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2023年

Viswan, A; Yoshikawa, C; Yamagishi, A; Furuhata, Y; Kato, Y; Yamazaki, T; Nakamura, C.
Efficient genome editing by controlled release of Cas9 ribonucleoprotein in plant cytosol using polymer-modified microneedle array.
BIOCHEM BIOPHYS RES COMMUN. 2023 Oct 29;686:149179. doi: 10.1016/j.bbrc.2023.149179
Suzuki, S; Saito, S; Narushima, Y; Kodani, S; Kagaya, N; Suenaga, H; Shin-Ya, K; Arai, MA.
Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation.
J ANTIBIOT (Tokyo). 2023 Nov 8. doi: 10.1038/s41429-023-00673-4
Takakuwa, H; Yamazaki, T; Souquere, S; Adachi, S; Yoshino, H; Fujiwara, N; Yamamoto, T; Natsume, T; Nakagawa, S; Pierron, G; Hirose, T.
Shell protein composition specified by the lncRNA NEAT1 domains dictates the formation of paraspeckles as distinct membraneless organelles.
NAT CELL BIOL. 2023 Nov 6. doi: 10.1038/s41556-023-01254-1
Ishii, N; Noguchi, K; Ikemoto, MJ; Yohda, M; Odahara, T.
Optimizing Exosome Preparation Based on Size and Morphology: Insights From Electron Microscopy.
MICROSC MICROANAL. 2023 Oct 13:ozad103. doi: 10.1093/micmic/ozad103
Ishii, N; Odahara, T.
Investigation of the Efficacy of Lanthanoid Heavy Metal Acetates as Electron Staining Reagents for Biomembrane Vesicles.
MICROSC MICROANAL. 2023 Oct 13:ozad107. doi: 10.1093/micmic/ozad107
Takeda, N; Tsuchiya, A; Mito, M; Natsui, K; Natusi, Y; Koseki, Y; Tomiyoshi, K; Yamazaki, F; Yoshida, Y; Abe, H; Sano, M; Kido, T; Yoshioka, Y; Kikuta, J; Itoh, T; Nishimura, K; Ishii, M; Ochiya, T; Miyajima, A; Terai, S.
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis.
INFLAMM REGEN. 2023 Oct 9;43(1):48. doi: 10.1186/s41232-023-00299-x
Ishioka, M; Nihashi, Y; Sunagawa, Y; Umezawa, K; Shimosato, T; Kagami, H; Morimoto, T; Takaya, T.
Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells.
INT J MOL SCI. 2023 Sep 21;24(18):14380. doi: 10.3390/ijms241814380
Miyazawa, K; Penedo, M; Furusho, H; Ichikawa, T; Alam, MS; Miyata, K; Nakamura, C; Fukuma, T.
Nanoendoscopy-AFM for Visualizing Intracellular Nanostructures of Living Cells.
MICROSC MICROANAL. 2023 Jul 22;29(Supplement_1):782. doi: 10.1093/micmic/ozad067.387
Shimazaki, H; Nakamura, K; Ono, A; Segawa, O; Sawakami, K; Koizuka, M; Hirayama, M; Hori, K; Tajima, H; Kuno, A.
Auto-Lectin Dotcoding by Two Octopuses: Rapid Analysis of Fluorescence-Labeled Glycoproteins by an 8-channel Fully-Automatic Bead Array Scanner with a Rolling-Circle Detector.
ANAL CHEM. 2023 Aug 3. doi: 10.1021/acs.analchem.3c01395
Takubo, K; Htun, PW; Ueda, T; Sera, Y; Iwasaki, M; Koizumi, M; Shiroshita, K; Kobayashi, H; Haraguchi, M; Watanuki, S; Honda, ZI; Yamasaki, N; Nakamura-Ishizu, A; Arai, F; Motoyama, N; Hatta, T; Natsume, T; Suda, T; Honda, H.
MBTD1 preserves adult hematopoietic stem cell pool size and function.
PROC NATL ACAD SCI U S A. 2023 Aug 8;120(32):e2206860120. doi: 10.1073/pnas.2206860120
Odaka, H.
Target-Specific O-linked N-acetylglucosamine Modification with a Dual-Specificity Aptamer Reveals Functions of O-GlcNAcylation in beta-catenin.
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY. May 25, 2023; Volume 35(2023) Issue 205. doi: 10.4052/tigg.2309.6E
Ichikawa, T; Alam, MS; Penedo, M; Matsumoto, K; Fujita, S; Miyazawa, K; Furusho, H; Miyata, K; Nakamura, C; Fukuma, T.
Protocol for live imaging of intracellular nanoscale structures using atomic force microscopy with nanoneedle probes.
STAR PROTOC. 2023 Jul 22;4(3):102468. doi: 10.1016/j.xpro.2023.102468
Kumar, V; Dhanjal, JK; Sari, AN; Khurana, M; Kaul, SC; Wadhwa, R; Sundar, D.
Effect of Withaferin-A, Withanone, and Caffeic Acid Phenethyl Ester on DNA Methyltransferases: Potential in Epigenetic Cancer Therapy.
CURR TOP MED CHEM. 2023 Jul 26. doi: 10.2174/1568026623666230726105017
Boottanun, P; Nagai-Okatani, C; Nagai, M; Ungkulpasvich, U; Yamane, S; Yamada, M; Kuno, A.
An improved evanescent fluorescence scanner suitable for high-resolution glycome mapping of formalin-fixed paraffin-embedded tissue sections.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2023 JUL 3. doi: 10.1007/s00216-023-04824-2
Miyashita, K; Yagi, T; Kagaya, N; Takechi, A; Nakata, C; Kanda, R; Nuriya, H; Tanegashima, K; Hoyano, S; Seki, F; Yoshida, C; Hachiro, Y; Higashi, T; Kitada, N; Toya, T; Kobayashi, T; Najima, Y; Goyama, S; Maki, SA; Kitamura, T; Doki, N; Shin-Ya, K; Hara, T.
Identification of compounds that preferentially suppress the growth of T-cell acute lymphoblastic leukemia-derived cells.
CANCER SCI. 2023 Jul 31. doi: 10.1111/cas.15918
Nihashi, Y, Song, X; Yamamoto, M; Setoyama, D; Kida, YS.
Decoding Metabolic Symbiosis between Pancreatic Cancer Cells and Cancer-Associated Fibroblasts Using Cultured Tumor Microenvironment.
INT J MOL SCI. 2023 Jul 3;24(13):11015. doi: 10.3390/ijms241311015
Tanaka, S; Sakaue, H, Koiwai, T; Okuda, N; Okuyama, K; Horioka, Y; Hiramatsu, Y; Kawashima, M; Ishiguro, N; Sato, T.
Near-infrared radiation causes sebaceous gland enlargement along with an ROS-dependent augmentation of epidermal growth factor receptor expression in hamsters.
EXPERIMENTAL DERMATOLOGY. 2023 JUL 4. doi: 10.1111/exd.14878
Fuseya, S; Izumi, H; Hamano, A; Murakami, Y; Suzuki, R; Koiwai, R; Hayashi, T; Kuno, A, Takahashi, S; Kudo, T.
Reduction in disialyl-T antigen levels in mice deficient for both St6galnac3 and St6galnac4 results in blood filling of lymph nodes.
SCI REP. 2023 Jun 29;13(1):10582. doi: 10.1038/s41598-023-37363-y
Taniguchi, M; Okumura, R; Matsuzaki, T; Nakatani, A; Sakaki, K; Okamoto, S; Ishibashi, A; Tani, H; Horikiri, M; Kobayashi, N; Yoshikawa, HY; Motooka, D; Okuzaki, D; Nakamura, S; Kida, T; Kameyama, A, Takeda, K.
Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon.
MUCOSAL IMMUNOL. 2023 Jun 27:S1933-0219(23)00049-1. doi: 10.1016/j.mucimm.2023.06.004
Roberts, MD; McCarthy, JJ; Hornberger, TA; Phillips, SM; Mackey, AL; Nader, GA; Boppart, MD; Kavazis, AN; Reidy, PT; Ogasawara, R, Libardi, CA; Ugrinowitsch, C; Booth, FW; Esser, KA.
Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions.
PHYSIOL REV. 2023 Jun 29. doi: 10.1152/physrev.00039.2022
Fujihara, H; Hirose, J; Suenaga, H.
Evolution of genetic architecture and gene regulation in biphenyl/PCB-degrading bacteria.
FRONTIERS IN MICROBIOLOGY. 2023 Jun 7;14:1168246. doi: 10.3389/fmicb.2023.1168246
Tsuyukubo, A; Morishita, K; Kanamori, T; Sumaru, K.
Construction of a spheroid array culture system on a suspended permeable hydrogel membrane scaffold for improving the expression of a liver-specific drug-metabolizing enzyme of HepG2 cells.
BIOMATER SCI. 2023 Jun 22. doi: 10.1039/d3bm00071k
Ohkawa, M; Konno, M.
RNA Modification Related Diseases and Sensing Methods.
APPLIED SCIENCES-BASEL. 2023 13(11) 6376. doi: 10.3390/app13116376
Zhuang, HT; Fujikura, Y, Ohkura, N; Higo-Yamamoto, S; Mishima, T; Oishi, K.
A ketogenic diet containing medium-chain triglycerides reduces REM sleep duration without significant influence on mouse circadian phenotypes.
FOOD RESEARCH INTERNATIONAL. 2023 Jul;169:112852. doi: 10.1016/j.foodres.2023.112852
Kalra, RS; Chaudhary, A; Omar, A; Li, X; Khurana, M; Kaul, SC, Wadhwa, R.
Stress-induced changes in CARF expression serve as a quantitative predictive measure of cell proliferation fate.
EXP CELL RES. 2023 Jun 3:113669. doi: 10.1016/j.yexcr.2023.113669
Watanabe, T, Tateno, H.
Lectin Blotting of Cell Lysates.
CURR PROTOC. 2023 May;3(5):e790. doi: 10.1002/cpz1.790
Takayama, Y, Akagi, Y, Kida, YS.
Deciphering the Molecular Mechanisms of Autonomic Nervous System Neuron Induction through Integrative Bioinformatics Analysis.
INT J MOL SCI. 2023 May 21;24(10):9053. doi: 10.3390/ijms24109053
Abe, T, Sato, T, Murotomi, K.
Sudachitin and Nobiletin Stimulate Lipolysis via Activation of the cAMP/PKA/HSL Pathway in 3T3-L1 Adipocytes.
FOODS. 2023 May 10;12(10):1947. doi: 10.3390/foods12101947
Kuroda, Y; Oda, T; Shimomura, O; Louphrasitthiphol, P; Mathis, BJ; Tateno, H, Hatano, K.
Novel positron emission tomography imaging targeting cell surface glycans for pancreatic cancer: (18) F-labeled rBC2LCN lectin.
CANCER SCI. 2023 May 19. doi: 10.1111/cas.15846
Sugiyama, JI; Tokunaga, Y; Hishida, M; Tanaka, M; Takeuchi, K; Satoh, D; Imashimizu, M.
Nonthermal acceleration of protein hydration by sub-terahertz irradiation.
NAT COMMUN. 2023 May 22;14(1):2825. doi: 10.1038/s41467-023-38462-0
Odaka, H; Tateno, H.
Single-Cell Glycan and RNA Sequencing (scGR-seq).
CURR PROTOC. 2023 May;3(5):e777. doi: 10.1002/cpz1.777
Arima, K; Akiyama, S; Shin-Ya, K; Matsuda, K; Wakimoto, T.
Carrier Protein Mediated Formation of the Dihydropyridazinone Ring in Actinopyridazinone Biosynthesis.
ANGEW CHEM INT ED ENGL. 2023 May 17:e202305155. doi: 10.1002/anie.202305155
Huifu, H; Shefrin, S; Yang, S; Zhang, Z; Kaul, SC; Sundar, D; Wadhwa, R.
Cucurbitacin-B inhibits cancer cell migration by targeting mortalin and HDM2: computational and in vitro experimental evidence.
J BIOMOL STRUCT DYN. 2023 May 2:1-10. doi: 10.1080/07391102.2023.2206914
Nakagawa, Y; Hishida, T; Sumaru, K; Morishita, K; Kirito, K; Yokojima, S; Sakamoto, Y; Nakamura, S; Uchida, K.
Phototunable Cell Killing by Photochromic Diarylethene of Thiazoyl and Thienyl Derivatives.
JOURNAL OF MEDICINAL CHEMISTRY. 2023, 66 (8) 5937-5949. doi: 10.1021/acs.jmedchem.3c00164
Kumagai, Y; Saito, Y; Kida, YS.
A multiomics atlas of brown adipose tissue development over time.
ENDOCRINOLOGY. 2023 Apr 21:bqad064. doi: 10.1210/endocr/bqad064
Zhang, H; Wang, J; Prakash, J; Zhang, Z; Kaul, SC; Wadhwa, R.
Three-way Cell-based Screening of Antistress Compounds: Identification, Validation, and Relevance to Old-age Related Pathologies.
J GERONTOL A BIOL SCI MED SCI. 2023 Apr 15:glad103. doi: 10.1093/gerona/glad103
Sugiura, T; Hashimoto, K; Kikuta, K; Anazawa, U; Nomura, T; Kameyama, A.
Expression and localisation of MUC1 modified with sialylated core-2 O-glycans in mucoepidermoid carcinoma.
SCI REP. 2023 Apr 8;13(1):5752. doi: 10.1038/s41598-023-32597-2
Ikemoto, MJ; Aihara, Y; Ishii, N; Shigemori, H.
3,4-Dihydroxybenzalacetone Inhibits the Propagation of Hydrogen Peroxide-Induced Oxidative Effect via Secretory Components from SH-SY5Y Cells.
BIOL PHARM BULL. 2023;46(4):599-607. doi: 10.1248/bpb.b22-00727

2022年

Sugiura, S; Yamahira, S; Tamura, M; Shin, K; Shibuta, M; Satoh, T; Matsuzawa, Y; Fujii, G; Yanagawa, F; Mutoh, M; Yanagisawa, M; Kato, R; Matsui, H.
Automated cell isolation from photodegradable hydrogel based on fluorescence image analysis.
BIOTECHNOL BIOENG. 2023 Mar 15. doi: 10.1002/bit.28375
Murata, Y; Jitsukawa, T; Iida, M; Furuta, T; Haramoto, Y; Shigeri, Y; Fujisaki, S.
Liquid chromatography-mass spectrometry analyses of polyprenyl phosphates in Escherichia coli cells in which genes for isoprenoid synthesis are amplified.
J BIOSCI BIOENG. 2023 Mar 1:S1389-1723(23)00047-6. doi: 10.1016/j.jbiosc.2023.02.003
Shin, WH; Kumazawa, K; Imai, K; Hirokawa, T; Kihara, D.
Quantitative comparison of protein-protein interaction interface using physicochemical feature-based descriptors of surface patches.
FRONT MOL BIOSCI. 2023 Feb 6;10:1110567. doi: 10.3389/fmolb.2023.1110567
Mawaribuchi, S; Ito, M; Ogata, M; Yoshimura, Y; Miura, I.
Parallel Evolution of Sex-Linked Genes across XX/XY and ZZ/ZW Sex Chromosome Systems in the Frog Glandirana rugosa.
GENES (Basel). 2023 Jan 18;14(2):257. doi: 10.3390/genes14020257
Rangasami, VK; Asawa, K; Teramura, Y; Le, Blanc K; Nilsson, B; Hilborn, J; Varghese, OP; Oommen, OP.
Biomimetic polyelectrolyte coating of stem cells suppresses thrombotic activation and enhances its survival and function.
BIOMATER ADV. 2023 Feb 8;147:213331. doi: 10.1016/j.bioadv.2023.213331
Sogo, T; Nakao, S; Tsukamoto, T; Ueyama, T; Harada, Y; Ihara, D; Ishida, T; Nakahara, M; Hasegawa, K; Akagi, Y; Kida, YS; Nakagawa, O; Nagamune, T; Kawahara, M; Kawamura, T.
Canonical Wnt signaling activation by chimeric antigen receptors for efficient cardiac differentiation from mouse embryonic stem cells.
INFLAMM REGEN. 2023 Feb 10;43(1):11. doi: 10.1186/s41232-023-00258-6
Kumar, V; Sari, AN; Meidinna, HN; Kaul, A; Basu, B; Ishida, Y; Terao, K; Kaul, SC; Vrati, S; Sundar, D; Wadhwa, R.
Computational and experimental evidence of the anti-COVID-19 potential of honeybee propolis ingredients, caffeic acid phenethyl ester and artepillin c.
PHYTOTHER RES. 2023 Feb 9. doi: 10.1002/ptr.7717
Sato, Y; Kato, Y; Iizumi, Y; Morimoto, T; Kobashi, K; Sugino, T; Tateno, H; Okazaki, T.
Size distributions of cellulose nanocrystals in dispersions using the centrifugal sedimentation method.
INT J BIOL MACROMOL. 2023 Feb 2:123520. doi: 10.1016/j.ijbiomac.2023.123520
Mawaribuchi, S; Shimomura, O; Oda, T; Hiemori, K; Shimizu, K; Yamase, K; Date, M; Tateno, H.
rBC2LCN-reactive SERPINA3 is a glycobiomarker candidate for pancreatic ductal adenocarcinoma.
GLYCOBIOLOGY. 2023 Feb 2:cwad009. doi: 10.1093/glycob/cwad009
Matsuda, KM; Kotani, H; Yamaguchi, K; Okumura, T; Fukuda, E; Kono, M; Hisamoto, T; Kawanabe, R; Norimatsu, Y; Kuzumi, A; Fukayama, M; Fukasawa, T; Ebata, S; Yoshizaki-Ogawa, A; Okamura, T; Shoda, H; Fujio, K; Goshima, N; Sato, S; Yoshizaki, A.
Significance of anti-transcobalamin receptor antibodies in cutaneous arteritis revealed by proteome-wide autoantibody screening.
J AUTOIMMUN. 2023 Jan 30;135:102995. doi: 10.1016/j.jaut.2023.102995
Itakura, Y; Hasegawa, Y; Kikkawa, Y; Murakami, Y; Sugiura, K; Nagai-Okatani, C; Sasaki, N; Umemura, M; Takahashi, Y; Kimura, T; Kuno, A; Ishiwata, T; Toyoda, M.
Spatiotemporal changes of tissue glycans depending on localization in cardiac aging.
REGEN THER. 2023 Jan 7;22:68-78. doi: 10.1016/j.reth.2022.12.009
Huang, T; Sato, Y; Kuramochi, A; Ohba, Y; Sano, M; Miyagishi, M; Tateno, H; Wadhwa, R; Kawasaki, K; Uchida, T; Ekdahl, KN; Nilsson, B; Chung, UI; Teramura, Y.
Surface modulation of extracellular vesicles with cell-penetrating peptide-conjugated lipids for improvement of intracellular delivery to endothelial cells.
REGEN THER. 2023 Jan 11;22:90-98. doi: 10.1016/j.reth.2022.12.007
Tsuda, M; Nakatani, Y; Baba, S; Tanaka, I; Ichikawa, K; Nonaka, K; Ito, R; Yoko-O, T; Chiba, Y.
Selection of the methylotrophic yeast Ogataea minuta as a high-producing host for heterologous protein expression.
J BIOSCI BIOENG. 2023 Jan 24:S1389-1723(22)00375-9. doi: 10.1016/j.jbiosc.2022.12.006
Yu, Y; Zhang, GX; Li, ZP; Wang, J; Liu, Y; Bhardwaj, R; Wadhwa, R; Nagao, Y; Shichiri, M; Gao, R.
Designed fabrication of active tumor targeting covalent organic framework nanotherapeutics via a simple post-synthetic strategy.
NANO RESEARCH. 03 January 2023. doi: 10.1007/s12274-022-5265-7
Ato, S; Matsunami, H;Ogasawara, R.
Aging is associated with impaired postprandial response of skeletal muscle protein synthesis to high-intensity muscle contraction in mice.
J GERONTOL A BIOL SCI MED SCI. 2023 Jan 12:glad014. doi: 10.1093/gerona/glad014
Mawaribuchi, S; Haramoto, Y; Ikeda, N; Ito, M.
Evolutionary features of ligands and their receptors via protein-protein interactions and essentiality in primates.
GENES CELLS. 2023 Jan 9. doi: 10.1111/gtc.13006
Kudo, F; Kishikawa, K; Tsuboi, K; Kido, T; Usui, T; Hashimoto, J; Shin-Ya, K; Miyanaga, A; Eguchi, T.
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics.
CHEMBIOCHEM. 2023 Jan 5. doi: 10.1002/cbic.202200670
Takeda, H; Busto, JV; Lindau, C; Tsutsumi, A; Tomii, K; Imai, K; Yamamori, Y; Hirokawa, T; Motono, C; Ganesan, I; Wenz, LS; Becker, T; Kikkawa, M; Pfanner, N; Wiedemann, N; Endo, T.
A multipoint guidance mechanism for β-barrel folding on the SAM complex.
NAT STRUCT MOL BIOL. 2023 Jan 5. doi: 10.1038/s41594-022-00897-2
Limjanthong, N; Tohbaru, Y; Okamoto, T; Okajima, R; Kusama, Y; Kojima, H; Fujimura, A; Miyazaki, T; Kanamori, T; Sugiura, S; Ohnuma, K.
Gravity-driven microfluidic device placed on a slow-tilting table enables constant unidirectional perfusion culture of human induced pluripotent stem cells.
J BIOSCI BIOENG. 2022 Dec 29:S1389-1723(22)00346-2. doi: 10.1016/j.jbiosc.2022.11.007
Ishii, N.
C-shaped dipper: A novel useful auxiliary tool for preparation of specimen grids for transmission electron microscopy.
MICROSC RES TECH. 2022 Dec 29. doi: 10.1002/jemt.24283
Hayashida, R; Kikuchi, R; Imai, K; Kojima, W; Yamada, T; Iijima, M; Sesaki, H; Tanaka, K; Matsuda, N; Yamano, K.
Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method.
J BIOL CHEM. 2022 Dec 20:102822. doi: 10.1016/j.jbc.2022.102822
Murotomi, K; Kagiwada, H; Hirano, K; Yamamoto, S; Numata, N; Matsumoto, Y; Kaneko, H; Namihira, M.
Cyclo-glycylproline attenuates hydrogen peroxide-induced cellular damage mediated by the MDM2-p53 pathway in human neural stem cells.
J CELL PHYSIOL. 2022 Dec 31. doi: 10.1002/jcp.30940
Ishimura, R; El-Gowily, AH; Noshiro, D; Komatsu-Hirota, S; Ono, Y; Shindo, M; Hatta, T; Abe, M; Uemura, T; Lee-Okada, HC; TMohamed, TM; Yokomizo, T; Ueno, T; Sakimura, K; Natsume, T; Sorimachi, H; Inada, T; Waguri, S; Noda, NN; Komatsu, M.
The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
NAT COMMUN. 2022 Dec 21;13(1):7857. doi: 10.1038/s41467-022-35501-0
Ando, M; Kawasaki, H; Tamura, S; Haramoto, Y; Shigeri, Y.
Recent Advances in Gas Sensing Technology Using Non-Oxide II-VI Semiconductors CdS, CdSe, and CdTe.
CHEMOSENSORS. 2022 10(11)482. doi: 10.3390/chemosensors10110482
Suzuki, H; Adler, A; Huang, T; Kuramochi, A; Ohba, Y; Sato, Y; Nakamura, N; Manivel, VA; Ekdahl, KN; Nilsson, B; Ishihara, K; Teramura, Y.
Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions.
SCI TECHNOL ADV MATER. 2022 Dec 8;23(1):845-857. doi: 10.1080/14686996.2022.2146466
Zou, X; Lu, J; Deng, Y; Liu, Q; Yan, X; Cui, Y; Xiao, X; Fang, M; Yang, F; Sawaki, H; Sato, T; Tan, B; Lu, X; Feng, B; Kuno, A; Narimatsu, H; Gao, C; Zhang, Y.
ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface.
ONCOGENE. 2022 Dec 17. doi: 10.1038/s41388-022-02571-9
Yoshida, Y; Yajima, Y; Fujikura, Y; Zhuang, H; Higo-Yamamoto, S; Toyoda, A; Oishi, K.
Identification of salivary microRNA profiles in male mouse model of chronic sleep disorder.
Stress. 2022;26(1):21-28. doi: 10.1080/10253890.2022.2156783
Yoshida, Y; Yajima, Y; Kawakami, K; Nakamura, S; Tsukahara, T; Oishi, K; Toyoda, A.
Salivary microRNA and metabolic profiles in a mouse model of subchronic and mild social defeat stress.
Int J Mol Sci. 2022;23:14479. doi: 10.3390/ijms232214479
Horikawa, K; Hashimoto, C; Kikuchi, Y; Makita, M; Oishi, K.
Wheat alkylresorcinol increases fecal lipid excretion and suppresses feed efficiency in mice depending on the time of supplementation.
Nutrition. 2022;103-104:111796. doi: 10.1016/j.nut.2022.111796
Ohkura, N; Taniguchi, M; Oishi, K; Inoue, K; Ohta, M.
Angelica keiskei (Ashitaba) has potential as an antithrombotic health food.
Food Res. 2022;6(2):18-24. doi: 10.26656/fr.2017.6(2).121
Abe, T.
Timing of Medium-Chain Triglyceride Consumption Modulates Effects in Mice with Obesity Induced by a High-Fat High-Sucrose Diet.
NUTRIENTS. 2022 Dec 1;14(23):5096. doi: 10.3390/nu14235096
Nagashima, I; Sugiyama, JI; Shimizu, H.
Study of 400 MHz microwave conduction loss effect for a hydrolysis reaction by thermostable β-Glucosidase HT1.
BIOSCI BIOTECHNOL BIOCHEM. 2022 Dec 6:zbac194. doi: 10.1093/bbb/zbac194
Kuroda, Y; Shimomura, O; Nakahashi, H; Miyazaki, Y; Nakajima, T; Tateno, H; Oda, T.
Lectin-based photoimmunotherapy targeting cell surface glycans for pancreatic cancer.
CANCER RESEARCH 82 (22). 2022 NOV 15. doi: 10.1158/1538-7445.PANCA22-B083
Haji, S; Ito, T; Guenther, C; Nakano, M; Shimizu, T; Mori, D; Chiba, Y; Tanaka, M; Mishra, SK; Willment, JA; Brown, GD; Nagae, M; Yamasaki, S.
Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2.
ELIFE. 2022 Dec 8;11:e83037. doi: 10.7554/eLife.83037
Fukunishi, Y; Higo, J; Kasahara, K.
Computer simulation of molecular recognition in biomolecular system: from in silico screening to generalized ensembles.
BIOPHYS REV. 2022 Nov 28:1-25. doi: 10.1007/s12551-022-01015-8
Kudo, F; Minato, A; Sato, S; Nagano, N; Maruyama, C; Hamano, Y; Hashimoto, J; Kozone, I; Shin-Ya; Eguchi, T.
Mechanism of S-Adenosyl-l-methionine C-Methylation by Cobalamin-dependent Radical S-Adenosyl-l-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis.
ORG LETT. 2022 Dec 2. doi: 10.1021/acs.orglett.2c03555
Kato, K; Okazaki, S; Schmitt-Ulms, C; Jiang, K; Zhou, W; Ishikawa, J; Isayama, Y; Adachi, S; Nishizawa, T; Makarova, KS; Koonin, EV; Abudayyeh, OO; Gootenberg, JS; Nishimasu, H.
RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.
SCIENCE. 2022 Nov 25;378(6622):882-889. doi: 10.1126/science.add7347
Sugio, Y; Yamagami, R; Shigi, N; Hori, H.
A selective and sensitive detection system for 4-thiouridine modification in RNA.
RNA. 2022 Nov 21:rna.079445.122. doi: 10.1261/rna.079445.122
Fujikura, Y; Yamanouchi, K; Sugihara, H; Hatakeyama, M; Abe, T; Ato, S; Oishi, K.
Ketogenic diet containing medium-chain triglyceride ameliorates transcriptome disruption in skeletal muscles of rat models of duchenne muscular dystrophy.
BIOCHEM BIOPHYS REP. 2022 Nov 11;32:101378. doi: 10.1016/j.bbrep.2022.101378
Kuroda, Y; Oda, T; Shimomura, O; Hashimoto, S; Akashi, Y; Miyazaki, Y; Furuya, K; Furuta, T; Nakahashi, H; Louphrasitthiphol, P; Mathis, BJ; Nakajima,T; Tateno, H.
Lectin-based phototherapy targeting cell surface glycans for pancreatic cancer.
INT J CANCER. 2022 Nov 22. doi: 10.1002/ijc.34362
Lintuluoto, M; Abe, M; Horioka, Y; Fukunishi, Y; Tamura, H; M, Lintuluoto J.
Investigation on substrate specificity and catalytic activity of serine protease neuropsin.
BIOPHYS PHYSICOBIOL. 2022 Sep 22;19:e190040. doi: 10.2142/biophysico.bppb-v19.0040
Nohira, N; Shinji, S; Nakamura, S; Nihashi, Y; Shimosato, T; Takaya, T.
Myogenetic Oligodeoxynucleotides as Anti-Nucleolin Aptamers Inhibit the Growth of Embryonal Rhabdomyosarcoma Cells.
BIOMEDICINES. 2022 Oct 25;10(11):2691. doi: 10.3390/biomedicines10112691
Imai, Y;Mori, N; Nihashi, Y; Kumagai, Y; Shibuya, Y; Oshima, J; Sasaki, M; Sasaki, K; Aihara, Y; Sekido, M; Kida, YS.
Therapeutic Potential of Adipose Stem Cell-Derived Conditioned Medium on Scar Contraction Model.
BIOMEDICINES. 2022 Sep 24;10(10):2388. doi: 10.3390/biomedicines10102388
Ekdahl, KN; Fromell, K; Mannes, M; Grinnemo, KH; Huber-Lang, M;Teramura, Y; Nilsson, B.
Therapeutic regulation of complement activation in extracorporeal circuits and intravascular treatments with special reference to the alternative pathway amplification loop.
IMMUNOL REV. 2022 Oct 18. doi: 10.1111/imr.13148
Sano, M; Morishita, K; Onizawa, Y; Takagi, T; Sumaru, K.
Rapid and Highly Sensitive Method for Evaluating Surface Coatings against an Enveloped RNA Virus.
ACS APPL BIO MATER. 2022 Oct 14. doi: 10.1021/acsabm.2c00613
Sugiura, S; Shin, K; Kanamori, T.
Perfusion culture of endothelial cells under shear stress on microporous membrane in a pressure-driven microphysiological system.
J BIOSCI BIOENG. 2022 Oct 14:S1389-1723(22)00258-4. doi: 10.1016/j.jbiosc.2022.09.005
Tirta, YK; Adachi, S; Perez, CAG; Adhitama, N; Nong, QD; Natsume, T; Kato, Y; Watanabe, H.
CELF1 represses Doublesex1 expression via its 5 UTR in the crustacean Daphnia magna.
PLOS ONE. 2022 Oct 14;17(10):e0275526. doi: 10.1371/journal.pone.0275526
Tasaki, M; Tateno, H; Sato, T; Narimatsu, H; Saito, K; Nakagawa, Y; Aoki, T; Kamimura, M; Ushiki, T; Takahashi, K; Tomita, Y.
Hyporesponsiveness against donors ABO antigens of renal grafts after ABO-incompatible kidney transplantation.
CLIN EXP NEPHROL. 2022 Oct 8. doi: 10.1007/s10157-022-02280-3
Hiono, T; Kuno, A.
Glycan Profiling of Viral Glycoproteins with the Lectin Microarray.
METHODS MOL BIOL. 2022;2556:59-68. doi: 10.1007/978-1-0716-2635-1_6
Shefrin, S; Sari, AN; Kumar, V; Zhang, H; Meidinna, HN; Kaul, SC; Wadhwa, R; Sundar, D.
Comparative computational and experimental analyses of some natural small molecules to restore transcriptional activation function of p53 in cancer cells harbouring wild type and p53(Ser46) mutant.
CURR RES STRUCT BIOL. 2022 Sep 13;4:320-331. doi: 10.1016/j.crstbi.2022.09.002
Meidinna, HN; Shefrin, S; Sari, AN; Zhang, H; Dhanjal, JK; Kaul, SC; Sundar, D; Wadhwa, R.
Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1.
FRONT CELL DEV BIOL. 2022 Sep 12;10:918970. doi: 10.3389/fcell.2022.918970
Kosaka, T; Yamaguchi, S; Izuta, S; Yamahira, S; Shibasaki, Y; Tateno, H; Okamoto, A.
Bioorthogonal Photoreactive Surfaces for Single-Cell Analysis of Intercellular Communications.
AM CHEM SOC. 2022 Sep 20. doi: 10.1021/jacs.2c07321
Sato, R; Suzuki, K; Yasuda, Y; Suenaga, A; Fukui, K.
RNAapt3D: RNA aptamer 3D-structural modeling database.
BIOPHYS J. 2022 Sep 22:S0006-3495(22)00773-1. doi: 10.1016/j.bpj.2022.09.023
Kawai, S; Hagihara, R; Shin-Ya, K; Katsuyama, Y; Ohnishi, Y.
Bacterial Avenalumic Acid Biosynthesis Includes Substitution of an Aromatic Amino Group for Hydride by Nitrous Acid Dependent Diazotization.
ANGEW CHEM INT ED ENGL. 2022 Sep 17. doi: 10.1002/anie.202211728
Teranishi, H; Tabata, K; Saeki, M; Umemoto, T; Hatta, T; Otomo, T; Yamamoto, K; Natsume, T; Yoshimori, T; Hamasaki, M.
Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy.
CELL REP. 2022 Sep 13;40(11):111349. doi: 10.1016/j.celrep.2022.111349
Li, S; Ikeuchi, K; Kato, M; Buschauer, R; Sugiyama, T; Adachi, S; Kusano, H; Natsume, T; Berninghausen, O; Matsuo, Y; Becker, T; Beckmann, R; Inada, T.
Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
MOL CELL. 2022 Sep 15;82(18):3424-3437.e8. doi: 10.1016/j.molcel.2022.08.018
Miyazaki, K; Itoh, N; Saiki, P; Kuroki, Y.
Supplementation with Eurycoma longifolia Extract Modulates Diurnal Body Temperature Fluctuation and Sleep Rhythm in Mice.
J NUTR SCI VITAMINOL (Tokyo). 2022;68(4):342-347. doi: 10.3177/jnsv.68.342
Choirunnisa, AR; Arima, K; Abe,Y; Kagaya, K; Kudo, K; Suenaga, H; Hashimoto, J; Fujie, M; Satoh, N; Shin-Ya, K; Matsuda, K; Wakimoto, T.
New azodyrecins identified by a genome mining-directed reactivity-based screening.
BEILSTEIN J ORG CHEM. 2022 Aug 10;18:1017-1025. doi: 10.3762/bjoc.18.102
Yamasaki, K; Adachi, N; Ngwe Tun, MM; Ikeda, A; Moriya, T; Kawasaki, M; Yamasaki, T; Kubota, T; Nagashima, I; Shimizu, H; Tateno, H; Morita, K.
Core fucose-specific Pholiota squarrosa lectin (PhoSL) as a potent broad-spectrum inhibitor of SARS-CoV-2 infection.
FEBS J. 2022 Aug 25. doi: 10.1111/febs.16599
Kagiwada, H; Motono, C; Horimoto, K; Fukui, K.
Phosprof: pathway analysis database of drug response based on phosphorylation activity measurements.
DATABASE (Oxford). 2022 Aug 22;2022:baac072. doi: 10.1093/database/baac072
Higo, J; Kasahara, K; Bekker, GJ; Ma, B; Sakuraba, S; Iida, S; Kamiya, N; Fukuda, I; Kono, H; Fukunishi, Y; Nakamura, H.
Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized flexible molecule.
SCI REP. 2022 Aug 13;12(1):13792. doi: 10.1038/s41598-022-17920-7
Sugiura, S; Satoh, T; Shin, K; Onuki-Nagasaki, R; Kanamori, T.
Perfusion culture of multi-layered HepG2 hepatocellular carcinoma cells in a pressure-driven microphysiological system.
J BIOSCI BIOENG. 2022 Aug 11:S1389-1723(22)00189-X. doi: 10.1016/j.jbiosc.2022.07.001
Tomita, T; Kawano, Y; Kassai, M; Onda, H; Nakajima, Y; Miyazaki, K.
Hydroxy-β-sanshool isolated from Zanthoxylum piperitum (Japanese pepper) shortens the period of the circadian clock.
FOOD FUNCT. 2022 Aug 12. doi: 10.1039/d2fo01036d
Yamagishi, A; Mizusawa, M; Uchida, K; Iijima, M; Kuroda, S; Fukazawa, K; Ishihara, K; Nakamura, C.
Mechanical detection of interactions between proteins related to intermediate filament and transcriptional regulation in living cells.
BIOSENS BIOELECTRON. 2022 Aug 6;216:114603. doi: 10.1016/j.bios.2022.114603
Katsumi, T; Shams, F; Yanagi, H; Ohnishi, T; Toda, M; Lin, SM; Mawaribuchi, S; Shimizu, N; Ezaz, T; Miura, I.
Highly rapid and diverse sex chromosome evolution in the Odorrana frog species complex.
DEV GROWTH DIFFER. 2022 Jul 26. doi: 10.1111/dgd.12800
Numakawa, T; Odaka, H.
The Role of Neurotrophin Signaling in Age-Related Cognitive Decline and Cognitive Diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022 Jul 13;23(14):7726. doi: 10.3390/ijms23147726
Kokubu, R; Ohno, S; Kuratani, H; Takahashi, Y; Manabe, N; Shimizu, H; Chiba, Y; Denda-Nagai, K; Tsuiji, M; Irimura, T; Yamaguchi, Y.
O-Glycan-Dependent Interaction between MUC1 Glycopeptide and MY.1E12 Antibody by NMR, Molecular Dynamics and Docking Simulations.
INT J MOL SCI. 2022 Jul 16;23(14):7855. doi: 10.3390/ijms23147855
Iwamura, C; Hirahara, K; Kiuchi, M; Ikehara, S; Azuma, K; Shimada, T; Kuriyama, S; Ohki, S; Yamamoto, E; Inaba, Y; Shiko, Y; Aoki, A; Kokubo, K; Hirasawa, R; Hishiya, T; Tsuji, K; Nagaoka, T; Ishikawa, S; Kojima, A; Mito, H; Hase, R; Kasahara, Y; Kuriyama, N; Tsukamoto, T; Nakamura, S; Urushibara, T; Kaneda, S; Sakao, S; Tobiume, M; Suzuki, Y; Tsujiwaki, M; Kubo, T; Hasegawa, T; Nakase, H; Nishida, O; Takahashi, K; Baba, K; Iizumi, Y; Okazaki, T; Kimura, MY; Yoshino, I; Igari, H; Nakajima, H; Suzuki, T; Hanaoka, H; Nakada, TA; Ikehara, Y; Yokote, K; Nakayama, T.
Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity.
PROC NATL ACAD SCI USA. 2022 Aug 16;119(33):e2203437119. doi: 10.1073/pnas.2203437119
Yoon, AR; Wadhwa, R; Kaul, SC; Yun, CO.
Why is Mortalin a Potential Therapeutic Target for Cancer.
FRONT CELL DEV BIOL. 2022 Jun 29;10:914540. doi: 10.3389/fcell.2022.914540
Yasuno, R; Mitani, Y; Ohmiya, Y.
Gene Cloning and Functional Analysis of the Luciferase from Luminous Syllids of the Genus Odontosyllis.
METHODS MOL BIOL. 2022;2524:3-15. doi: 10.1007/978-1-0716-2453-1_1
Nagae, M; Hirata, T; Tateno, H; Mishra, SK; Manabe, N; Osada, N; Tokoro, Y; Yamaguchi, Y; Doerksen, RJ; Shimizu, T; Kizuka, Y.
Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A).
COMMUN BIOL. 2022 Jul 19;5(1):695. doi: 10.1038/s42003-022-03661-w
Hirata, Y; Oda, AH; Motono, C; Shiro, M; Ohta, K.
Imputation-free reconstructions of three-dimensional chromosome architectures in human diploid single-cells using allele-specified contacts.
SCI REP. 2022 Jul 11;12(1):11757. doi: 10.1038/s41598-022-15038-4
Fujikura, Y; Kimura, K; Yamanouchi, K; Sugihara, H; Hatakeyama, M; Zhuang, H; Abe, T; Daimon, M; Morita, H; Komuro, I; Oishi, K.
A medium-chain triglyceride containing ketogenic diet exacerbates cardiomyopathy in a CRISPR/Cas9 gene-edited rat model with Duchenne muscular dystrophy.
SCI REP. 2022 Jul 8;12(1):11580. doi: 10.1038/s41598-022-15934-9
Mellul, M; Lahav, S; Imashimizu, M; Tokunaga, Y; Lukatsky, DB; Ram, O.
Repetitive DNA symmetry elements negatively regulate gene expression in embryonic stem cells.
BIOPHYS J. 2022 Jul 8:S0006-3495(22)00557-4. doi: 10.1016/j.bpj.2022.07.011
Viswan, A; Yamagishi, A; Hoshi, M; Furuhata, Y; Kato, Y; Makimoto, N; Takeshita, T; Kobayashi, T; Iwata, F; Kimura, M; Yoshizumi, T; Nakamura, C.
Microneedle Array-Assisted, Direct Delivery of Genome-Editing Proteins Into Plant Tissue.
FRONT PLANT SCI. 2022 Jun 24;13:878059. doi: 10.3389/fpls.2022.878059
Odaka, H.
Genome-wide CRISPR/Cas9 Screening Identifies KDM2B as a Modifier of Heparan Sulfate-Protein Interactions.
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY. 2022 Volume 34 Issue 199 Pages E63. doi: 10.4052/tigg.2203.6E
Omoto, T; Yimiti, D; Sanada, Y; Toriyama, M; Ding, C; Hayashi, Y; Ikuta, Y; Nakasa, T; Ishikawa, M; Sano, M; Lee, M; Akimoto, T; Shukunami, C; Miyaki, S; Adachi, N.
Tendon-Specific Dicer Deficient Mice Exhibit Hypoplastic Tendon Through the Downregulation of Tendon-Related Genes and MicroRNAs.
FRONT CELL DEV BIOL. 2022 Jun 14;10:898428. doi: 10.3389/fcell.2022.898428
Matsuda, K; Arima, K; Akiyama, S; Yamada, Y; Abe, Y; Suenaga, H; Hashimoto, J; Shin-Ya, K; Nishiyama, M; Wakimoto, T.
A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme.
J AM CHEM SOC. 2022 Jun 30. doi: 10.1021/jacs.2c05269
Kanda, GN; Tsuzuki, T; Terada, M; Sakai, N; Motozawa, N; Masuda, T; Nishida, M; Watanabe, CT; Higashi, T; Horiguchi, SA; Taku Kudo, T; Kamei, M; Sunagawa, GA; Matsukuma, K; Sakurada, T; Ozawa, Y; Takahashi, M; Takahashi, K; Natsume, T.
Robotic search for optimal cell culture in regenerative medicine.
ELIFE. 2022 Jun 28;11:e77007. doi: 10.7554/eLife.77007
Yamamoto, K; Takahashi, K; OConnor, SE; Mimura, T.
Imaging MS Analysis in Catharanthus roseus.
METHODS MOL BIOL. 2022;2505:33-43. doi: 10.1007/978-1-0716-2349-7_2
Tsukano, K; Yamamoto, T; Watanabe, T; Michiue, T.
Xenopus Dusp6 modulates FGF signaling to precisely pattern pre-placodal ectoderm.
DEVELOPMENTAL BIOLOGY. 2022 May 16. doi: 10.1016/j.ydbio.2022.05.009
Oinam, L; Tateno, H.
Glycan Profiling by Sequencing to Uncover Multicellular Communication: Launching Glycobiology in Single Cells and Microbiomes.
FRONT CELL DEV BIOL. 2022 May 27;10:919168. doi: 10.3389/fcell.2022.919168
Yang, Y; Akashi, Y; Shimomura, O; Tateno, H; Saito, S; Hiemori, K; Miyazaki, Y; Furuta, T; Kitaguchi, D; Kuroda, Y; Pakavarin, L; Oda, T.
Glycan expression profile of signet ring cell gastric cancer cells and potential applicability of rBC2LCN-targeted lectin drug conjugate therapy.
GASTRIC CANCER. 2022 Jun 17. doi: 10.1007/s10120-022-01312-x
Sasaki, K; Suzuki, M; Sonoda, T; Schneider-Poetsch, T; Ito, A; Takagi, M; Fujishiro, S; Sohtome, Y; Dodo, K; Umehara, T; Aburatani, H; Shin-Ya, K; Nakao, Y; Sodeoka, M; Yoshida, M.
Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells.
CELL CHEM BIOL. 2022 Jun 18:S2451-9456(22)00198-2. doi: 10.1016/j.chembiol.2022.05.006
Miura, I; Shams, F; Jeffries, DL; Katsura, Y; Mawaribuchi, S; Perrin, N; Ito, M; Ogata, M; Ezaz, T.
Identification of ancestral sex chromosomes in the frog Glandirana rugosa bearing XX-XY and ZZ-ZW sex-determining systems.
MOL ECOL. 2022 Jun 12. doi: 10.1111/mec.16551
Wakai, K; Azuma, K; Iwamura, C; Maimaiti, M; Mikami, K; Yoneda, K; Sakamoto, S; Ikehara, S; Yamaguchi, T; Hirahara, K; Ichikawa, T; Nakayama, T; Ikehara, Y.
The new preparation method for paraffin-embedded samples applying scanning electron microscopy revealed characteristic features in asthma-induced mice.
SCI REP. 2022 May 31;12(1):9046. doi: 10.1038/s41598-022-12666-8
Adler, A; Manivel, VA; Fromell, K; Teramura, Y; Ekdahl, KN; Nilsson, B.
A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein.
FRONT IMMUNOL. 2022 May 3;13:891994. doi: 10.3389/fimmu.2022.891994
Matsuda, KM; Yoshizaki, A; Yamaguchi, K; Fukuda, E; Okumura, T; Ogawa, K; Ono, C; Norimatsu, Y; Kotani, H; Hisamoto, T; Kawanabe, R; Kuzumi, A; Fukasawa, T; Ebata, S; Miyagawa, T; Yoshizaki-Ogawa, A; Goshima, N; Sato, S.
Autoantibody Landscape Revealed by Wet Protein Array: Sum of Autoantibody Levels Reflects Disease Status.
FRONT IMMUNOL. 2022 May 4;13:893086. doi: 10.3389/fimmu.2022.893086
Sugisawa, E; Kondo, T; Kumagai, Y; Kato, H; Takayama, Y; Isohashi, K; Shimosegawa, E; Takemura, N; Hayashi, Y; Sasaki, T; Martino, MM; Tominaga, M; Maruyama, K.
Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia.
CELL REP. 2022 Mar 8;38(10):110462. doi: 10.1016/j.celrep.2022.110462
Kuroki, T; Hatta, T; Natsume, T; Sakai, N; Yagi, A; Kato, K; Nagata, K; Kawaguchi, A.
ARHGAP1 Transported with Influenza Viral Genome Ensures Integrity of Viral Particle Surface through Efficient Budozone Formation.
MBIO. 2022 Apr 27:e0072122. doi: 10.1128/mbio.00721-22
Kose, S; Imai, K; Watanabe, A; Nakai, A; Suzuki, Y; Imamoto, N.
Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response.
LIFE SCI ALLIANCE. 2022 May 17;5(9):e202101241. doi: 10.26508/lsa.202101241
Kojima, S; Shiochi, N; Sato, K; Yamaura, M; Ito, T; Yamamura, N; Goto, N; Odamoto, M; Kobayashi, S; Kimura, T; Sekita, Y.
Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.
NUCLEIC ACIDS RESEARCH. 2022 May 11. doi: 10.1093/nar/gkac344
Natsume, T.
Robotic Biology: Robotics and AI Accelerate Life Science.
CANCER SCIENCE. 113; FEB
Kuroda, T; Hattori, Y; Kagami, A; Fukuda, E; Tamura, G.
Genetic modification in the body to make friends with cancer cells?! Dreaming of cancer treatment in 100 years.
CANCER SCIENCE. 113 1517-1517; FEB
Fujimoto, M; Arai, E; Nishiyama, N; Maeshima, A; Fujimoto, H; Kitamura, H; Kuno, A; Yoshida, T; Kanai, Y.
Lectin staining analysis of protein glycosylation in urothelial carcinomas.
CANCER SCIENCE. 113 378-378; FEB
Kitazume, Y; Arai, E; Matsuda, A; Kakuda, S; Ohara, K; Maeshima, A; Kuno, A; Yoshida, T; Kanai, Y.
Alteration of protein glycosylation in renal carcinogenesis.
CANCER SCIENCE. 113 1284-1284; FEB
Demachi, A; Ohte, S; Uchida, R; Shin-Ya, K; Ohshiro, T; Tomoda, H; Ikeda, H.
Discovery of prescopranone, a key intermediate in scopranone biosynthesis.
JOURNAL OF ANTIBIOTICS. 2022 Apr 20. doi: 10.1038/s41429-022-00521-x
Maeda, F; Kato, A; Takeshima, K; Shibazaki, M; Sato, R; Shibata,T; Miyake, K; Kozuka-Hata, H; Oyama, M; Shimizu, E; Imoto, S; Miyano, S; Adachi, S; Natsume, T; Takeuchi, K; Maruzuru, Y; Koyanagi, N; Jun, A; Yasushi, K.
Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1.
J VIROL. 2022 Apr 27:e0030622. doi: 10.1128/jvi.00306-22
Mohamed, HMA; Takahashi, A; Nishijima, S; Adachi, S; Murai, I; Okamura, H; Yamamoto, T.
CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner.
RNA BIOL. 2022;19(1):703-718. doi: 10.1080/15476286.2022.2071026
Rider, SD Jr; Gadgil, RY; Hitch, DC; Damewood, FJ 4th; Zavada, N; Shanahan, M; Alhawach, V; Shrestha, R; Shin-Ya, K; Leffak, M.
Stable G-quadruplex DNA structures promote replication-dependent genome instability.
J BIOL CHEM. 2022 Apr 18:101947. doi: 10.1016/j.jbc.2022.101947
Nagata, Y; Kageyama, S; Ishikawa, T; Kokura, S; Okayama, T; Abe, T; Murakami, M; Otsuka, K; Ariyoshi, T; Kojima, T; Taniguchi, K; Kobayashi, S; Shimada, H; Yajima, S; Suzuki, T; Hirano, S; Tsuchikawa, T; Shichinohe, T; Ueda, S; Kanetaka, K; Yoneda, A; Wada, H; Doki, Y; Yamaue, H; Katsuda, M; Ohi, M; Yasuda, H; Kondo, K; Kataoka, M; Kodera, Y; Koike, M; Shiraishi, T; Miyahara, Y; Goshima,N;Fukuda, E; Yamaguchi, K; Sato, E; Ikeda, H; Yamada, T; Osako, M; Hirai, K; Miyamoto, H; Watanabe, T; Shiku, H.
Prognostic significance of NY-ESO-1 antigen and PIGR expression in esophageal tumors of CHP-NY-ESO-1-vaccinated patients as adjuvant therapy.
CANCER IMMUNOL IMMUNOTHER. 2022 Apr 16. doi: 10.1007/s00262-022-03194-5
Odaka, H; Hiemori, K; Shimoda, A; Akiyoshi, K; Tateno, H.
CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma.
BMC GASTROENTEROLOGY. 2022 Mar 28;22(1):153. doi: 10.1186/s12876-022-02228-7
Hayashi, Y; Yimiti, D; Sanada, Y; Ding, C; Omoto, T; Ogura, T; Nakasa, T; Ishikawa, M; Hiemori, K; Tateno, H; Miyaki, S; Adachi, N.
The therapeutic capacity of bone marrow MSC-derived extracellular vesicles in Achilles tendon healing is passage-dependent and indicated by specific glycans.
FEBS LETTERS. 2022 Apr;596(8):1047-1058. doi: 10.1002/1873-3468.14333
Tasaki, M; Tateno, H; Sato, T; Tomioka, A; Kaji, H; Narimatsu, H; Saito, K; Nakagawa, Y; Aoki, T; Kamimura, M; Ushiki, T; Okada, M; Miwa, Y; Hotta, K; Yoshida, Y; Takahashi, K; Tomita, Y.
A Novel Method of CD31-Combined ABO Carbohydrate Antigen Microarray Predicts Acute Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation.
TRANSPL INT. 2022 Mar 23;35:10248. doi: 10.3389/ti.2022.10248
Oinam, L; Hayashi, R; Hiemori, K; Kiyoi, K; Sage-Ono, K; Miura, K; Ono, M; Tateno, H.
Quantitative evaluation of glycan-binding specificity of recombinant Concanavalin A produced in lettuce (Lactuca sativa).
BIOTECHNOL BIOENG. 2022 Apr 8. doi: 10.1002/bit.28099
Nakagawa, Y; Hishida, T; Hatano, E; Sumaru, K; Morishita, K; Morimoto, M; Yokojima, S; Nakamura, S; Uchida, K.
Photoinduced cytotoxicity of photochromic symmetric diarylethene derivatives: the relation of structure and cytotoxicity.
ORGANIC & BIOMOLECULAR CHEMISTRY. 2022 Apr 13;20(15):3211-3217. doi: 10.1039/d2ob00224h
Miyazaki, Y; Mori, N; Akagi, Y; Oda, T; Kida, YS.
Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts.
CANCERS. 2022 Mar 8;14(6):1375. doi: 10.3390/cancers14061375
Santos, HJ; Hanadate, Y; Imai, K; Watanabe, H; Nozaki, T.
Entamoeba histolytica EHD1 Is Involved in Mitosome-Endosome Contact.
MBIO. 2022 Apr 11:e0384921. doi: 10.1128/mbio.03849-21
Ishii, N.
Systematic Investigation of Lanthanoid Transition Heavy Metal Acetates as Electron Staining Reagents for Protein Molecules in Biological Transmission Electron Microscopy.
MICROSC MICROANAL. 2022 Apr 1:1-10. doi: 10.1017/S1431927622000411
Suenaga, H; Matsuzawa, T; Sahara, T.
Discovery by metagenomics of a functional tandem repeat sequence that controls gene expression in bacteria.
FEMS MICROBIOL ECOL. 2022 Mar 28:fiac037. doi: 10.1093/femsec/fiac037

2021年

Konishi, T; Takahashi, Y; Shiina, Y; Oike, H; Oishi, K.
Time-of-day effects of consumption of fish oil-enriched sausages on serum lipid parameters and fatty acid composition in normolipidemic adults: A randomized, double-blind, placebo-controlled, and parallel-group pilot study.
Nutrition. 2021;90:111247. doi: 10.1016/j.nut.2021.111247
Abdelhady, AM; Hirano, Y; Onizuka, K; Okamura, H; Komatsu, Y; Nagatsugi, F.
Synthesis of Crosslinked 2-OMe RNA Duplexes Using 2-Amino-6-Vinylpurine and Their Application for Effective Inhibition of miRNA Function.
CURR PROTOC. Mar;2(3):e386. doi: 10.1002/cpz1.386
Nagasaki, A; Katoh, K; Hoshi, M; Doi, M; Nakamura, C; Uyeda, TQP.
Characterization of phalloidin-negative nuclear actin filaments in U2OS cells expressing cytoplasmic actin-EGFP.
GENES TO CELLS. 2022 Feb 23. doi: 10.1111/gtc.12930
Seo, N; Nakamura, J; Kaneda, T; Tateno, H; Shimoda, A; Ichiki, T; Furukawa, K; Hirabayashi, J; Akiyoshi, K; Shiku, H.
Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method.
J EXTRACELL VESICLES. 2022 Mar;11(3):e12205. doi: 10.1002/jev2.12205
Araiso, Y; Imai, K; Endo, T.
Role of the TOM Complex in Protein Import into Mitochondria: Structural Views.
ANNU REV BIOCHEM. 2022 Feb 14. doi: 10.1146/annurev-biochem-032620-104527
Tajima, K; Yagi, H; Morisaku, T; Nishi, K; Kushige, H; Kojima, H; Higashi, H; Kuroda, K; Kitago, M; Adachi, S; Natsume, T; Nishimura, K; Oya, M; Kitagawa, Y.
An organ-derived extracellular matrix triggers in situ kidney regeneration in a preclinical model.
NPJ REGEN MED. 2022 Feb 28;7(1):18. doi: 10.1038/s41536-022-00213-y
Ono, J; Koshimizu, U; Fukunishi, Y; Nakai, H.
Multiple protonation states in ligand-free SARS-CoV-2 main protease revealed by large-scale quantum molecular dynamics simulations.
CHEM PHYS LETT. 2022 Feb 22;794:139489. doi: 10.1016/j.cplett.2022.139489
Radhakrishnan, N; Kaul, SC; Wadhwa, R; Sundar, D.
Phosphatidylserine Exposed Lipid Bilayer Models for Understanding Cancer Cell Selectivity of Natural Compounds: A Molecular Dynamics Simulation Study.
MEMBRANES 12 (1);doi: 10.3390/membranes12010064 JAN
Malik, V; Radhakrishnan, N; Kaul, SC; Wadhwa, R; Sundar, D.
Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A and Withanone.
BIOMOLECULES 12 (2);doi: 10.3390/biom12020212 FEB
Nagata, R; Suemune, H; Kobayashi, M; Shinada, T; Shin-Ya, K; Nishiyama, M; Hino, T; Sato, Y; Kuzuyama, T; Nagano, S.
Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-like Enzymes.
ANGEW CHEM INT ED ENGL. 2022 Mar 2. doi: 10.1002/anie.202117430
Mitani, Y; Yasuno, R; Kihira, K; Chung, KM; Mitsuda, N; Kanie, S; Tomioka, A; Kaji, H; Ohmiya, Y.
Host-Dependent Producibility of Recombinant Cypridina noctiluca Luciferase With Glycosylation Defects.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 10;doi: 10.3389/fbioe.2022.774786 FEB 7
Odaka, H; Ozaki, H; Tateno, H.
scGR-seq: Integrated analysis of glycan and RNA in single cells.
STAR PROTOC. 2022 Feb 18;3(1):101179. doi: 10.1016/j.xpro.2022.101179. eCollection
Sari, AN; Dhanjal, JK; Elwakeel, A; Kumar, V; Meidinna, HN; Zhang, H; Ishida, Y; Terao, K; Sundar, D; Kaul, SC; Wadhwa, R.
A Low Dose Combination of Withaferin A and Caffeic Acid Phenethyl Ester Possesses Anti-Metastatic Potential In Vitro: Molecular Targets and Mechanisms.
CANCERS (Basel). 2022 Feb 3;14(3):787. doi: 10.3390/cancers14030787
Irumagawa, S; Hiemori, K; Saito, S; Tateno, H; Arai, R.
Self-Assembling Lectin Nano-Block Oligomers Enhance Binding Avidity to Glycans.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (2);doi: 10.3390/ijms23020676 JAN
Suzuki, R; Nakamura, Y; Koiwai, R; Fuseya, S; Murakami, Y; Hagiwara, K; Sato, T; Takahashi, S; Kudo, T.
Global Loss of Core 1-Derived O-Glycans in Mice Leads to High Mortality Due to Acute Kidney Failure and Gastric Ulcers.
INT J MOL SCI. 2022 Jan 24;23(3):1273. doi: 10.3390/ijms23031273
Saiki, P; Yoshihara, M; Kawano, Y; Miyazaki, H; Miyazaki, K.
Anti-Inflammatory Effects of Heliangin from Jerusalem Artichoke (Helianthus tuberosus) Leaves Might Prevent Atherosclerosis.
BIOMOLECULES 12 (1); doi:10.3390/biom12010091 JAN
Penedo, M; Miyazawa, K; Okano, N; Furusho, H; Ichikawa, T; Alam, MS; Miyata, K; Nakamura, C; Fukuma, T.
Visualizing intracellular nanostructures of living cells by nanoendoscopy-AFM.
SCI ADV. 2021 Dec 24;7(52):eabj4990. doi: 10.1126/sciadv.abj4990. Epub 2021 Dec 22
Sogabe, M; Kojima, S; Kaya, T; Tomioka, A; Kaji, H; Sato, T; Chiba, Y; Shimizu, A; Tanaka, N; Suzuki, N; Hayashi, I; Mikami, M; Togayachi, A; Narimatsu, H.
Sensitive New Assay System for Serum Wisteria floribunda Agglutinin-Reactive Ceruloplasmin That Distinguishes Ovarian Clear Cell Carcinoma from Endometrioma.
ANALYTICAL CHEMISTRY; doi:10.1021/acs.analchem.1c04302
Yamamoto, K; Yoneda, Y; Makino, A; Tanaka, Y; Meng, XY; Hashimoto, J; Shin-Ya, K; Satoh, N; Fujie, M; Toyama, T; Mori, K; Ike, M, Morikawa, M; Kamagata, Y; Tamaki, H.
Draft Genome Sequence of Bryobacteraceae Strain F-183.
MICROBIOL RESOUR ANNOUNC. 2022 Jan 13:e0045321. doi: 10.1128/mra.00453-21
Malik, V; Kumar, V; Kaul, SC; Wadhwa, R; Sundar, D.
Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl ester as ATP-competitive inhibitors of BRAF: A bioinformatics study.
CURR RES STRUCT BIOL. 2021 Nov 18;3:301-311. doi: 10.1016/j.crstbi.2021.11.004
Goel, I; Noiri, M; Yamauchi, Y; Kato, K; Chung, UI; Teramura, Y.
Enhancement of intercellular interaction between iPSC-derived neural progenitor cells and activated endothelial cells using cell surface modification with functional oligopeptides.
BIOMATER SCI. 2022 Jan 11. doi: 10.1039/d1bm01503f
Kaul, A; Kuthethur, R; Ishida, Y; Terao, K; Wadhwa, R; Kaul, SC.
Molecular Insights into the Antistress Potentials of Brazilian Green Propolis Extract and Its Constituent Artepillin C.
MOLECULES. 2021 Dec 23;27(1):80. doi: 10.3390/molecules27010080
Hori, K; Yoshimoto, S; Yoshino, T; Zako, T; Hirao, G; Fujita, S; Nakamura, C; Yamagishi, A; Kamiya, N.
Recent advances in research on biointerfaces: From cell surfaces to artificial interfaces.
J BIOSCI BIOENG. 2022 Jan 5:S1389-1723(21)00331-5. doi: 10.1016/j.jbiosc.2021.12.004
Ogata, H; Akita, S; Ikehara, S; Azuma, K; Yamaguchi, T; Maimaiti, M; Maezawa, Y; Kubota, Y; Yokote, K; Mitsukawa, N; Ikehara, Y.
Calcification in Werner syndrome associated with lymphatic vessels aging.
AGING (Albany NY). 2021 Dec 27;13(undefined). doi: 10.18632/aging.203789
Hirose, J; Watanabe, T; Futagami, T; Fujihara, H; Kimura, N; Suenaga, H; Goto, M; Suyama, A; Furukawa, K.
A New ICEclc Subfamily Integrative and Conjugative Element Responsible for Horizontal Transfer of Biphenyl and Salicylic Acid Catabolic Pathway in the PCB-Degrading Strain Pseudomonas stutzeri KF716.
MICROORGANISMS. 2021 Nov 29;9(12):2462. doi: 10.3390/microorganisms9122462
Matsuzawa, T; Watanabe, M; Nakamichi, Y; Kameyama, A; Kojima, N; Yaoi, K.
Characterization of an extracellular α-xylosidase involved in xyloglucan degradation in Aspergillus oryzae.
APPL MICROBIOL BIOTECHNOL. 2021 Dec 31. doi: 10.1007/s00253-021-11744-7
Nagai-Okatani, C; Zou, X; Matsuda, A; Itakura, Y; Toyoda, M; Zhang, Y; Kuno, A.
Tissue Glycome Mapping: Lectin Microarray-Based Differential Glycomic Analysis of Formalin-Fixed Paraffin-Embedded Tissue Sections.
METHODS MOL BIOL. 2022;2460:161-180. doi: 10.1007/978-1-0716-2148-6_10
Radhakrishnan, N; Dhanjal, JK; Sari, AN; Ishida, Y; Terao, K; Kaul, SC; Sundar, D; Wadhwa, R.
Caffeic acid phenethyl ester (CAPE) confers wild type p53 function in p53(Y220C) mutant: bioinformatics and experimental evidence.
DISCOVER ONCOLOGY 12 (1);doi: 10.1007/s12672-021-00461-2 DEC 20
Oinam, L; Tateno, H.
Evaluation of Glycan-Binding Specificity by Glycoconjugate Microarray with an Evanescent-Field Fluorescence Detection System.
METHODS MOL BIOL. 2022;2460:25-32. doi: 10.1007/978-1-0716-2148-6_2
Higashi, H; Yagi, H; Kuroda, K; Tajima, K; Kojima, H; Nishi, K; Morisaku, T; Hirukawa, K; Fukuda, K; Matsubara, K; Kitago, M; Shinoda, M; Obara, H; Adachi, S; Nishimura, K; Natsume, T; Tomi, M; Soto-Gutierrez, A; Kitagawa, Y.
Transplantation of Bioengineered Liver Capable of Extended Function in a Preclinical Liver Failure Model.
AM J TRANSPLANT. 2021 Dec 21. doi: 10.1111/ajt.16928
Aizawa, S; Nishimura, K; Mondejar, GS; Kumar, A; Bui, PL; Tran, YTH; Kuno, A; Muratani, M; Kobayashi, S; Nabekura, T; Shibuya, A; Sugihara, E; Sato, TA; Fukuda, A; Hayashi, Y; Hisatake, K.
Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming.
STEM CELL REPORTS. 2021 Nov 29:S2213-6711(21)00589-0. doi10.1016/j.stemcr.2021.11.008
Zhang, M; Kiyono, T; Aoki, K; Goshima, N; Kobayashi, S; Hiranuma, K; Shiraishi, K; Saya, H; Nakahara, T.
Development of an in vitro carcinogenesis model of HPV induced cervical adenocarcinoma.
CANCER SCI. 2021 Dec 21. doi: 10.1111/cas.15246
Kaifu, T; Yabe, R; Maruhashi, T; Chung, SH; Tateno, H; Fujikado, N; Hirabayashi, J; Iwakura, Y.
DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis.
J EXP MED. 2021 Dec 6;218(12):e20210435. doi: 10.1084/jem.20210435. Epub 2021 Nov
Shimoda, A; Miura, R; Tateno, H; Seo, N; Shiku, H; Sawada, S; Sasaki, Y; Akiyoshi, K.
Assessment of Surface Glycan Diversity on Extracellular Vesicles by Lectin Microarray and Glycoengineering Strategies for Drug Delivery Applications.
SMALL METHODS; doi: 10.1002/smtd.202100785
Tulin, EKC; Nakazawa, C; Nakamura, T; Saito, S; Ohzono, N; Hiemori, K; Nakakita, SI; Tateno, H; Tonozuka, T; Nishikawa, A.
Glycan detecting tools developed from the Clostridium botulinum whole hemagglutinin complex.
SCI REP. 2021 Nov 9;11(1):21973. doi: 10.1038/s41598-021-01501-1
Kaigawa, H; Tateno, H; Arai, R.
Self-Assembling Functional Complexes of Protein Nanobuilding Blocks with a Trimeric Lectin.
PROTEIN SCIENCE 30 158-159; OCT
Irumagawa, S; Tateno, H; Arai, R.
Self-Assembling Lectin Nano-Building Blocks Enhance Avidity to Glycans through Polyvalent Effect.
PROTEIN SCIENCE 30 173-174; OCT
Takayanagi, S; Watanabe, K; Maruyama, T; Ogawa, M; Morishita, K; Soga, M; Hatta, T; Natsume, T; Hirano, T; Kagechika, H; Hattori, K; Naguro, I; Ichijo, H.
ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes.
SCI REP. 2021 Nov 10;11(1):22009. doi: 10.1038/s41598-021-01123-7
Shigi, N.
Biosynthesis and Degradation of Sulfur Modifications in tRNAs.
INT J MOL SCI. 2021 Nov 3;22(21):11937. doi: 10.3390/ijms222111937
Hurd, MD; Goel, I; Sakai, Y; Teramura, Y.
Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine.
REGENERATIVE THERAPY 18 408-417; doi:10.1016/j.reth.2021.09.009 DEC
Queliconi BB, Kojima W, Kimura M, Imai K, Udagawa C, Motono C, Hirokawa T, Tashiro S, Caaveiro JMM, Tsumoto K, Yamano K, Tanaka K, Matsuda N.
Unfolding is the driving force for mitochondrial import and degradation of Parkinsons disease-related protein DJ-1.
J CELL SCI. 2021 Oct 22:jcs.258653. doi: 10.1242/jcs.258653
Wang, J; Zhang, H; Kaul, A; Li, K; Priyandoko, D; Kaul, SC; Wadhwa, R.
Effect of Ashwagandha Withanolides on Muscle Cell Differentiation.
BIOMOLECULES. 2021 Oct 4;11(10):1454. doi: 10.3390/biom11101454
Kumar, V; Sari, AN; Meidinna, HN; Dhanjal, JK; Subramani, C; Basu, B; Kaul, SC; Vrati, S; Sundar, D; Wadhwa, R.
Computational and in vitro experimental analyses of the anti-COVID-19 potential of Mortaparib and MortaparibPlus.
BIOSCI REP. 2021 Oct 29;41(10):BSR20212156. doi: 10.1042/BSR20212156
Adler, A; Inoue, Y; Ekdahl, KN; Baba, T; Ishihara, K; Nilsson, B; Teramura, Y.
Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins.
J MATER CHEM B. 2021 Oct 7. doi: 10.1039/d1tb01485d
Sano, M; Morishita, K; Oikawa, S; Akimoto, T; Sumaru, K; Kato, Y.
Live-cell imaging of microRNA expression with post-transcriptional feedback control.
MOL THER NUCLEIC ACIDS. 2021 Aug 26;26:547-556. doi: 10.1016/j.omtn.2021.08.018
Tsutsumi, H; Moriwaki, Y; Terada, T; Shimizu, K; Shin-Ya, K; Katsuyama, Y; Ohnishi, Y.
Structural and Molecular Basis of the Catalytic Mechanism of Geranyl Pyrophosphate C-6 Methyltransferase: Creation of an Unprecedented Farnesyl Pyrophosphate C-6 Methyltransferase.
ANGEW CHEM INT ED ENGL. 2021 Oct 9. doi: 10.1002/anie.202111217
Nakatani, E; Yamazaki, W; Sugiura, S; Kanamori, T; Ohnuma, K.
Modeling of differentiation pattern formation in human induced pluripotent stem cells mediated by BMP4 and its inhibitor noggin secreted from cells.
BIOCHEMICAL ENGINEERING JOURNAL 176; doi: 10.1016/j.bej.2021.108159 DEC
Hoshi, K; Ito, H; Abe, E; Fuwa, TJ; Kanno, M; Murakami, Y; Abe, M; Murakami, T, Yoshihara, A, Ugawa, Y, Saito, T, Saido, TC, Matsumoto, K, Yamaguchi, Y, Furukawa, K, Arai, H, Kanai, M, Miyajima, M, Arai, H, Ogawa, N, Akatsu, H, Hashizume, Y, Tateno, H, Honda, T, Hashimoto, Y.
Transferrin Biosynthesized in the Brain Is a Novel Biomarker for Alzheimers Disease.
METABOLITES. 2021 Sep 10;11(9):616. doi: 10.3390/metabo11090616
Angata, K; Wagatsuma, T; Togayachi, A; Sato, T; Sogabe, M; Tajiri, K; Ozawa, T; Nagashima, I; Shimizu, H; Iijima, S; Korenaga, M; Kuno, A; Kaji, H; Mizokami, M; Narimatsu, H.
O-glycosylated HBsAg peptide can induce specific antibody neutralizing HBV infection.
BIOCHIM BIOPHYS ACTA GEN SUBJ. 2021 Sep 25:130020. doi: 10.1016/j.bbagen.2021.130020
Fujikura, Y; Sugihara, H; Hatakeyama, M; Oishi, K; Yamanouchi, K.
Ketogenic diet with medium-chain triglycerides restores skeletal muscle function and pathology in a rat model of Duchenne muscular dystrophy.
FASEB J. 2021 Sep;35(9):e21861. doi: 10.1096/fj.202100629R
Bhargava, P; Mahanta, D; Kaul, A; Ishida, Y; Terao, K; Wadhwa, R; Kaul, SC.
Experimental Evidence for Therapeutic Potentials of Propolis.
NUTRIENTS. 2021 Jul 24;13(8):2528. doi: 10.3390/nu13082528
Kumar, A; Konar, A; Garg, S; Kaul, SC; Wadhwa, R.
Experimental evidence and mechanism of action of some popular neuro-nutraceutical herbs.
NEUROCHEMISTRY INTERNATIONAL 149; doi: 10.1016/j.neuint.2021.105124
Takeuchi, K; Kofuku, Y; Imai, S; Ueda, T; Tokunaga, Y; Toyama, Y; Shiraishi, Y; Shimada, I.
Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR.
MEMBRANES (Basel). 2021 Aug 9;11(8):604. doi: 10.3390/membranes11080604
Yoko-O, T; Komatsuzaki, A; Yoshihara, E; Zhao, S; Umemura, M; Gao, XD; Chiba, Y.
Regulation of alcohol oxidase gene expression in methylotrophic yeast Ogataea minuta.
J BIOSCI BIOENG. 2021 Aug 27:S1389-1723(21)00204-8. doi: 10.1016/j.jbiosc.2021.08.001
Kaul, Z; Cheung, CTY; Bhargava, P; Sari, AN ; Yu, Y; He, HF; Bid, H; Henson, JD; Groden, J; Reddel, RR; Kaul, SC; Wadhwa, R.
Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells.
SCI REP. 2021 Aug 23;11(1):17052. doi: 10.1038/s41598-021-96096-y
Isaka, E; Sugiura, T; Hashimoto, K; Kikuta, K; Anazawa, U; Nomura, T; Kameyama, A.
Characterization of tumor-associated MUC1 and its glycans expressed in mucoepidermoid carcinoma.
ONCOLOGY LETTERS 22 (4);doi: 10.3892/ol.2021.12963 OCT
Minoshima, F; Ozaki, H; Odaka, H; Tateno, H.
Integrated analysis of glycan and RNA in single cells.
ISCIENCE. 2021 Jul 17;24(8):102882. doi: 10.1016/j.isci.2021.102882. eCollection
Funakoshi, Y; Ohji, G; Yakushijin, K; Ebisawa, K; Arakawa, Y; Saegusa, J; Matsumoto, H; Imanishi, T; Fukuda, E; Matsutani, T; Mori, Y; Iwata, K; Minami, H.
Massive surge of mRNA expression of clonal B-cell receptor in patients with COVID-19.
HELIYON. 2021 Aug;7(8):e07748. doi: 10.1016/j.heliyon.2021.e07748. Epub 2021 Aug 10
Watanabe, T; Takeda, K; Hiemori, K; Minamisawa, T; Tateno, H.
A glycosaminoglycan microarray identifies the binding of SARS-CoV-2 spike protein to chondroitin sulfate E.
FEBS LETT. 2021 Aug 10. doi: 10.1002/1873-3468.14173
Perez, CAG; Adachi, S; Nong, QD; Adhitama, N; Matsuura, T; Natsume, T; Wada, T; Kato, Y; Watanabe, H.
Sense-overlapping lncRNA as a decoy of translational repressor protein for dimorphic gene expression.
PLOS GENET. 2021 Jul 28;17(7):e1009683. doi: 10.1371/journal.pgen.1009683
Kimura, M; Imai, K; Morinaka, Y; Hosono-Sakuma, Y; Horton, P; Imamoto, N.
Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding.
SCI REP. 2021 Aug 2;11(1):15649. doi: 10.1038/s41598-021-94948-1
Sato, Y; Asawa, K; Huang, T; Noiri, M; Nakamura, N; Ekdahl, KN; Nilsson, B; Ishihara, K; Teramura, Y.
Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids.
LANGMUIR. 2021 Aug 3. doi: 10.1021/acs.langmuir.1c01072
Suenaga, H; Kagaya, N; Kawada, M; Tatsuda, D; Sato, T; Shin-Ya, K.
Phenotypic screening system using three-dimensional (3D) culture models for natural product screening.
J ANTIBIOT (Tokyo). 2021 Jul 29. doi: 10.1038/s41429-021-00457-8
Konno, S; Kobayashi, K; Senda, M; Funai, Y; Seki, Y; Tamai, I; Schäkel, L; Sakata, K; Pillaiyar, T; Taguchi, A; Taniguchi, A; Gütschow, M; Müller, CE; Takeuchi, K; Hirohama, M; Kawaguch,i A; Kojima, M; Senda, T; Shirasaka, Y; Kamitani, W; Hayashi, Y.
3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.
J MED CHEM. 2021 Jul 27. doi: 10.1021/acs.jmedchem.1c00665
Motono, C; Yanagida, S; Sato, M; Hirokawa, T.
MDContactCom: a tool to identify differences of protein molecular dynamics from two MD simulation trajectories in terms of interresidue contacts.
BIOINFORMATICS. 2021 Jul 21:btab538. doi: 10.1093/bioinformatics/btab538
Adler, A; Inoue, Y; Sato, Y; Ishihara, K; Ekdahl, KN; Nilsson, B; Teramura, Y.
Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions.
BIOMATER SCI. 2021 Jul 20. doi: 10.1039/d1bm00570g
Haramoto, Y.
First person - Yoshikazu Haramoto.
BIOLOGY OPEN 10 (4);doi: 10.1242/bio.058759 APR
Seimiya, H; Nagasawa, K; Shin-Ya, K.
Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics.
J ANTIBIOT (Tokyo). 2021 Jul 20. doi: 10.1038/s41429-021-00454-x
Mostafa, Abdelhady A; Hirano, Y; Onizuka, K; Okamura, H; Komatsu, Y; Nagatsugi, F.
Synthesis of Crosslinked 2-OMe RNA Duplexes and Their Application for Effective Inhibition of miRNA Function.
BIOORG MED CHEM LETT. 2021 Jul 8:128257. doi: 10.1016/j.bmcl.2021.128257
Iida, S; Fukunishi, Y.
Asymmetric dynamics of dimeric SARS-CoV-2 and SARS-CoV main proteases in an apo form: Molecular dynamics study on fluctuations of active site, catalytic dyad, and hydration water.
BBA ADV. 2021;1:100016. doi: 10.1016/j.bbadva.2021.100016. Epub 2021 Jun 20
Ninomiya, K; Iwakiri, J; Aly, MK; Sakaguchi, Y; Adachi, S; Natsume, T; Terai, G; Asai, K; Suzuki, T; Hirose, T.
m(6) A modification of HSATIII lncRNAs regulates temperature-dependent splicing.
EMBO J. 2021 Jun 29:e107976. doi: 10.15252/embj.2021107976
Elwakeel, A; Sari, AN; Dhanjal, JK; Meidinna, HN; Sundar, D; Kaul, SC; Wadhwa, R.
Mutant p53(L194F) Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to Mortaparib(Plus), a Multimodal Small Molecule Inhibitor.
CANCERS (Basel). 2021 Jun 18;13(12):3043. doi: 10.3390/cancers13123043
Noro, E; Matsuda,A; Kyoutou,T; Sato, T; Tomioka,A; Nagai,M; Sogabe,M; Tsuruno,C; Takahama,Y; Kuno, A; Tanaka,Y; Kaji, H; Narimatsu, H.
N-glycan structures of Wisteria floribunda agglutinin-positive Mac2 binding protein in the serum of patients with liver fibrosis.
GLYCOBIOLOGY. 2021 Jun 29:cwab060. doi: 10.1093/glycob/cwab060
Hashimoto, M; Murai, Y; Morita, K; Kikukawa, T; Takagi, T; Takahashi, H; Yokoyama, Y; Amii, H; Sonoyama, M.
Comparison of functionality and structural stability of bacteriorhodopsin reconstituted in partially fluorinated dimyristoylphosphatidylcholine liposomes with different perfluoroalkyl chain lengths.
BIOCHIM BIOPHYS ACTA BIOMEMBR. 2021 Jun 25;1863(10):183686. doi: 10.1016/j.bbamem.2021.183686
Ogita, Y; Tamura, K; Mawaribuchi, S; Takamatsu, N; Ito, M.
Independent pseudogenizations and losses of sox15 during amniote diversification following asymmetric ohnolog evolution.
BMC ECOL EVOL. 2021 Jun 30;21(1):134. doi: 10.1186/s12862-021-01864-z
Yamagishi, A; Ito, F; Nakamura, C.
Study on Cancer Cell Invasiveness via Application of Mechanical Force to Induce Chloride Ion Efflux.
ANAL CHEM. 2021 Jun 21. doi: 10.1021/acs.analchem.1c01589
Tomita, T; Wadhwa, R; Kaul, SC; Kurita, R; Kojima, N; Onishi, Y.
Withanolide Derivative 2,3-Dihydro-3β-methoxy Withaferin-A Modulates the Circadian Clock via Interaction with RAR-Related Orphan Receptor α (RORa.
J NAT PROD. 2021 Jun 21. doi: 10.1021/acs.jnatprod.0c01276
Kagiwada, H; Kiboku, T; Matsuo, H; Kitazawa, M; Fukui, K; Horimoto, K.
Assessing the activation/inhibition of tyrosine kinase-related pathways with a newly developed platform.
PROTEOMICS. 2021 Jun 21:e2000251. doi: 10.1002/pmic.202000251
Dhanjal, JK; Kumar, V; Garg, S; Subramani, C; Agarwal, S; Wang, J; Zhang, H; Kaul, A; Kalra, RS; Kaul, SC; Vrati, S; Sundar, D; Wadhwa, R
Molecular mechanism of anti-SARS-CoV2 activity of Ashwagandha-derived withanolides
Int J Biol Macromol. 2021 Jun 9:S0141-8130(21)01215-0. doi: 10.1016/j.ijbiomac.2021.06.015
Furuta, T; Oda, T; Kiyoi, K; Ozawa, Y; Kimura, S; Kurimori, K; Miyazaki, Y; Yu, Y; Furuya, K; Akashi, Y; Shimomura, O; Tateno, H
Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells
Cancer Sci. 2021 Jun 11. doi: 10.1111/cas.15023
Okumura, S; Hirano, Y; Komatsu, Y.
Stable duplex-linked antisense targeting miR-148a inhibits breast cancer cell proliferation.
SCI REP. 2021 Jun 1;11(1):11467. doi: 10.1038/s41598-021-90972-3
Suzuki, T; Katayama, Y; Komatsu, Y; Kamiya, H.
Similar frequency and signature of untargeted substitutions induced by abasic site analog under reduced human APE1 conditions.
J TOXICOL SCI. 2021;46(6):283-288. doi: 10.2131/jts.46.283
Numakawa, T; Odaka, H.
Brain-Derived Neurotrophic Factor Signaling in the Pathophysiology of Alzheimers Disease: Beneficial Effects of Flavonoids for Neuroprotection.
INT J MOL SCI. 2021 May 27;22(11):5719. doi: 10.3390/ijms22115719
Yoneda, Y; Yamamoto, K; Makino, A; Tanaka, Y; Meng, XY; Hashimoto, J; Shin-Ya, K; Satoh, N; Fujie, M; Toyama, T; Mori, K; Ike, M; Morikawa, M; Kamagata, Y; Tamaki, H
Novel Plant-Associated Acidobacteria Promotes Growth of Common Floating Aquatic Plants, Duckweeds
Microorganisms. 2021 May 24;9(6):1133. doi: 10.3390/microorganisms9061133
Mogi, K; Kimura, H; Kondo, Y; Inoue, T; Adachi, S; Natsume, T.
Automatic radioisotope manipulation for small amount of nuclear medicine using an EWOD device with a dimple structure.
R SOC OPEN SCI. 2021 May 26;8(5):201809. doi: 10.1098/rsos.201809
Nishimura, T; Kawahara, T; Kagaya, N; Ogura, Y; Takikawa, H; Suenaga, H; Adachi, M; Hirokawa, T; Doi, T; Shin-Ya, K.
JBIR-155, a Specific Class D β-Lactamase Inhibitor of Microbial Origin.
ORG LETT. 2021 May 24. doi: 10.1021/acs.orglett.1c01352
Kudo, K; Nishimura, T; Kozone, I; Hashimoto, J; Kagaya, N; Suenaga, H; Ikeda, H; Shin-Ya, K.
Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase.
SCI REP. 2021 May 11;11(1):9944. doi: 10.1038/s41598-021-88583-z
Amemiya, T; Horimoto, K; Fukui, K.
Application of multiple omics and network projection analyses to drug repositioning for pathogenic mosquito-borne viruses.
SCI REP. 2021 May 12;11(1):10136. doi: 10.1038/s41598-021-89171-x
Sakata-Matsuzawa, M; Denda-Nagai, K; Fujihira, H; Noji, M; Ishii-Schrade, KB; Matsuda, A; Kuno, A; Okazaki, M; Nakai, K; Horimoto, Y; Saito, M; Irimura, T
Glycans unique to the relapse-prone subset within triple-negative breast cancer as revealed by lectin array-based analysis of surgical specimens
PLoS One. 2021 May 11;16(5):e0250747. doi: 10.1371/journal.pone.0250747. eCollection
Baba, T; Tanimura, S; Yamaguchi, A; Horikawa, K; Yokozeki, M; Hachiya, S; Iemura, SI; Natsume, T; Matsuda, N; Takeda, K.
Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteinsduring mitophagy.
BIOCHIM BIOPHYS ACTA MOL CELL RES. 2021 Apr 16:119045. doi: 10.1016/j.bbamcr.2021.119045
Tokunaga, Y; Tanaka, M; Iida, H; Kinoshita, M; Tojima, Y; Takeuchi, K; Imashimizu, M.
Nonthermal excitation effects mediated by subterahertz radiation on hydrogen exchange in ubiquitin
BIOPHYS J. 2021 Apr 21:S0006-3495(21)00329-5. doi: 10.1016/j.bpj.2021.04.013
Akagi, Y; Mori, N; Kawamura, T; Takayama, Y; Kida, YS.
Non-invasive cell classification using the Paint Raman Express Spectroscopy System (PRESS)
SCI REP. 2021 Apr 23;11(1):8818. doi: 10.1038/s41598-021-88056-3
Liu, C; Hashimoto, J; Kudo, K; Shin-Ya, K; Kakeya, H.
An Atypical Arginine Dihydrolase Involved in the Biosynthesis of Cyclic Hexapeptide Longicatenamides.
CHEM ASIAN J. 2021 Apr 22. doi: 10.1002/asia.202100181
Kaneko, S; Mitsuyama, T; Shiraishi, K; Ikawa, N; Shozu, K; Dozen, A; Machino, H; Asada, K; Komatsu, M; Kukita, A; Sone, K; Yoshida, H; Motoi, N; Hayami, S; Yoneoka, Y; Kato, T; Kohno, T; Natsume, T; Keudell, GV; Saloura, V; Yamaue, H; Hamamoto, R
Genome-Wide Chromatin Analysis of FFPE Tissues Using a Dual-Arm Robot with Clinical Potential
Cancers (Basel). 2021 Apr 28;13(9):2126. doi: 10.3390/cancers13092126
Li, X; Wang, J; Zhang, H; Xiao, L; Lei, Z; Kaul, SC; Wadhwa, R; Zhang, Z.
Low Dose of Fluoride in the Culture Medium of Cordyceps militaris Promotes Its Growth and Enhances Bioactives with Antioxidant and Anticancer Properties.
J FUNGI (Basel). 2021 Apr 28;7(5):342. doi: 10.3390/jof7050342
Kohrogi, K; Hino, S; Sakamoto, A; Anan, K; Takase, R; Araki, H; Hino, Y; Araki, K; Sato, T; Nakamura, K; Nakao, M
LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBP
Blood Adv. 2021 May 11;5(9):2305-2318. doi: 10.1182/bloodadvances.2020003521
Okubo, S; Ena, E; Okuda, A; Kozone, I; Hashimoto, J; Nishitsuji, Y; Fujie, M; Satoh, N; Ikeda, H; Shin-Ya, K.
Identification of functional cytochrome P450 and ferredoxin from Streptomyces sp. EAS-AB2608 by transcriptional analysis and their heterologous expression.
APPL MICROBIOL BIOTECHNOL. 2021 May 4. doi: 10.1007/s00253-021-11304-z
Haramoto, Y; Sakata, M; Kobayashi, S.
Visualization of X chromosome reactivation in mouse primordial germ cells in vivo.
BIOL OPEN. 2021 Apr 15;10(4):bio058602. doi: 10.1242/bio.058602. Epub 2021 Apr 29
Mori, N; Kida, YS.
Applicability of Artificial Vascularized Liver Tissue to Proteomic Analysis.
MICROMACHINES (Basel). 2021 Apr 11;12(4):418. doi: 10.3390/mi12040418
Moritsugu, K; Takeuchi, K; Kamiya, N; Higo, J; Yasumatsu, I; Fukunishi, Y; Fukuda, I.
Flexibility and Cell Permeability of Cyclic Ras-Inhibitor Peptides Revealed by the Coupled Nosé-Hoover Equation.
J CHEM INF MODEL. 2021 Apr 9. doi: 10.1021/acs.jcim.0c01427
Penedo, M; Shirokawa, T; Alam, MS; Miyazawa, K; Ichikawa, T; Okano, N; Furusho, H; Nakamura, C; Fukuma, T.
Cell penetration efficiency analysis of different atomic force microscopy nanoneedles into living cells.
SCI REP. 2021 Apr 8;11(1):7756. doi: 10.1038/s41598-021-87319-3
Ohashi, H; Watashi, K; Saso, W; Shionoya, K; Iwanami, S; Hirokawa, T; Shirai, T; Kanaya, S; Ito, Y; Kim, KS; Nomura, T; Suzuki, T; Nishioka, K; Ando, S; Ejima, K; Koizumi, Y; Tanaka, T; Aoki, S; Kuramochi, K; Suzuki, T; Hashiguchi, T; Maenaka, K; Matano, T; Muramatsu, M; Saijo, M; Aihara, K; Iwami, S; Takeda, M; McKeating, JA; Wakita, T
Potential anti-COVID-19 agents, Cepharanthine and Nelfinavir, and their usage for combination treatment.
ISCIENCE. 2021 Mar 26:102367. doi: 10.1016/j.isci.2021.102367
Hirama, H; Otahara, R; Mogi, K; Hayase, M; Torii, T; Mekaru, H.
Rapid Prototyping of a Nanoparticle Concentrator Using a Hydrogel Molding Method.
POLYMERS (Basel). 2021 Mar 29;13(7):1069. doi: 10.3390/polym13071069
Lintuluoto, M; Horioka, Y; Hongo, S; Lintuluoto, JM; Fukunishi, Y.
Molecular Dynamics Simulation Study on Allosteric Regulation of CD44-Hyaluronan Binding as a Force Sensing Mechanism.
ACS OMEGA. 2021 Mar 16;6(12):8045-8055. doi: 10.1021/acsomega.0c05502. eCollection
Kalra, RS; Kumar, V; Dhanjal, JK; Garg, S; Li, X; Kaul, SC; Sundar, D; Wadhwa, R.
COVID19-inhibitory activity of withanolides involves targeting of the host cell surface receptor ACE2: insights from computational and biochemical assays.
J BIOMOL STRUCT DYN. 2021 Apr 2:1-14. doi: 10.1080/07391102.2021.1902858
Katsuyama, Y; Sone, K; Harada, A; Kawai, S; Urano, N; Adachi, N; Moriya, T; Kawasaki, M; Shin-Ya, K; Senda, T; Ohnishi, Y
Structural and functional analyses of the tridomain-nonribosomal peptide synthetase FmoA3 for 4-methyloxazoline ring formation
Angew Chem Int Ed Engl. 2021 Mar 29. doi: 10.1002/anie.202102760
Nakamura, A; Wang, D; Komatsu, Y.
Analysis of GTP addition in the reverse (3-5) direction by human tRNA(His) guanylyltransferase.
RNA. 2021 Mar 23:rna.078287.120. doi: 10.1261/rna.078287.120
Watanabe, T; Tateno, H.
Elimination of cells deviated from human induced pluripotent stem cells with a photoactivatable IR700-labelled antibody.
BIOCHEM BIOPHYS RES COMMUN. 2021 Mar 25;554:13-18. doi: 10.1016/j.bbrc.2021.03.078

2020年

Koiwai K, Morohashi K, Inaba K, Ebihara K, Kojima H, Okabe T, Yoshino R, Hirokawa T, Nampo T, Fujikawa Y, Inoue H, Yumoto F, Senda T, Niwa R
Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo
J Pestic Sci. 2021 Feb 20;46(1):75-87. doi: 10.1584/jpestics.D20-072
Higo J, Takashima H, Fukunishi Y, Yoshimori A
Generalized-ensemble method study: A helix-mimetic compound inhibits protein-protein interaction by long-range and short-range intermolecular interactions.
J COMPUT CHEM. 2021 Mar 23. doi: 10.1002/jcc.26516
Hayami T, Kamiya N, Kasahara K, Kawabata T, Kurita JI, Fukunishi Y, Nishimura Y, Nakamura H, Higo J
Difference of binding modes among three ligands to a receptor mSin3B corresponding to their inhibitory activities.
SCI REP. 2021 Mar 17;11(1):6178. doi: 10.1038/s41598-021-85612-9
Yamamoto K, Honda T, Yokoyama S, Ma L, Kato A, Ito T, Ishizu Y, Kuzuya T, Nakamura M, Kawashima H, Ishigami M, Tsuji NM, Fujishiro M
Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine
Dig Liver Dis. 2021 Mar 13:S1590-8658(21)00081-5. doi: 10.1016/j.dld.2021.02.013
Miyazaki Y, Oda T, Inagaki Y, Kushige H, Saito Y, Mori N, Takayama Y, Kumagai Y, Mitsuyama T, Kida YS
Adipose-derived mesenchymal stem cells differentiate into heterogeneous cancer-associated fibroblasts in a stroma-rich xenograft model.
SCI REP. 2021 Feb 25;11(1):4690. doi: 10.1038/s41598-021-84058-3
Kumagai Y, Hirasawa T, Wachi M
Requirement of the LtsA Protein for Formation of the Mycolic Acid-Containing Layer on the Cell Surface of Corynebacterium glutamicum.
MICROORGANISMS. 2021 Feb 16;9(2):409. doi: 10.3390/microorganisms9020409
Shinohara M, Arakawa H, Oda Y, Shiraki N, Sugiura S, Nishiuchi T, Satoh T, Iino K, Leo S, Kato Y, Araya K, Kawanishi T, Nakatsuji T, Mitsuta M, Inamura K, Goto T, Shinha K, Nihei W, Komori K, Nishikawa M, Kume S, Kato Y, Kanamori T, Sakai Y, Kimura H
Coculture with hiPS-derived intestinal cells enhanced human hepatocyte functions in a pneumatic-pressure-driven two-organ microphysiological system
Sci Rep. 2021 Mar 8;11(1):5437. doi: 10.1038/s41598-021-84861-y
Nagai-Okatani C, Zou X, Fujita N, Sogabe I, Arakawa K, Nagai M, Angata K, Zhang Y, Aoki-Kinoshita KF, Kuno A
LM-GlycomeAtlas Ver. 2.0: An Integrated Visualization for Lectin Microarray-based Mouse Tissue Glycome Mapping Data with Lectin Histochemistry.
J PROTEOME RES. 2021 Mar 4. doi: 10.1021/acs.jproteome.0c00907
Fujimoto M, Arai E, Matsuda A, Maeshima A, Fujimoto H, Kuno A, Yoshida T, Kanai Y
Alterations of protein glycosylation and DNA methylation in urothelial carcinoma.
CANCER SCIENCE 112 670-670; FEB
Sari AN, Elwakeel A, Dhanjal JK,Kumar V, Sundar D, Kaul SC, Wadhwa R
Identification and Characterization of Mortaparib(Plus)-A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms.
CANCERS (Basel). 2021 Feb 17;13(4):835. doi: 10.3390/cancers13040835
Bekker GJ, Fukuda I, Higo J, Fukunishi Y, Kamiya N
Cryptic-site binding mechanism of medium-sized Bcl-xL inhibiting compounds elucidated by McMD-based dynamic docking simulations.
SCI REP. 2021 Mar 3;11(1):5046. doi: 10.1038/s41598-021-84488-z
Furuta T, Tateno H, Kiyoi K, Miyazaki Y, Kimura S, Kurimori K, Shimomura O, Oda T
Glycans on CEA as a targeting ligand of pancreatic ductal adenocarcinoma in novel lectin-drug conjugated therapy.
CANCER SCIENCE 112 718-718; FEB
Okabe S, Shin-ya K, Dan S, Nagasawa K, Seimiya H
Establishment of G-quadruplex ligand-resistant cancer cells and elucidation of the resistance mechanism.
CANCER SCIENCE 112 558-558; FEB
Miyazaki K, Suenaga H, Oshiki M, Kawano S, Fukushima T
Complete Genome Sequence of Thiohalobacter sp. Strain COW1, Isolated from Activated Sludge Treating Coke Oven Wastewater.
MICROBIOL RESOUR ANNOUNC. 2021 Feb 18;10(7):e00013-21. doi: 10.1128/MRA.00013-21
Ueoka R, Hashimoto J, Kozone I, Hashimoto T, Kudo K, Kagaya N, Suenaga H, Ikeda H, Shin-Ya K
A novel methymycin analog, 12-ketomethymycin N-oxide, produced by the heterologous expression of the large pikromycin/methymycin biosynthetic gene cluster of Streptomyces sp. AM4900.
BIOSCI BIOTECHNOL BIOCHEM. 2020 Dec 22:zbaa111. doi: 10.1093/bbb/zbaa111
Higo J, Kusaka A, Kasahara K, Kamiya N, Hayato I, Qilin X, Takahashi T, Fukuda I, Mori K, Hata Y, Fukunishi Y
GA-guided mD-VcMD: A genetic-algorithm-guided method for multi-dimensional virtual-system coupled molecular dynamics
Biophys Physicobiol. 2020 Dec 26;17:161-176. doi: 10.2142/biophysico.BSJ-2020008
Malik V, Kumar V, Kaul SC, Wadhwa R, Sundar D
Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers.
BIOMOLECULES. 2021 Jan 26;11(2):160. doi: 10.3390/biom11020160
Maejima A, Ishibashi K, Kim H, Kumagai I, Asano R
Evaluation of intercellular cross-linking abilities correlated with cytotoxicities of bispecific antibodies with domain rearrangements using AFM force-sensing.
BIOSENS BIOELECTRON. 2021 Jan 27;178:113037. doi: 10.1016/j.bios.2021.113037
Wadhwa R, Yadav NS, Katiyar SP, Yaguchi T, Lee C, Ahn H, Yun CO, Kaul SC, Sundar D
Molecular dynamics simulations and experimental studies reveal differential permeability of withaferin-A and withanone across the model cell membrane.
SCI REP. 2021 Jan 27;11(1):2352. doi: 10.1038/s41598-021-81729-z
Kojima W, Yamano K, Kosako H, Imai K, Kikuchi R, Tanaka K, Matsuda N
Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy.
AUTOPHAGY. 2021 Jan 26:1-26. doi: 10.1080/15548627.2021.1874133
Odaka H, Numakawa T, Soga M, Kido J, Matsumoto S, Kajihara R, Okumiya T, Tani N, Tanoue Y, Fukuda T, Furuya H, Inoue T, Era T
An iPSC-based neural model of sialidosis uncovers glycolytic impairment-causing presynaptic dysfunction and deregulation of Ca(2+) dynamics
Neurobiol Dis. 2021 Jan 28:105279. doi: 10.1016/j.nbd.2021.105279
Kimura S, Oda T, Shimomura O, Enomoto T, Hashimoto S, Kuroda Y, Yu Y, Kurimori K, Furuta T, Miyazaki Y, Tateno H
Novel Pancreatic Cancer Therapy Targeting Cell Surface Glycans by Liposomes Modified with rBC2LCN Lectin
Eur Surg Res. 2021 Jan 27:1-10. doi: 10.1159/000513430
Fukuda E, Tanaka H, Yamaguchi K, Takasaka M, Kawamura Y, Okuda H, Isotani A, Ikawa M, Shapiro VS, Tsuchida J, Okada Y, Tsujimura A, Miyagawa Y, Fukuhara S, Kawakami Y, Wada M, Nishimune Y, Goshima N
Identification and characterization of the antigen recognized by the germ cell mAb TRA98 using a human comprehensive wet protein array
Genes Cells. 2021 Feb 1. doi: 10.1111/gtc.12832
Tsuchida N, Takagi T, Takahashi H, Yoshihara T, Tobita S, Sonoyama M
Membrane properties of amacrocyclic tetraether bisphosphatidylcholine lipid: Effect of a single membrane-spanning polymethylene cross-linkage between two head groups of ditetradecylphosphatidylcholine membrane.
BIOCHIM BIOPHYS ACTA BIOMEMBR. 2021 Feb 4:183569. doi: 10.1016/j.bbamem.2021.183569
Hashimoto T, Hashimoto J, Kagaya N, Nishimura T, Suenaga H, Nishiyama M, Kuzuyama T, Shin-Ya K
A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster.
J ANTIBIOT (Tokyo). 2021 Feb 8. doi: 10.1038/s41429-021-00410-9
Kameyama A, Nishijima R, Yamakoshi K
Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice.
PLOS ONE. 2021 Jan 19;16(1):e0245607. doi: 10.1371/journal.pone.0245607. eCollection
Inagaki H, Haramoto Y, Kubota HY, Shigeri Y
Complete mitochondrial genome sequence of Japanese forest green tree frog (Rhacophorus arboreus.
Mitochondrial DNA B Resour 2020 Sep 16;5(3):3347-3348. doi: 10.1080/23802359.2020.1820396
Takeda H, Tsutsumi A, Nishizawa T, Lindau C, Busto JV, Wenz LS, Ellenrieder L, Imai K, Straub SP, Mossmann W, Qiu J, Yamamori Y, Tomii K, Suzuki J, Murata T, Ogasawara S, Nureki O, Becker T, Pfanner N, Wiedemann N, Kikkawa M, Endo T
Mitochondrial sorting and assembly machinery operates by β-barrel switching.
NATURE. 2021 Jan 6. doi: 10.1038/s41586-020-03113-7
Sasaki S, Ma Y, Ishizuka T, Bao HL, Hirokawa T, Xu Y, Tera M, Nagasawa K
Linear consecutive hexaoxazoles as G4 ligands inducing chair-type anti-parallel topology of a telomeric G-quadruplex.
RSC ADVANCES 10 (71) 43319-43323; doi: 10.1039/d0ra09413g DEC 7
Takeuchi K, Misaki I, Tokunaga Y, Fujisaki M, Kamoshida H, Takizawa T, Hanzawa H, Shimada I
Conformational plasticity of cyclic Ras-inhibitor peptides defines cell permeabilization activity.
ANGEW CHEM INT ED ENGL. 2021 Jan 11. doi: 10.1002/anie.202016647
Udagawa T, Seki M, Okuyama T, Adachi S, Natsume T, Noguchi T, Matsuzawa A, Inada T
Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival.
CELL REP. 2021 Jan 5;34(1):108599. doi: 10.1016/j.celrep.2020.108599
Liu D, Liu G, Li Y, Wang Y, Zheng Y, Sha S, Li W, Kameyama A, Dong W
Rapid glycosylation analysis of mouse serum glycoproteins separated by supported molecular matrix electrophoresis.
J PROTEOMICS. 2021 Jan 6:104098. doi: 10.1016/j.jprot.2020.104098
Imai K, Nakai K
Tools for the Recognition of Sorting Signals and the Prediction of Subcellular Localization of Proteins From Their Amino Acid Sequences.
FRONT GENET 2020 Nov 25;11:607812. doi: 10.3389/fgene.2020.607812. eCollection
Odaka H, Hiemori K, Shimoda A, Akiyoshi K, Tateno H
Platelet-derived extracellular vesicles are increased in sera of Alzheimers disease patients, as revealed by Tim4-based assays.
FEBS OPEN BIO 2020 Dec 20. doi: 10.1002/2211-5463.13068
Higo J, Kawabata T, Kusaka A, Kasahara K, Kamiya N, Fukuda I, Mori K, Hata Y, Fukunishi Y, Nakamura H
Molecular Interaction Mechanism of a 14-3-3 Protein with a Phosphorylated Peptide Elucidated by Enhanced Conformational Sampling.
J. Chem. Inf. Model 60 (10) 4867-4880; (2020) doi: 10.1021/acs.jcim.0c00551 OCT 26
Tokunaga Y, Takeuchi K
Role of NMR in High Ordered Structure Characterization of Monoclonal Antibodies.
Int. J. Mol. Sci. 2021, 22(1), 46; doi: 10.3390/ijms22010046
Shimamoto N, Imashimizu M
RNA Polymerase and Transcription Mechanisms: The Forefront of Physicochemical Studies of Chemical Reactions.
BIOMOLECULES. 2020 Dec 29;11(1):E32. doi: 10.3390/biom11010032
Khaledian B, Taguchi A, Shin-Ya K, Kondo-Ida L, Kagaya N, Suzuki M, Kajino T, Yamaguchi T, Shimada Y, Takahashi T
Inhibition of HSP90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
CANCER SCI. 2020 Dec 28. doi: 10.1111/cas.14786
Toyosaki M, Homma K, Suzuki S, Muraoka N, Hashimoto H, Goshima N, Ieda M, Sasaki J
Dermal fibroblast-like cells reprogrammed directly from adipocytes in mouse.
SCI REP.10(1):21467 (2020) doi: 10.1038/s41598-020-78523-8
Suzuki T, Adachi S, Kikuguchi C, Shibata S, Nishijima S, Kawamoto Y, Iizuka Y, Koseki H, Okano H, Natsume T, Yamamoto T
Regulation of Fetal Genes by Transitions among RNA-Binding Proteins during Liver Development
Int J Mol Sci.;21(23):9319 (2020) doi: 10.3390/ijms21239319
Sakamoto K, Masutani T, Hirokawa T
Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo.
SCI REP. 10(1):21671 (2020) doi: 10.1038/s41598-020-78712-5
Araiso Y, Imai K, Endo T
Structural snapshot of the mitochondrial protein import gate
FEBS J. 2020 Dec 10. doi: 10.1111/febs.15661
Landeira JM, Liu BB, Omura T, Akiba T, Tanaka Y
Salinity effects on the first larval stage of the invasive crab Hemigrapsus takanoi: Survival and swimming patterns
ESTUARINE COASTAL AND SHELF SCIENCE 245; (2020) doi: 10.1016/j.ecss.2020.106976
Hasehira K, Furuta T, Shimomura O, Asada M, Oda T, Tateno H
Quantitative structural analysis of glycans expressed within tumors derived from pancreatic cancer patient-derived xenograft mouse models
Biochem Biophys Res Commun. 2020 Dec 4:S0006-291X(20)32131-8. doi: 10.1016/j.bbrc.2020.11.087
Ochiai K, Motozawa N, Terada M, Horinouchi T, Masuda T, Kudo T, Kamei M, Tsujikawa A, Matsukuma K, Natsume T, Kanda GN, Takahashi M, Takahashi K
A Variable Scheduling Maintenance Culture Platform for Mammalian Cells
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Konar A, Kalra RS, Chaudhary A, Nayak A, Guruprasa KP, Satyamoorthy K, Ishida Y, Terao K, Kaul SC, Wadhwa R
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E190V substitution of H6 hemagglutinin is one of key factors for binding to sulfated sialylated glycan receptor and infection to chickens
Microbiol. Immunol. 73: 171-174 (2020) doi:10.1111/1348-0421.12773
Otani K, Tokudome T, Kamiya CA, Mao Y, Nishimura H, Hasegawa T, Arai Y, Kaneko M, Shioi G, Ishida J, Fukamizu A, Osaki T, Nagai-Okatani C, Minamino N, Ensho T, Hino J, Murata S, Takegami M, Nishimura K, Kishimoto I, Miyazato M, Harada-Shiba M, Yoshimatsu J, Nakao K, Ikeda T, Kangawa K.
Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart
Circulation. 141: 571-588 (2020). doi:10.1161/CIRCULATIONAHA.119.039761
Shimazaki H, Ono A, Tsuruga M, Ueki A, Koseki-Kuno S, Toyoda T, Saito K, Sawakami K, Kariya M, Segawa O, Nakamura K, Koizuka M, Kuno A^*
GlycoBIST: A System for Automatic Glycan Profiling of a Target Protein Using Milli-Bead Array in a Tip
Curr Protoc Protein Sci. 99: e103 (2020) doi:10.1002/cpps.103
Wagatsuma T, Nagai-Okatani C^#, Matsuda A, Masugi Y, Imaoka M, Yamazaki K, Sakamoto M, Kuno A^*
Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets
Frontiers In Oncology 10: 338 (2020) doi:10.3389/fonc.2020.00338
Zou X, Yao F, Yang F, Zhang F, Xu ZJ, Shi JJ, Kuno A, Zhao H, Zhang Y
Glycomic Signatures of Plasma IgG Improve Preoperative Prediction of the Invasiveness of Small Lung Nodules
Molecules 25: 28 (2020) doi: 10.3390/molecules25010028
Huang GL, Li Z, Li YQ, Liu G, Sun SJ, Gu JG, Kameyama A, Li WZ, Dong WJ
Loss of core fucosylation in both ST6GAL1 and its substrate enhances glycoprotein sialylation in mice
Biochem. J. 477 477: 1179-1201 (2020) doi: 10.1042/BCJ20190789
Baba T, Takagi T, Sumaru K, Kanamori T
Effect of the fluorination degree of partially fluorinated octyl-phosphocholine surfactants on their interfacial properties and interactions with purple membrane as a membrane protein model
Chemistry And Physics Lipids 227 0: 0 (2020) doi:10.1016/j.chemphyslip.2020.104870
Matsuzawa T, Kameyama A, Yaoi K
Identification and characterization of alpha-xylosidase involved in xyloglucan degradation in Aspergillus oryzae
Applied Microbiology And Biotechnology 104 104: 201-210 (2020) doi: 10.1007/s00253-019-10244-z
Takayama Y, Kushige H, Akagi Y, Suzuki Y, Kumagai Y, Kida YS^*
Selective induction of Human Autonomic neurons enables precise control of cardiomyocyte Beating
Sci Rep. 10: 9464 (2020)doi:10.1038/s41598-020-66303-3
Mori N, Akagi Y, Imai Y, Takayama Y, Kida YS^*
Fabrication of Perfusable Vascular Channels and Capillaries in 3D Liver-like Tissue
Sci Rep. 10: 5646 (2020) doi: 10.1038/s41598-020-62286-3
Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development
Altex. 12: 0 (2020) doi: 10.14573/altex.2001241
Arakawa H, Sugiura S, Kawanishi T, Shin K, Toyoda H, Satoh T, Sakai Y, Kanamori T, Kato Y
Kinetic analysis of sequential metabolism of triazolam and its extrapolation to humans using an entero-hepatic two-organ microphysiological system
Lab Chip. 3: 25 (2020) doi: 10.1039/c9lc00884e
Haramoto Y^＃, Onuma Y^＃, Mawaribuchi S, Nakajima Y, Aiki Y, Higuchi K, Shimizu M, Tateno H, Hirabayashi J, Ito Y.
A technique for removing tumourigenic pluripotent stem cells using rBC2LCN lectin.
Regen Ther. 14: 306-314 (2020) doi: 10.1016/j.reth.2020.03.017
Tateno H^*
Expression and Purification of a Human Pluripotent Stem Cell-Specific Lectin Probe, rBC2LCN
Methods Mol Biol. 9084: 30080-8 (2020) doi: 10.1007/978-1-0716-0430-4_44
Mawaribuchi S, Haramoto Y, Tateno H, Onuma Y, Aiki Y, Ito Y
rBC2LCN lectin as a potential probe of early-stage HER2-positive breast carcinoma
FEBS Open Bio 10: 1056-1064 (2020) doi: 10.1002/2211-5463.12852
Giron LB, Tanes CE, Schleimann MH, Engen PA, Mattei LM, Anzurez A, Damra M, Zhang HJ, Bittinger K, Bushman F, Kossenkov A, Denton PW, Tateno H, Keshavarzian A, Landay AL, Abdel-Mohsen M
Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection
Mucosal Immunology 129: 215-222 (2020) doi: 10.1038/s41385-020-0279-5
Giron LB, Papasavvas E, Azzoni L, Yin XF, Anzurez A, Damra M, Mounzer K, Kostman JR, Sanne I, Firnhaber CS, Tateno H, Liu Q, Montaner LJ, Abdel-Mohsen M
Plasma and antibody glycomic biomarkers of time to HIV rebound and viral setpoint
Aids 34 34: 681-686 (2020) doi: 10.1097/QAD.0000000000002476
Tateno H^*, Hiemori K, Minoshima F, Kiyoi K, Matoba K, Katayama J, Kumada Y
Oriented immobilization of rBC2LCN lectin for highly sensitive detection of human pluripotent stem cells using cell culture supernatants
J Biosci Bioeng. 129: 215-222 (2020) doi: 10.1016/j.jbiosc.2019.08.003
Ogita Y^＃, Mawaribuchi S^＃, Nakasako K, Tamura K, Matsuda M, Katsumura T, Oota H, Watanabe G, Yoneda S, Takamatsu N, Ito M
Parallel Evolution of Two dmrt1-Derived Genes, dmy and dm-W, for Vertebrate Sex Determination
iScience 23: 100757 (2020) doi: 10.1016/j.isci.2019.100757
Kimura Y, Yasuno R, Watanabe M, Kobayashi M, Iwaki T, Fujimura C, Ohmiya Y, Yamakage K, Nakajima Y, Kobayashi M, Mashimo N, Takagi Y, Omori T, Corsini E, Germolec D, Inoue T, Rogen EL, Kojima H, Aiba S
An international validation study of the IL-2 Luc assay for evaluating the potential immunotoxic effects of chemicals on T cells and a proposal for reference data for immunotoxic chemicals
Toxicol In Vitro 66: 104832 (2020) doi: 10.1016/j.tiv.2020.104832
Prapaipat K, Saiki P, Bhusita, W, Supatjaree R, Thanchanok M, Nantana B, Weerasak, T
Probiotic property and biological activities of Bifidobacterium animalis subsp. lactis TISTR 2591 isolated from Thai population.
WJARR 5: 149-162 (2020) doi: 10.30574/wjarr.2020.5.3.0072
Hashimoto T, Kozone I, Hashimoto J, Ueoka R, Kagaya N, Fujie M, Sato N, Ikeda H, Shin-ya K
Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908
J. Antibiotics 73: 171-174 (2020) doi: 10.1038/s41429-019-0265-x
Okauchi H, Higo-Yamamoto S, Sowa T, Oike H, Yamamoto S, Wada N, Sakamoto K, Oishi K
Chronically skipping breakfast impairs hippocampal memory-related gene expression and memory function accompanied by reduced wakefulness and body temperature in mice
Biochem Biophys Res Commun. 524: 129-134 (2020) doi: 10.1016/j.bbrc.2020.01.077
Oishi K, Okauchi H, Yamamoto S, Higo-Yamamoto S
Dietary natural cocoa ameliorates disrupted circadian rhythms in locomotor activity and sleep-wake cycles in mice with chronic sleep disorders caused by psychophysiological stress
Nutrition. 75-76: 110751 (2020) doi: 10.1016/j.nut.2020.110751
Hashimoto T, Kozone I, Hashimoto J, Suenaga H, Fujie M, Satoh N, Ikeda H, Shin-Ya K
Identification, Cloning and Heterologous Expression of Biosynthetic Gene Cluster for Desertomycin
J Antibiot. (2020) doi: 10.1038/s41429-020-0319-0
Maruyama C, Chinone Y, Sato S, Kudo F, Ohsawa K, Kubota J, Hashimoto J, Kozone I, Doi T, Shin-Ya K, Eguchi T, Hamano Y
C-Methylation of S-adenosyl-L-Methionine Occurs Prior to Cyclopropanation in the Biosynthesis of 1-Amino-2-Methylcyclopropanecarboxylic Acid (Norcoronamic Acid) in a Bacterium
Biomolecules 10: E775 (2020) doi: 10.3390/biom10050775
Jo T, Nishikori M, Kogure Y, Arima H, Sasaki K, Sasaki Y, Nakagawa T, Iwai F, Momose S, Shiraishi A, Kiyonari H, Kagaya N, Onuki T, Shin-Ya K, Yoshida M, Kataoka K, Ogawa S, Iwai K, Takaori-Kondo A.
LUBAC Accelerates B-cell Lymphomagenesis by Conferring B Cells Resistance to Genotoxic Stress
Blood (2020) doi:10.1182/blood.2019002654
Kawahara T, Itoh M, Izumikawa M, Kagaya N, Sakata N, Tsuchida T, Shin-Ya K
New phenylspirodrimane metabolites MBJ-0030, MBJ-0031, and MBJ-0032 isolated from the soil fungal strain Stachybotrys sp. f23793
Biosci Biotechnol Biochem.(2020) doi: 10.1080/09168451.2020.1757402
Chen MH, Ishizaka M, Narai S, Horitani M, Shigi N, Yao M, Tanaka Y
The [4Fe-4S] cluster of sulfurtransferase TtuA desulfurizes TtuB during tRNA modification in Thermus thermophilus
Commun Biol. 3: 168 (2020) doi: 10.1038/s42003-020-0895-3
Shigi N, Horitani M, Miyauchi K, Suzuki T, Kuroki M
An ancient type of MnmA protein is an iron-sulfur cluster-dependent sulfurtransferase for tRNA anticodons
RNA 26: 240-250 (2020) doi: 10.1261/rna.072066.119
Manabe T, Yasuda H, Terai H, Kagiwada H, Hamamoto J, Ebisudani T, Kobayashi K, Masuzawa K, Ikemura S, Kawada I, Hayashi Y, Fukui K, Horimoto K, Fukunaga K, Soejima K
IGF2 Autocrine-Mediated IGF1R Activation Is a Clinically Relevant Mechanism of Osimertinib Resistance in Lung Cancer
Molecular Cancer Res. 18 18: 549-559 (2020) doi:10.1158/1541-7786.MCR-19-0956
Koiwai K, Inaba K, Morohashi K, Enya S, Arai R, Kojima H, Okabe T, Fujikawa Y, Inoue H, Yoshino R, Hirokawa T, Kato K, Fukuzawa K, Shimada-Niwa Y, Nakamura A, Yumoto F, Senda T, Niwa R
An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo
J Biol Chem. 0: 0 (2020) doi: 10.1074/jbc.RA119.011463
Kagamu H, Kitano S, Yamaguchi O, Yoshimura K, Horimoto K, Kitazawa M, Fukui K, Shiono A, Mouri A, Nishihara F, Miura Y, Hashimoto K, Murayama Y, Kaira K, Kobayashi K
CD4(+) T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy
Cancer Immunology Res. 8 8: 334-344 (2020) doi:10.1158/2326-6066.CIR-19-0574
Adachi K, Yamada T, Ishizuka H, Oki M, Tsunogae S, Shimada N, Chiba O, Orihara T, Hidaka M, Hirokawa T, Odagi M, Konoki K, Yotsu-Yamashita M, Nagasawa K
Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels
Chemistry. 26: 2025-2033 (2020) doi: 10.1002/chem.201904184
Kitazawa M, Hatta T, Sasaki Y, Fukui K, Ogawa K, Fukuda E, Goshima N, Okita N, Yamada Y, Nakagama H, Natsume T, Horimoto K
Promotion of the Warburg effect is associated with poor benefit from adjuvant chemotherapy in colorectal cancer
Cancer Sci. 111: 658-666 (2020) doi: 10.1111/cas.14275
Tokunaga Y, Takeuchi K^*, Okude J, Ori K, Torizawa T, Shimada I^*
Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via (15)N Direct Detection Nuclear Magnetic Resonance
J Med Chem. 12: 0 (2020) doi:10.1021/acs.jmedchem.0c00231
Fukuda T, Hamaguchi M, Osaka T, Hashimoto Y, Ushigome E, Asano M, Yamazaki M, Fukuda E, Yamaguchi K, Ogawa K, Goshima N, Fukui M
A Pilot Study on the Effect of Anti-Thrombopoietin Antibody on Platelet Count in Patients with Type 2 Diabetes
Molecules. 25: 0 (2020) doi:10.3390/molecules25071667
Murano K, Iwasaki YW, Ishizu H, Mashiko A, Shibuya A, Kondo S, Adachi S, Suzuki S, Saito K, Natsume T, Siomi MC, Siomi H
Nuclear RNA export factor variant initiates piRNA-guided co-transcriptional silencing
EMBO JOURNAL 0: 0 (2020) doi:10.15252/embj.2019102870
Otsuka H, Fukao A, Tomohiro T, Adachi S, Suzuki T, Takahashi A, Funakami Y, Natsume T, Yamamoto T, Duncan KE, Fujiwara T
ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism
Biochimie. 9084: 30080-8 (2020) doi: 10.1016/j.biochi.2020.04.010
Goldshtein M, Mellul M, Deutch G, Imashimizu M,Takeuchi K, Meshorer E, Ram O, Lukatsky DB
Transcription Factor Binding in Embryonic Stem Cells Is Constrained by DNA Sequence Repeat Symmetry
Biophysical J. 118 118: 2015-2026 (2020) doi:10.1016/j.bpj.2020.02.009
Tatebayashi K, Yamamoto K, Tomida T, Nishimura A, Takayama T, Oyama M, Kozuka-Hata H, Adachi-Akahane S, Tokunaga Y, Saito H
Osmostress enhances activating phosphorylation of Hog1 MAP kinase by mono-phosphorylated Pbs2 MAP2K
EMBO JOURNAL 39 39: 0 (2020) doi:10.15252/embj.2019103444
Yoshida M, Saito M, Ito S, Ogawa K, Goshima N, Nagata K, Doi T
Structure-Activity Relationship Study on Col-003, a Protein-Protein Interaction Inhibitor between Collagen and Hsp47
Chem Pharm Bull 68: 220-226 (2020) doi:10.1248/cpb.c19-00634
Tokunaga Y, Viennet T, Arthanari H, Takeuchi K^*
Spotlight on the Ballet of Proteins: The Structural Dynamic Properties of Proteins Illuminated by Solution NMR
INTERNATIONAL J. Molecular Sciences 21 21: 0 (2020) doi:10.3390/ijms21051829
Ninomiya K, Adachi S, Natsume T, Iwakiri J, Terai G, Asai K, Hirose T
LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation
EMBO JOURNAL 39 39: 0 (2020) doi:10.15252/embj.2019102729
Asano T, Noda Y, Tanaka KI, Yamakawa N, Wada M, Mashimo T, Fukunishi Y, Mizushima T, Takenaga M
A2B adenosine receptor inhibition by the dihydropyridine calcium channel blocker nifedipine involves colonic fluid secretion
Sci Rep. 10: 3555 (2020) doi:10.1038/s41598-020-60147-7
Taniue K, Hayashi T, Kamoshida Y, Kurimoto A, Takeda Y, Negishi L, Iwasaki K, Kawamura Y, Goshima N, Akiyama T
UHRF1-KAT7-mediated regulation of TUSC3 expression via histone methylation/acetylation is critical for the proliferation of colon cancer cells
Oncogene 39 39: 1018-1030 (2020) doi:10.1038/s41388-019-1032-y
Yasuda R, Adachi S, Okonogi A, Anzai Y, Kamiyama T, Katano K, Hoshi N, Mogi K, Natsume T
Cell Stress Reduction by a Novel Perfusion-Culture System Using Commercial Culture Dish
Applied Sciences-Basel 10 10: 0 (2020) doi:10.3390/app10010095
Kumar V, Dhanjal JK, Bhargava P, Kaul A, Wang J, Zhang H, Kaul SC, Wadhwa R, Sundar D.
Withanone and withaferin-A Are Predicted to Interact with Transmembrane Protease Serine 2 (TMPRSS2) and Block Entry of SARS-CoV-2 Into Cells
J Biomol Struct Dyn. 1-27 (2020) doi:10.1080/07391102.2020.1775704
Kumar V, Dhanjal JK, Kaul SC, Wadhwa R, Sundar D.
Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity
J Biomol Struct Dyn 1-13 (2020) doi:10.1080/07391102.2020.1772108
Kim H, Hoshi M, Iijima M, Kuroda S, Nakamura C
Development of a universal method for the measurement of binding affinities of antibody drugs towards a living cell based on AFM force spectroscopy
Anal Methods (2020) doi:10.1039/d0ay00788a
Sari AN, Bhargava P, Dhanjal JK, Putri JF, Radhakrishnan N, Shefrin S, Ishida Y, Terao K, Sundar D, Kaul SC, Wadhwa R
Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action
Cancers 12(5): E1160 (2020). doi:10.3390/cancers12051160
Omar A, Kalra RS, Putri J, Elwakeel A, Kaul SC, Wadhwa R
Soyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells
Sci Rep. 10: 6323 (2020) doi:10.1038/s41598-020-62953-5
Kalra RS, Chaudhary A, Omar A, Cheung CT, Garg S, Kaul SC, Wadhwa R
Stress-induced changes in CARF expression determine cell fate to death, survival, or malignant transformation
Cell Stress Chaperones 25(3): 481-494 (2020). doi:10.1007/s12192-020-01088-y
Kurinomaru T, Inagaki A, Hoshi M, Nakamura C, Yamazoe H
Protein microswimmers capable of delivering cells for tissue engineering applications
Materials Horizons 7 7: 877-884 (2020) doi::10.1039/c9mh01799b
Afzal S, Garg S, Adiga D, Ishida Y, Terao K, Kaul SC, Wadhwa R
Anti-stress, Glial- and Neuro-differentiation Potential of Resveratrol: Characterization by Cellular, Biochemical and Imaging Assays
Nutrients 12(3): 671 (2020). doi: :10.3390/nu12030671
Kim H, Ishibashi K, Okada T, Nakamura C
Adhesion strengths between cancer cells with different malignancies and endothelial cells measured using atomic force microscopy
Jpn J Appl Phys 59: SDDE01 (2020) doi: 10.7567/1347-4065/ab51ad
Garg S, Huifu H, Kumari A, Sundar D, Kaul SC, Wadhwa R
Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential
J Gerontol A Biol Sci Med Sci. 75(6):1031-1041 (2020). doi: 10.1093/gerona/glz077
Ninomiya H, Intoh A, Ishimine H, Onuma Y, Ito Y, Michiue T, Tazaki A, Kato M
Application of a human mesoderm tissue elongation system in vitro derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals
Chemosphere 250 :126124 (2020) doi: 10.1016/j.chemosphere.2020.126124
Yoshimura Y, Nagashima I, Yokoe T, Kishimoto T, Shimizu H, Chiba Y
A new strategy for the chemoenzymatic synthesis of glycopeptides by De-O-acetylation with an esterase and glycosylations with glycosyltransferases
Carbohydr Res. 0: 0 (2020) doi: 10.1016/j.carres.2020.108023
Akita S, Yamaji Y, Takeuchi N, Wakai K, Azuma K, Nakagawa A, Fujimoto H, Sangai T, Nagashima T, Mitsukawa N, Ikehara Y
Detection of Nonpalpable Tiny Axillary Lymph Nodes Surrounded by Adipose Tissue Using a Near-Infrared Camera
Lymphatic Res. And Biology 39: 0 (2020) doi: 10.1089/lrb.2019.0022
Nakakita SI, Sriwilaijaroen N, Suzuki Y, Hirabayashi J
Preparation and Detection of Glycan-Binding Activity of Influenza Virus
Methods Mol Biol. 9084: 30080-8 (2020) doi: 10.1007/978-1-0716-0430-4_49
Akazawa-Ogawa Y, Komatsu Y, Nakajima Y, Kojima N, Hagihara Y
PCR-based approach for site-specific conjugation of long double-stranded DNA to a single-domain VHH antibody
J Biochem. 0: 0 (2020) doi: 10.1093/jb/mvaa029
Echizenya S, Ishii Y, Kitazawa S, Tanaka T, Matsuda S, Watanabe E, Umekawa M, Terasaka S, Houkin K, Hatta T, Natsume T, Maeda Y, Watanabe S, Hagiwara S, Kondo T
Discovery of a new pyrimidine synthesis inhibitor eradicating glioblastoma-initiating cells
Neuro-Oncology 22 22: 229-239 (2020) doi: 10.1093/neuonc/noz170
Oyane A, Araki H, Nakamura M, Aiki Y, Higuchi K, Pyatenko A, Adachi M, Ito Y
Controlled release of basic fibroblast growth factor from a water-floatable polyethylene nonwoven fabric sheet for maintenance culture of iPSCs
Rsc Advances 10: 95-104 (2020) doi: 10.1039/c9ra06906b
Yamada H, Kato S, Shimizu T, Fujiwara M, Fujiwara Y, Kim J, Ikehara S, Shimizu N, Ikehara Y, and Sakakita H.
Striation phenomena in a low temperature atmospheric pressure neon plasma jet by optical emission spectroscopy.
Physics of Plasmas 27, 022107, 2020 doi: 10.1063/1.5124122

2019年

Holdener BC, Percival CJ, Grady RC, Cameron DC, Berardinelli SJ, Zhang A, Neupane S, Takeuchi M, Jimenez-Vega JC, Uddin SMZ, Komatsu DE, Honkanen R, Dubail J, Apte SS, Sato T, Narimatsu H, McClain SA, Haltiwanger RS.
ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome. Hum Mol Genet. 28: 4053-4066 (2019).doi: 10.1093/hmg/ddz225
Kurata I, Matsumoto I, Ohyama A, Osada A, Ebe H, Kawaguchi H, Kaneko S, Kondo Y, Tsuboi H, Tomioka A, Kaji H, Sumida T
Potential involvement of OX40 in the regulation of autoantibody sialylation in arthritis
Ann Rheum Dis. 78: 1488-1496 (2019) doi: 10.1136/annrheumdis-2019-215195
Nagai-Okatani C^#*, Nishigori M, Sato T, Minamino N, Kaji H, Kuno A^*
Wisteria floribunda agglutinin staining for the quantitative assessment of cardiac fibrogenic activity in a mouse model of dilated cardiomyopathy
Lab Invest. 99: 1749-1765 (2019) doi: 10.1038/s41374-019-0279-9
Shimazaki H, Saito K, Matsuda A, Sawakami K, Kariya M, Segawa O, , Miyashita Y, Ueda T, Koizuka M, Nakamura K, Kaji H, Tajima H, , Kuno A^*
Lectin Bead Array in a Single Tip Facilitates Fully Automatic Glycoprotein Profiling
Anal Chem.91: 11162-11169 (2019) doi: 10.1021/acs.analchem.9b01876
Saku A, Hirose K, Ito T, Iwata A, Sato T, Kaji H, Tamachi T, , Suto A, Goto Y, Domino SE, Narimatsu H, Kiyono H, Nakajima H
Fucosyltransferase 2 induces lung epithelial fucosylation and exacerbates house dust mite-induced airway inflammation
J. Allergy Clin Immunol. 144: 698-709 (2019) doi: 10.1016/j.jaci.2019.05.010
Takahama H, Nishikimi T, Takashio S, Hayashi T, Nagai-Okatani C, Asada T, Fujiwara A, Nakagawa Y, Amano M, Hamatani Y, Okada A, Amaki M, Hasegawa T, Kanzaki H, Nishimura K, Yasuda S, Kangawa K, Anzai T, Minamino N, Izumi C.
Change in the NT-proBNP/Mature BNP Molar Ratio Precedes Worsening Renal Function in Patients With Acute Heart Failure: A Novel Predictor Candidate for Cardiorenal Syndrome
J Am Heart Assoc. 8: e011468 (2019). doi: 10.1161/JAHA.118.011468
Nagai-Okatani C^#, Aoki-Kinoshita KF, Kakuda S, Nagai M, Hagiwara K, Kiyohara K, Fujita N, Suzuki Y, Sato T, Angata K, Kuno A^*
LM-GlycomeAtlas Ver. 1.0: A Novel Visualization Tool for Lectin Microarray-Based Glycomic Profiles of Mouse Tissue Sections
Molecules. 24: 2962 (2019) doi: 10.3390/molecules24162962
Takashio S, Takahama H, Nishikimi T, Hayashi T, Nagai-Okatani C, Matsuo A, Nakagawa Y, Amano M, Hamatani Y, Okada A, Amaki M, Hasegawa T, Kanzaki H, Yasuda S, Kangawa K, Anzai T, Minamino N, Izumi C.
Superiority of Proatrial Natriuretic Peptide in the Prognostic Power in Patients With Acute Decompensated Heart Failure on Hospital Admission: Comparison With B-type Natriuretic Peptide and Other Natriuretic Peptide Forms
Open Geart. 6: e001072 (2019). doi: 10.1136/openhrt-2019-001072
Nakane T, Angata K, Sato T, Kaji H, Narimatsu H
Identification of mammalian glycoproteins with type-I LacdiNAc structures synthesized by the glycosyltransferase B3GALNT2
J Biol Chem. 294: 7433-7444 (2019) doi: 10.1074/jbc.RA118.006892
Shan A, Lu J, Xu Z, Li X, Xu Y, Li W, Liu F, Yang F, Sato T, Narimatsu H, Zhang Y.
Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation.
Biochim Biophys Acta Gen Subj. 1863: 870-882 (2019). doi: 10.1016/j.bbagen.2019.01.009
Nagai-Okatani C^#, Nagai M, Sato T, Kuno A^*
An Improved Method for Cell Type-Selective Glycomic Analysis of Tissue Sections Assisted by Fluorescence Laser Microdissection
Int J Mol Sci. 20: 700 (2019) doi: 10.3390/ijms20030700
Shirabe K, Bekki Y, Gantumur D, Araki K, Ishii N, Kuno A, Narimatsu H, Mizokami M
Response to the letter by Dr. Naoya Yamada, and Dr. Koichi Mizuta regarding our manuscript
J Gastroenterol. 54 : 206-207 (2019) doi: 10.1007/s00535-018-1524-5
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榊田　創、池原　譲
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An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
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Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex
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Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock
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BDNF Binds Its Pro-Peptide with High Affinity and the Common Val66Met Polymorphism Attenuates the Interaction
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Discovery of Novel Indazole Derivatives as Orally Available beta(3)-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects
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Analysis of Autoantibodies Related to Tumor Progression in Sera from Patients with High-grade Non-muscle-invasive Bladder Cancer
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Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle
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Determination of Rate-Limiting Factor for Formation of Beta-Catenin Destruction Complexes Using Absolute Protein Quantification
J Proteome Res. 16: 3576-3584 (2017) doi: 10.1021/acs.jproteome.7b00305
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Forbidden Coherence Transfer of (19)F Nuclei to Quantitatively Measure the Dynamics of a CF(3)-Containing Ligand in Receptor-Bound States
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Live imaging of X chromosome inactivation and reactivation dynamics
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The crystal structure of a new O-demethylase from Sphingobium sp strain SYK-6
FEBS JOURNAL 284: 1855-1867 (2017) doi: 10.1111/febs.14085
Yamamoto M, Sakane K, Tominaga K, Gotoh N, Niwa T, Kikuchi Y, Tada K, Goshima N, Semba K, Inoue JI
Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer
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Ihara T, Hosokawa Y, Kumazawa K, Ishikawa K, Fujimoto J, Yamamoto M, Muramkami T, Goshima N, Ito E, Watanabe S, Semba K
An in vivo screening system to identify tumorigenic genes
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Vacuum ultraviolet light assisted bonding and nanoscale pattern transfer method for polydimethylsiloxane．
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Kawamura R, Miyazaki M, Shimizu K, Matsumoto Y, Silberberg YR, Sathuluri RR, Iijima M, Ruroda S, Iwata F, Kobayashi T, Nakamura C
A New Cell Separation Method Based on Antibody-Immobilized Nanoneedle Arrays for the Detection of Intracellular Markers
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Chaudhary A, Kalra RS, Huang C, Prakash J, Kaul SC, Wadhwa R
2,3-Dihydro-3beta-methoxy Withaferin-A Protects Normal Cells against Stress: Molecular Evidence of Its Potent Cytoprotective Activity
J Nat Prod. 80: 2756-2760 (2017) doi: 10.1021/acs.jnatprod.7b00573
Lee WJ, Ahn HM, Na Y, Wadhwa R, Hong J, Yun CO
Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids
Sci Rep. 7(1):12957(2017) doi: 10.1038/s41598-017-13485-y
Putri JF, Widodo N, Sakamoto K, Kaul SC, Wadhwa R
Induction of senescence in cancer cells by 5-Aza-2-deoxycytidine: Bioinformatics and experimental insights to its targets
Comput Biol Chem. 125: 168-174 (2017) doi: 10.1016/j.compbiolchem.2017.08.003
Wadhwa R, Kalra RS, Kaul SC
CARF is a multi-module regulator of cell proliferation and a molecular bridge between cellular senescence and carcinogenesis
Mech Ageing Dev. 14: 3025-3035 (2017) doi: 10.1016/j.mad.2017.07.008
Kim H, Yamagishi A, Imaizumi M, Onomura Y, Nagasaki A, Miyagi Y, Okada T, Nakamura C
Quantitative measurements of intercellular adhesion between a macrophage and cancer cells using a cup-attached AFM chip
Colloids Surf B Biointerfaces 37: 366-372 (2017) doi: 10.1016/j.colsurfb.2017.04.039
Girault M, Kim H, Arakawa H, Matsuura K, Odaka M, Hattori A, Terazono H, Yasuda K
An on-chip imaging droplet-sorting system: a real-time shape recognition method to screen target cells in droplets with single cell resolution
Sci Rep 7: 40072 (2017) doi: 10.1038/srep40072
Nishio M, Matsumoto D, Kato Y, Abe K, Lee J, Tsukakoshi K, Yamagishi A, Nakamura C, Ikebukuro K
DNA aptamers against FokI nuclease domain for genome editing applications
Biosens. Bioelectron. 93: 26-31 (2017) doi: 10.1016/j.bios.2016.11.042
Tomita T, Kurita R, Onishi Y
Epigenetic regulation of the circadian clock: role of 5-aza-2-deoxycytidine
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Nagasaki A, T Kijima S, Yumoto T, Imaizumi M, Yamagishi A, Kim H, Nakamura C, Q P Uyeda T
The Position of the GFP Tag on Actin Affects the Filament Formation in Mammalian Cells
Cell Struct Funct. 42: 131-140 (2017) doi: 10.1247/csf.17016
Singh P, Guleri R, Angurala A, Kaur K, Kaur K, Kaul SC, Wadhwa R, Pati PK
Addressing Challenges to Enhance the Bioactives of Withania somnifera through Organ, Tissue, and Cell Culture Based Approaches
Biomed Res Int. 486: 539-544 (2017) doi: 10.1155/2017/3278494
Yu Y, Katiyar SP, Sundar D, Kaul Z, Miyako E, Zhang Z, Kaul SC, Reddel RR, Wadhwa R
Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences
Cell Death Dis. 8(4): e2755 (2017). doi: 10.1038/cddis.2017.33
Yun CO, Bhargava P, Na Y, Lee JS, Ryu J, Kaul SC, Wadhwa R
Relevance of Mortalin to Cancer Cell Stemness and Cancer Therapy
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Ogawa T, Hirohashi Y, Murai A, Nishidate T, Okita K, Wang L, Ikehara Y, Satoyoshi T, Usui A, Kubo T, Nakastugawa M, Kanaseki T, Tsukahara T, Kutomi G, Furuhata T, Hirata K, Sato N, Mizuguchi T, Takemasa I, Torigoe T
ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway
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Hirata Y, Katagiri K, Nagaoka K, Morishita T, Kudoh Y, Hatta T, Naguro I, Kano K, Udagawa T, Natsume T, Aoki J, Inada T, Noguchi T, Ichijo H, Matsuzawa A
TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1
Cell Rep. 21: 2447-2457 (2017) doi: 10.1016/j.celrep.2017.11.007
Matsudaira T, Mukai K, Noguchi T, Hasegawa J, Hatta T, Iemura SI, Natsume T, Miyamura N, Nishina H, Nakayama J, Semba K, Tomita T, Murata S, Arai H, Taguchi T
Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells
Nat Commun. 8: 1246 (2017) doi: 10.1038/s41467-017-01255-3
Chowdhury AMMA, Katoh H, Hatanaka A, Iwanari H, Nakamura N, Hamakubo T, Natsume T, Waku T, Kobayashi A
Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation
Sci Rep. 7: 12494 (2017) doi: 10.1038/s41598-017-12675-y
Shimizu T, Watanabe K, Anayama N, Miyazaki K
Effect of lipopolysaccharide on circadian clock genes Per2 and Bmal1 in mouse ovary
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Suzuki T, Baba S, Ono M, Nonaka K, Ichikawa K, Yabuta M, Ito R, Chiba Y
Efficient antibody production in the methylotrophic yeast Ogataea minuta by overexpression of chaperones.
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Fujimori T, Suno R, Iemura SI, Natsume T, Wada I, Hosokawa N
Endoplasmic reticulum proteins SDF2 and SDF2L1 act as components of the BiP chaperone cycle to prevent protein aggregation
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Chronic sleep fragmentation exacerbates amyloid beta deposition in Alzheimers disease model mice
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Effect of plasma-activated medium on the decrease of tumorigenic population in lymphoma
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uzuki T, Imada T, Komatsu Y, Kamiya H
Comparison of DNA fragments as donor DNAs upon sequence conversion of cleaved target DNA
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Loss of Parkinsons disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c
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Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion
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Ikehara S, Miyamoto K, Ikehara Y, Sakakita H
Low temperature plasma equipment applied on surgical hemostasis and wound healings
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Montagne K, Onuma Y, Ito Y, Aiki Y, Furukawa KS, Ushida T
High hydrostatic pressure induces pro-osteoarthritic changes in cartilage precursor cells: A transcriptome analysis
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Murugan V, Parasuraman P, Selvin JFA, Gromiha MM, Fukui K, Veluraja K
Theoretical investigation on the binding specificity of fluorinated sialyldisaccharides Neu5Ac(2-3)Gal and Neu5Ac(2-6)Gal with influenza hemagglutinin H1-A Molecular Dynamics Study
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Yachie N, Natsume T
Robotic crowd biology with Maholo LabDroids
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