To ensure reliable chemical analysis in testing and inspection, we develop and advance inorganic measurement techniques and provide high‑purity inorganic reference materials and composition reference materials for materials, environmental, and food analysis.

We develop, maintain, and supply primary reference materials for metal/non‑metal elemental standard solutions and pH standard solutions in Japan. We also advance primary and equivalent measurement methods and support technical assessment for domestic accredited providers.

We develop and supply a wide range of SI‑traceable standard gases and humidity standards—from trace moisture at the ppb level to high humidity up to a 95°C dew point. We also develop high‑accuracy preparation and calibration techniques that underpin these standards.

To support quality control and environmental risk assessment, we develop reference materials and related measurement technologies for organic composition and moisture, including pesticides, PCBs, PAHs, PFAS, and other target compounds.

Many analytical instruments require calibration using reference materials. We develop organic reference materials and establish accurate purity or concentration values using primary and high‑accuracy measurement approaches for instrument calibration.

Biomolecule measurements underpin health monitoring, food analysis, and pharmaceutical quality control. We develop standards, reference materials, and measurement methods for biomolecules ranging from small molecules (e.g., steroid hormones, amino acids) to proteins and nucleic acids.

Advances in nanotechnology have led to the development of line patterns in semiconductor devices, thin films, multilayer structures, and nanomaterials. Consequently, the development and enhancement of nanometrology techniques suitable for these structures have become increasingly important. Our group employs traceable X-ray reflectometry (T-XRR), X-ray photoelectron spectroscopy (XPS), metrological atomic force microscopy (M-AFM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Flow Particle Tracking (FPT) technologies to distribute certified reference materials, provide calibration services, promote international standardization, and collaborate both within and outside the AIST.

We conduct research on particle and polymer metrology. Particles, powders, and polymer materials are used in advanced materials and medical applications and are also present in the environment (e.g., PM2.5). We develop measurement methods and standards for particle size and related properties.

To address heat‑related challenges such as energy efficiency and thermal management in electronics, we develop thermophysical property measurement and evaluation techniques and provide standards that support industry and society.

We research advanced structural evaluation and property measurement technologies that leverage the metrology framework to contribute to manufacturing and materials development. We also generate and curate reliable physical property data and spectra derived from these measurement and evaluation techniques.