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Discovery of approved drug candidates for COVID-19

Senior Researcher Takatsugu Hirokawa, in collaboration with National Institute of Infectious Diseases, narrowed down the drug candidates for COVID-19 from the existing approved drugs. In silico modeling shows Nelfinavir binds the SARS-CoV-2 main protease consistent with its inhibition of viral replication, whilst Cepharanthine inhibits viral attachment and entry into cells.

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