国際度量衡局物質量諮問委員会(BIPM/CCQM)の下で各ワーキンググループが計画・実行する国際比較は、NMIJをはじめとした各国の国家計量標準機関(NMI)の校正・測定能力(CMC)を実証するための重要な場となっています。
私たちのグループでは、
- 核酸分析ワーキンググループ(Nucleic Acid Analysis Working Group, NAWG)
- タンパク質分析ワーキンググループ(Protein Analysis Working Group, PAWG)
- 有機分析ワーキンググループ(Organic Analysis Working Group, OAWG)
- 細胞分析ワーキンググループ(Cell Analysis Working Group, CAWG)
の4つのワーキンググループにおいて関連する国際比較に参加しています。
国際比較への参加を通して培った測定技術は、私たちの開発する認証標準物質に精確な値づけ(純度値や濃度値の決定)を行う上での重要な基盤技術となっています。
NAWG
Reference No. | Description | Coordinating Laboratory |
Start date |
---|---|---|---|
CCQM-P54 | DNA primary quantification | LGC | 2004 |
CCQM-P54.1 | DNA quantification (repeat) | LGC | 2006 |
CCQM-P94 | Quantitative Analysis of DNA Methylation | KRISS | 2006 |
CCQM-P94.1 | Quantitative Analysis of DNA Methylation | KRISS | 2008 |
CCQM-P94.2 | Quantitative Analysis of DNA Methylation | KRISS | 2012 |
CCQM-K86.b | Relative quantification of Bt63 in GM rice matrix sample | NIMC / GLHK | 2015 |
CCQM-K86.c | Relative quantification of genomic DNA fragments extracted from high oil matrix (OSR/canola) | NRC/IRMM | 2016 |
CCQM-P184 | Copy number concentration and fractional abundance of a mutation (SNV or INDEL) mixed with WT DNA | NMIA/LGC | 2017 |
CCQM-P199 | Copy number concentration of HIV-1 RNA genomic sequences | LGC /(NIBSC) | 2018 |
CCQM-P199.b | Copy number concentration of SARS-CoV-2 RNA genomic sequences | NML(LGC), NIMC, NIBSC, NIST | 2020 |
CCQM-K181/P227 | SARS-CoV-2 RNA copy number quantification | LGC, NIMC, NIBSC, NIST | 2022 |
PAWG
Reference No. | Description | Coordinating Laboratory |
Start date |
---|---|---|---|
CCQM-P55 | Peptide / protein quantification | LGC | 2004 |
CCQM-P58 | Fluorescence in ELISA | NPL/NIST | 2004/2005 |
CCQM-P55.1 | Peptide / protein quantification (repeat) | LGC | 2008 |
CCQM-K115 | Peptide purity determination - synthetic human C peptide (HCP) | BIPM/NIMC | 2013 |
CCQM-K151 | Determination of the amount content of a purity-assessed recombinant protein in an aqueous calibration solution | KRISS | 2017 |
CCQM-P164 | Mass fracton of human growth hormone in serum | PTB | 2017 |
CCQM-K115.b | Peptide purity - synthetic oxytocin (OXT) | BIPM/NIMC | 2018 |
CCQM-K115.c | Peptide purity - synthetic glycated hexapeptide of HbA1c (GE) | BIPM/NIMC/HSA | 2019 |
CCQM-K115.2018 | Peptide purity - synthetic hexapeptide of HbA0 (VE) | BIPM/NIMC/HSA | 2019 |
CCQM-P216 | Quantification of SARS-CoV-2 monoclonal antibody in solution | NIM, NRC and BIPM | 2020 |
CCQM-K177 | Determination of Growth hormone in serum using isotope dilution mass spectrometry | PTB | 2021 |
OAWG
Reference No. | Description | Coordinating Laboratory |
Start date |
---|---|---|---|
CCQM-K11.1 | Glucose in Serum (subsequent comparison) | KRISS | 2005 |
CCQM-P77.a | Progesterone in Serum | NIST | 2006 |
CCQM-K63.a | Non-Peptide Hormones in Serum: Cortisol | NIST | 2007-2008 |
CCQM-K63.b | Non-Peptide Hormones in Serum: Progesterone | NIST | 2007-2008 |
CCQM-K11.2 | Glucose in Serum (subsequent comparison) | NIST | 2012 |
CCQM-K12.2 | Creatinine in Serum (subsequent comparison) | NIST | 2012 |
CCQM-K109 | Urea and uric acid in serum | HSA | 2016 |
CCQM-K159 | Mass fraction of leucine, phenylalanine in pooled frozen human plasma | LGC | 2019 |
CAWG
Reference No. | Description | Coordinating Laboratory |
Start date |
---|---|---|---|
CCQM-P222 | Particle number concentration measurement for cellular analysis | NMIJ | 2022 |