The activation mechanism of Atg15, a phospholipase for organelle membranes

In collaboration with the University of Tokyo and Yamagata University, Chie Motono, a senior researcher, and Kenichiro Imai, a research group leader, have revealed the activation mechanism of lipase Atg15 that directly disintegrates organelle membranes, in autophagy.

Publication

• Journal:Cell Reports (in press)
• Title:Atg15 is a vacuolar phospholipase that disintegrates organelle membranes
• Authors:Yasunori Watanabe*, Yurina Iwasaki, Kyoka Sasaki, Chie Motono, Kenichiro Imai and Kuninori Suzuki*
  *Co-corresponding author

• DOI:10.1016/j.celrep.2023.113567