"Investigation on endpoints for population-level risk assessment of 4-nonylphenol for medaka based on simulation

Meng Yaobin, —Ρ •jθΣ, “ŒŠC –ΎG, •y‰i εΚ, ’†Ό €Žq

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Population-level risk assessment can employ either abundance or growth rate as endpoint and the linkage between the two was analyzed by simulating the annual behavior of natural Japanese medaka (Oryzias latipes) population under 4-nonylphenol (4-NP) treatment. 

The stochastic annual growth rate, ra and quasi-equilibrium abundances Aeq were simulated when density-dependence was disregarded or considered respectively. With Ricker function of density-dependence, it was found that ra=bSAeq, i.e. density-free growth rate was proportional to equilibrium abundance. 

Such a relationship guaranteed equivalence between the two endpoints for population-level risk assessment and warranted inter-validation when either endpoint was applied.


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simulation, population-level ecological risk assessment 


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