans CCA53 for ethyl red degradation.
J Gen Appl Microbiol, 66(4):220-227 (2020).
Akita H, Nakamichi Y, Morita T, Matsushika A:
Identification and functionalcharacterization of NAD(P) + -dependent meso-diaminopimelate dehydrogenase from Numidum massiliense.
Microbiology Open, 9(8):e1059 (2020).
Uechi K, Watanabe M, Fujii T, S, Inoue H:
Identification and biochemicalcharacterization of major β-Mannanase in Talaromyces cellulolyticus mannanolytic system.
Appl Biochem Biotechnol, 192(2):616-631 (2020).
Nakamichi Y, Watanabe M, Matsushika A, Inoue H:
Substrate recognition by a bifunctional GH30‐7 xylanase B from Talaromyces cellulolyticus.
FEBS Open Bio, 10(6), 1180-1189
Wada K, Koike H, Fujii T, Morita T:
Targeted transcriptomic study of the implication of central metabolic pathways
in mannosylerythritol lipids biosynthesis in Pseudozyma antarctica T-34.
PLOS ONE 15(1), e0227295
Fujii T, Matsushika A:
The putative transcription factor gene thaB regulates cellulase and xylanase production at the enzymatic and transcriptional level in the fungus Talaromyces cellulolyticus.
Appl Biochem Biotechnol, 190(4), 1360-1370.
Wada K, Fujii T, Akita H, Matsushika A:
IoGAS1, a GPI-anchored protein derived from Issatchenkia orientalis, confers tolerance of Saccharomcyces cerevisiae to multiple acids.
Appl Biochem Biotechnol, 190(4), 1349-1359.
著書）CO2を固定する化学合成独立栄養微生物のカーボンリサイクルへの応用の範囲と可能性，加藤 純也，中島田 豊，微生物を活用した有用物質の製造技術 第5章1
著書）バイオ界面活性剤の生産技術とその構造、機能，雜賀 あずさ，森田 友岳，福岡徳馬，バイオマス材料の開発と応用 第5章3節
著書）イオン結合を利用したリグニンスルホン酸由来の複合材料の作製とその特性，牛丸 和乗、森田 友岳、福岡 徳馬，バイオマス材料の開発と応用 第3章4節
総説）糖脂質型バイオ界面活性剤の開発と今後の展望，雜賀 あずさ、森田 友岳、福岡 徳馬，科学と工業, 大阪工研協会，96-9，pp.298-305
解説）酵母が生産するバイオ界面活性剤の開発，森田 友岳、雜賀 あずさ，日本醸造協会誌，公益財団法人日本醸造協会
解説）有用物質生産に関連したバイオによるモノづくりについて，森田 友岳、雜賀 あずさ，生物工学100年史，公益社団法人日本生物工学会
Review) Kitamoto D, Fukuoka T, Saika A, Morita T:
Glycolipid Biosurfactants, Mannosylerythritol Lipids: Distinctive Interfacial Properties and Applications in Cosmetic and Personal Care Products.
J Oleo Sci,71(1):1-13. doi: 10.5650/jos.ess21358
解説）機能性バイオ素材の普及・拡大 に資する 応用微生物学的な基礎研究（照井賞 受賞論文），森田 友岳，日本生物工学会誌
解説) イオン相互作用を介するリグニンスルホン酸エラストマーの開発と自己修復特性，牛丸 和乗、森田 友岳、福岡 徳馬，自己修復材料、自己組織化、形状記憶材料の開発と応用事例，第14節，技術情報協会
糸状菌Talaromyces cellulolyticusによる植物バイオマス糖化技術の研究
藤井 達也, 日本農芸化学会（2024年）農芸化学奨励賞受賞者講演
一次生産を担う微生物を応用した資源循環型バイオものづくり
加藤 純也, 農芸化学会中四国支部第67回講演会シンポジウム「22世紀への農芸化学「SDGsのその先へ」」
Keynote) Tailor-made mannosylerythritol lipids
Morita T, Saika A, Fukuoka T, Biosurfactants International Conference 2022, Stuttgart, Germany
バイオ産業の拡大を目指した微生物や酵素の解析技術
藤井 達也、渡邊 真宏，広島大学統合生命科学研究科 シンポジウム2022
担子菌酵母によるバイオ界面活性剤の生産と産業利用
森田 友岳、雜賀 あずさ，日本農芸化学会2021年度大会シンポジウム
世界に広がる酵母の産業利用-テイラーメイドBS（バイオ界面活性剤）への挑戦-
森田 友岳，第23回酵母合同シンポジウム，Web開催
機能性バイオ素材の普及・拡大に資する応用微生物学的な基礎研究（受賞講演）
森田 友岳，生物工学Webシンポジウム2020，Web開催
微生物プロセスを活用したバイオベース化学品・素材の開発
森田 友岳，2020年度第68回研修セミナー
酵母Kluyveromyces marxianusの脂質代謝に関する解析/ 日本学術振興会 科研費（基盤C), 2024.4-2027.3, 藤井 達也、久米 一規
H2をエネルギーとしてリグニンとCO2の同時資化により基礎化学品を合成する微生物開発/ 野田産研 研究助成（持続可能分野） 2024.4-2025.3, 加藤 純也
Bio－Digital Transformation（バイオDX）産学共創拠点/ JST COI-NEXT（広島大学との連携）, 2023～, 渡邊 真宏、森田 友岳、中道 優介
分子動力学シミュレーション・機械学習を組み合わせた新型コロナウイルス進化予測/日本学術振興会 科研費（基盤A), 2022.4-2026.3, 亀田倫史、森田英嗣、中道 優介、齋藤裕、来見田遥一
微生物嫌気性代謝の合成生物学的プラットフォームの構築/ 日本学術振興会 科研費（基盤C), 2022.4-2025.3, 加藤 純也
再生可能エネルギーを活用した有用物質高生産微生物デザイン/JST 未来社会創造事業, 2021-2023，村上 克治、和田 圭介、藤井 達也、森田 友岳、渡邊 真宏、中道 優介
合成ガスからのバイオケミカル原料製造技術の開発/NEDO先導研究プログラム, 2020-2021，村上 克治、松鹿 昭則、片岡 祥、Thuy Thi Hong Nguyen、藤井 達也、森田 友岳、和田 圭介
革新的バイオ素材・高機能品等の機能設計技術及び生産技術開発/SIP 内閣府, 2020-2023，吉田 勝、亀田 倫史、齋藤 裕、渡邊 真宏、山口 有朋、長畑 律子、中村 考志、中道 優介、今野 英雄、富永 健一、川波 肇、池部 仁善
2024年度農芸化学奨励賞, 藤井達也
第56回生物工学奨励賞（斎藤賞）, 森田友岳