Publications

Refereed Papers (2021-present)

  1. Namihira M, Inoue N, Watanabe Y, Hayashi T, Murotomi K, Hirayama K, Sato N.
    Combination of 3 probiotics restores attenuated adult neurogenesis in germ-free mice.
    Stem Cells. 2024 Dec 16:sxae077.[PubMed]
  2. Suzuki N, Oota-Ishigaki A, Kaizuka T, Itoh M, Yamazaki M, Natsume R, Abe M, Sakimura K, Mishina M, Hayashi T.
    Limb-clasping response in NMDA receptor palmitoylation-deficient mice.
    Mol Neurobiol. 2024 Nov;61(11):9125-9135.[PubMed]
  3. Shirasawa T, Hirano K, Namihira M, Cobos LCA, Tomoki T.
    Bangle Rhizome Extract Promotes Hippocampal Neurogenesis Associated with Improved Cognitive Functions: A Case Study.
    Biomedical Journal of Scientific & Technological Research 2024 Sep;52(5):44116-44126.
  4. Yang Y, Arai T, Sasaki D, Kuramochi M, Inagaki H, Ohashi S, Sekiguchi H, Mio K, Kubo T, Sasaki YC.
    Real-time tilting and twisting motions of ligand-bound states of α7 nicotinic acetylcholine receptor.
    Eur Biophys J. 2024 Feb;53(1-2):15-25.[PubMed]
  5. Murotomi K, Kagiwada H, Hirano K, Yamamoto S, Numata N, Matsumoto Y, Kaneko H, Namihira M.
    Cyclo-glycylproline attenuates hydrogen peroxide-induced cellular damage mediated by the MDM2-p53 pathway in human neural stem cells.
    J Cell Physiol. 2022 Dec 31.[PubMed]
  6. Oota-Ishigaki A, Takao K, Yamada D, Sekiguchi M, Itoh M, Koshidata Y, Abe M, Natsume R, Kaneko M, Adachi T, Kaizuka T, Suzuki N, Sakimura K, Okuno H, Wada K, Mishina M, Miyakawa T, Hayashi T.
    Prolonged contextual fear memory in AMPA receptor palmitoylation-deficient mice.
    Neuropsychopharmacology. 2022 Nov;47(12):2150-2159.[PubMed]
  7. Hayashi T.
    Membrane lipid rafts are required for AMPA receptor tyrosine phosphorylation.
    Front Synaptic Neurosci. 2022 Oct 31;14:921772.[PubMed]
  8. Sasaki N, Hirano K, Shichi Y, Itakura Y, Ishiwata T, Toyoda M.
    PRC2-dependent regulation of ganglioside expression during dedifferentiation contributes to the proliferation and migration of vascular smooth muscle cells.
    Front Cell Dev Biol. 2022 Oct 13;10:1003349.[PubMed]
  9. Ogawa H, Azuma M, Umeno A, Shimizu M, Murotomi K, Yoshida Y, Nishioka Y, Tsuneyama K.
    Singlet oxygen -derived nerve growth factor exacerbates airway hyperresponsiveness in a mouse model of asthma with mixed inflammation.
    Allergol Int. 2022 Jul;71(3):395-404.[PubMed]
  10. Murotomi K, Tawara H, Sutoh M, Yasunaga M.
    Iron-accumulating splenocytes may exacerbate non-alcoholic steatohepatitis through the production of proinflammatory cytokines and reactive oxygen species.
    Exp Biol Med (Maywood). 2022 May;247(10):848-855.[PubMed]
  11. Sasaki N, Hirano K, Shichi Y, Gomi F, Yoshimura H, Matsushita A, Toyoda M, Ishiwata T.
    Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression.
    Cancers (Basel). 2022 Apr 19;14(9):2055.[PubMed]
  12. Hayashi Y, Kashio S, Murotomi K, Hino S, Kang W, Miyado K, Nakao M, Miura M, Kobayashi S, Namihira M.
    Biosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis.
    Sci Rep. 2022 Apr 4;12(1):5593.[PubMed]
  13. Niu J, Holland SM, Ketschek A, Collura KM, Hesketh NL, Hayashi T, Gallo G, Thomas GM.
    Palmitoylation couples the kinases DLK and JNK3 to facilitate prodegenerative axon-to-soma signaling.
    Sci Signal. 2022 Mar 29;15(727):eabh2674.[PubMed]
  14. Kaneko H, Namihira M, Yamamoto S, Numata N, Hyodo K.
    Oral administration of cyclic glycyl-proline facilitates task learning in a rat stroke model.
    Behav Brain Res. 2022 Jan 24;417:113561.[PubMed]
  15. Alberto-Silva C, Vieira Portaro FC, Kodama RT, Pantaleão HQ, Inagaki H, Nihei KI, Konno K.
    Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp Campsomeriella annulata annulata.
    Toxins (Basel). 2021 Dec 10;13(12):885.[PubMed]
  16. Hayashi T.
    Evolutionarily Established Palmitoylation-Dependent Regulatory Mechanisms of the Vertebrate Glutamatergic Synapse and Diseases Caused by Their Disruption.
    Front Mol Neurosci. 2021 Nov 15;14:796912.[PubMed]
  17. Hagihara H, Shoji H, Otabi H, Toyoda A, Katoh K, Namihira M, Miyakawa T.
    Protein lactylation induced by neural excitation.
    Cell Rep. 2021 Oct 12;37(2):109820.[PubMed]
  18. Iizumi M, Oota-Ishigaki A, Yamashita M, Hayashi T.
    Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice.
    Front Pharmacol. 2021 Aug 18;12:711737.[PubMed]
  19. Kawai T, Hashimoto M, Eguchi N, Nishino JM, Jinno Y, Mori-Kreiner R, Aspåker M, Chiba D, Ohtsuka Y, Kawanabe A, Nishino AS, Okamura Y.
    Heterologous functional expression of ascidian Nav1 channels and close relationship with the evolutionary ancestor of vertebrate Nav channels.
    J Biol Chem. 2021 Jan-Jun;296:100783.[PubMed]
  20. Ogura C, Hirano K, Mizumoto S, Yamada S, Nishihara S.
    Dermatan sulphate promotes neuronal differentiation in mouse and human stem cells.
    J Biochem. 2021 Feb 6;169(1):55-64.[PubMed]
  21. Shigeri Y, Nakata M, Kubota HY, Tomari N, Yamamoto Y, Uegaki K, Haramoto Y, Bumb C, Tanaka Y, Kinumi T, Inagaki H.
    Identification of Novel Proteins in Foam Nests of the Japanese Forest Green Tree Frog, Rhacophorus arboreus.
    Zoolog Sci. 2021 Feb;38(1):8-19.[PubMed]

Refereed Papers & Book Chapters (2016-2020)

  1. Kojima N, Suda T, Fujii S, Hirano K, Namihira M, Kurita R.
    Quantitative analysis of global 5-methyl- and 5-hydroxymethylcytosine in TET1 expressed HEK293T cells.
    Biosens Bioelectron. 2020 Nov 1;167:112472.[PubMed]
  2. Inagaki H, Haramoto Y, Kubota HY, Shigeri Y.
    Complete mitochondrial genome sequence of Japanese forest green tree frog (Rhacophorus arboreus).
    Mitochondrial DNA B Resour. 2020 Sep 16;5(3):3347-3348.[PubMed]
  3. Hirano K, Kubo M, Fukuyama Y, Namihira M.
    Indonesian Ginger (Bangle) Extract Promotes Neurogenesis of Human Neural Stem Cells through WNT Pathway Activation.
    Int J Mol Sci. 2020 Jul 5;21(13):4772.[PubMed]
  4. Ohtsuka Y, Inagaki H.
    In silico identification and functional validation of linear cationic α-helical antimicrobial peptides in the ascidian Ciona intestinalis.
    Sci Rep. 2020 Jul 28;10(1):12619.[PubMed]
  5. Murotomi K, Umeno A, Sugino S, Yoshida Y.
    Quantitative kinetics of intracellular singlet oxygen generation using a fluorescence probe.
    Sci Rep. 2020 Jun 30;10(1):10616.[PubMed]
  6. Umeno A, Sakashita M, Sugino S, Murotomi K, Okuzawa T, Morita N, Tomii K, Tsuchiya Y, Yamasaki K, Horie M, Takahara K, Yoshida Y.
    Comprehensive analysis of PPAR agonist activities of stereo-, regio-, and enantio-isomers of hydroxyoctadecadienoic acids.
    Biosci Rep. 2020 Apr 8. pii: BSR20193767.[PubMed]
  7. Rádis-Baptista G, Dodou HV, Prieto-da-Silva ÁRB, Zaharenko AJ, Kazuma K, Nihei KI, Inagaki H, Mori-Yasumoto K, Konno K.
    Comprehensive analysis of peptides and low molecular weight components of the giant ant Dinoponera quadriceps venom.
    Biol Chem. 2020 Mar 26. pii: /j/bchm.ahead-of-print/hsz-2019-0397/hsz-2019-0397.xml.[PubMed]
  8. Sasaki N, Gomi F, Hasegawa F, Hirano K, Fujiwara M, Toyoda M, Ishiwata T.
    Characterization of the metastatic potential of the floating cell component of MIA PaCa-2, a human pancreatic cancer cell line.
    Biochem Biophys Res Commun. 2020 Feb 19;522(4):881-888.[PubMed]
  9. Sasaki N, Itakura Y, Gomi F, Hirano K, Toyoda M, Ishiwata T.
    Comparison of functional glycans between cancer stem cells and normal stem cells.
    Histol Histopathol. 2019 Sep;34(9):995-1007.[PubMed]
  10. Nitta KR, Vincentelli R, Jacox E, Cimino A, Ohtsuka Y, Sobral D, Satou Y, Cambillau C, Lemaire P.
    High-Throughput Protein Production Combined with High- Throughput SELEX Identifies an Extensive Atlas of Ciona robusta Transcription Factor DNA-Binding Specificities.
    Methods Mol Biol. 2019;2025:487-517.[PubMed]
  11. Tani N, Kazuma K, Ohtsuka Y, Shigeri Y, Masuko K, Konno K, Inagaki H.
    Mass Spectrometry Analysis and Biological Characterization of the Predatory Ant Odontomachus monticola Venom and Venom Sac Components.
    Toxins (Basel). 2019 Jan 17;11(1). pii: E50.[PubMed]
  12. Murao N, Matsubara S, Matsuda T, Noguchi H, Mutoh T, Mutoh M, Koseki H, Namihira M, Nakashima K.
    Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain.
    Neurosci Res. 2018 May 31. pii: S0168-0102(18)30276-1.[PubMed]
  13. Semi K, Sanosaka T, Namihira M, Nakashima K.
    Nuclear factor I/A coordinates the timing of oligodendrocyte differentiation/maturation via Olig1 promoter methylation.
    HAYATI Journal of Biosciences. 2018 Apr;25(2)
  14. Hirano K, Namihira M
    FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.
    FEBS Open Bio. 2017 Oct 17;7(12):1932-1942.[PubMed]
  15. Kazuma K, Masuko K, Konno K, Inagaki H.
    Combined Venom Gland Transcriptomic and Venom Peptidomic Analysis of the Predatory Ant Odontomachus monticola.
    Toxins (Basel). 2017 Oct 13;9(10). pii: E323.[PubMed]
  16. Kawakami H, Goto SG, Murata K, Matsuda H, Shigeri Y, Imura T, Inagaki H, Shinada T.
    Isolation of biologically active peptides from the venom of Japanese carpenter bee, Xylocopa appendiculata.
    J Venom Anim Toxins Incl Trop Dis. 2017 May 23;23:29.[PubMed]
  17. Inagaki H.
    Snake venom protease inhibitors: enhanced identification, expanding biological function, and promising future.
    In Snakes Venoms (Toxinology), Ed. Gopalakrishnakone, P., Inagaki, H., Mukherjee, A.K., Rahmy, T.R., Vogel, C.-W. Springer. 2017:161-186.
  18. Hirano K, Namihira M.
    New insight into LSD1 function in human cortical neurogenesis.
    Neurogenesis (Austin). 2016 Oct 18;3(1):e1249195. eCollection 2016.[PubMed]
  19. Hirano K, Namihira M.
    LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling The Expression of a Novel Target Gene, HEYL.
    Stem Cells. 2016 Jul;34(7):1872-82. [PubMed]
  20. Noguchi H, Murao N, Kimura A, Matsuda T, Namihira M, Nakashima K.
    DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus.
    J Neurosci. 2016 Jun 1;36(22):6050-68.[PubMed]
  21. Shigeri Y, Horie M, Yoshida T, Hagihara Y, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M.
    Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin.
    J Biochem. 2016 Jan 22. pii: mvw003. [PubMed]
  22. Yamauchi Y, Kimoto H, Yang X, Filkin S, Utkin Y, Kubo T, Inagaki H.
    Pr-SNTX, a short-chain three-finger toxin from Papuan pigmy mulga snake, is an antagonist of muscle-type nicotinic acetylcholine receptor.
    Biosci Biotechnol Biochem. 2016;80(1):158-61.[PubMed]
  • Refereed Papers (2010-2015)
    1. Noguchi, H., Kimura, A., Murao, N., Matsuda, T., Namihira, M., Nakashima, K.
      Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus.
      Neurosci Res. 2015 Jun;95:1-11. [PubMed]
    2. Shigeri Y., Yasuda A., Hagihara Y., Nishi K., Watanabe K., Imura T., Inagaki H., Haramoto Y., Ito Y., Asashima M.
      Identification of novel peptides from amphibian (Xenopus tropicalis) skin by direct tissue MALDI-MS analysis.
      FEBS J. 2015 Jan;282(1):102-13. [PubMed]
    3. Murao, N., Matsuda, T., Noguchi, H., Koseki, H., Namihira, M., Nakashima, K.
      Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells.
      Neurogenesis. 2014; 1:1, e976026.[Taylor & Francis Online]
    4. Ohtsuka, Y., Matsumoto, J., Katsuyama, Y., Okamura, Y.
      Nodal signaling regulates specification of ascidian peripheral neurons through control of the BMP signal.
      Development. 2014 Oct;141(20):3889-99. [PubMed]
    5. Cai W, Naimuddin M, Inagaki H, Kameyama K, Ishida N, Kubo T.
      Directed evolution of three-finger toxin to produce serine protease inhibitors.
      J Recept Signal Transduct Res. 2014 Jun;34(3):154-61. [PubMed]
    6. Urayama, S., Semi, K., Sanosaka, T., Hori, Y., Namihira, M., Kohyama, J., Takizawa, T., Nakashima, K.
      Chromatin accessibility at a STAT3 target site is altered prior to astrocyte differentiation.
      Cell Struct Funct. 2013;38(1):55-66. [PubMed]
    7. Inagaki, H., Kimoto, H., Yamauchi, Y., Kubo, T.
      Functional characterization of Kunitz-type protease inhibitor Pr-mulgins identified from new guinean pseudechis australis.
      Toxicon. 2012 Jan;59(1):74-80. [PubMed]
    8. Inagaki, H., Kubo, T.
      Regional divergence of phospholipase A2-like protein cDNAs between New Guinean and Australian pseudechis australis.
      Toxicon. 2010 Sep 15;56(4):637-9. [PubMed]
    9. Khoueiry, P., Rothbacher, U., Ohtsuka, Y., Daian, F., Frangulian, E., Roure, A., Dubchak, I., Lemaire, P.
      A cis-regulatory signature in ascidians and flies, independent of transcription factor binding sites.
      Curr Biol. 2010 May 11;20(9):792-802. [PubMed]
    10. Matsuda, K., Miura, E., Miyazaki, T., Kakegawa, W., Emi, K., Narumi, S., Fukazawa, Y., Ito-Ishida, A., Kondo, T., Shigemoto, R., Watanabe, M., Yuzaki, M.
      Cbln1 is a ligand for an orphan glutamate receptor delta2, a bidirectional synapse organizer.
      Science. 2010 Apr 16;328(5976):363-8. [PubMed]