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HOME > Topics List > Development of a New Technology for Easily Evaluating Neuronal Activity Using Raman Spectroscopy

Development of a New Technology for Easily Evaluating Neuronal Activity Using Raman Spectroscopy

Yuka Akagi, a researcher in the Stem Cell Biotechnology Research Group, along with Research Group Associate Yasuyuki S Kida and Technical Staff Aya Norimoto, has developed a new method for evaluating neuronal activity. Traditionally, techniques for assessing neuronal activity required fluorescent probes as indicators. In this achievement, a system has been developed that utilizes Raman spectroscopy, a light-based technology that examines molecules within substances, in conjunction with machine learning to quickly and accurately evaluate neuronal activity. This system can assess not only individual neurons but also neuronal population dynamics. The non-invasive, probe-free neuron evaluation system will contribute to quality control of cells for transplantation in regenerative medicine and to the assessment of efficacy and toxicity of new drugs. Moreover, this technology will aid in the development of treatments for neurological diseases and the advancement of neuroscience.

The details of this technology were published in "Molecules" on July 3, 2024.

*For more details, please see the press release below.

research

Press release

Publication

  • Title:Label-Free Assessment of Neuronal Activity Using Raman Micro-Spectroscopy
  • Authors: Yuka Akagi, Aya Norimoto, Teruhisa Kawamura, Yasuyuki S. Kida.
  • Journal: Molecules
  • DOI: 10.3390/molecules29133174

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