研究成果
誌上発表
2023年
- Odaka, H; Tateno, H.
Single-Cell Glycan and RNA Sequencing (scGR-seq).
CURR PROTOC. 2023 May;3(5):e777. doi: 10.1002/cpz1.777
- Arima, K; Akiyama, S; Shin-Ya, K; Matsuda, K; Wakimoto, T.
Carrier Protein Mediated Formation of the Dihydropyridazinone Ring in Actinopyridazinone Biosynthesis.
ANGEW CHEM INT ED ENGL. 2023 May 17:e202305155. doi: 10.1002/anie.202305155
- Huifu, H; Shefrin, S; Yang, S; Zhang, Z; Kaul, SC; Sundar, D; Wadhwa, R.
Cucurbitacin-B inhibits cancer cell migration by targeting mortalin and HDM2: computational and in vitro experimental evidence.
J BIOMOL STRUCT DYN. 2023 May 2:1-10. doi: 10.1080/07391102.2023.2206914
- Nakagawa, Y; Hishida, T; Sumaru, K; Morishita, K; Kirito, K; Yokojima, S; Sakamoto, Y; Nakamura, S; Uchida, K.
Phototunable Cell Killing by Photochromic Diarylethene of Thiazoyl and Thienyl Derivatives.
JOURNAL OF MEDICINAL CHEMISTRY. 2023, 66 (8) 5937-5949. doi: 10.1021/acs.jmedchem.3c00164
- Kumagai, Y; Saito, Y; Kida, YS.
A multiomics atlas of brown adipose tissue development over time.
ENDOCRINOLOGY. 2023 Apr 21:bqad064. doi: 10.1210/endocr/bqad064
- Zhang, H; Wang, J; Prakash, J; Zhang, Z; Kaul, SC; Wadhwa, R.
Three-way Cell-based Screening of Antistress Compounds: Identification, Validation, and Relevance to Old-age Related Pathologies.
J GERONTOL A BIOL SCI MED SCI. 2023 Apr 15:glad103. doi: 10.1093/gerona/glad103
- Sugiura, T; Hashimoto, K; Kikuta, K; Anazawa, U; Nomura, T; Kameyama, A.
Expression and localisation of MUC1 modified with sialylated core-2 O-glycans in mucoepidermoid carcinoma.
SCI REP. 2023 Apr 8;13(1):5752. doi: 10.1038/s41598-023-32597-2
- Ikemoto, MJ; Aihara, Y; Ishii, N; Shigemori, H.
3,4-Dihydroxybenzalacetone Inhibits the Propagation of Hydrogen Peroxide-Induced Oxidative Effect via Secretory Components from SH-SY5Y Cells.
BIOL PHARM BULL. 2023;46(4):599-607. doi: 10.1248/bpb.b22-00727
2022年
- Sugiura, S; Yamahira, S; Tamura, M; Shin, K; Shibuta, M; Satoh, T; Matsuzawa, Y; Fujii, G; Yanagawa, F; Mutoh, M; Yanagisawa, M; Kato, R; Matsui, H.
Automated cell isolation from photodegradable hydrogel based on fluorescence image analysis.
BIOTECHNOL BIOENG. 2023 Mar 15. doi: 10.1002/bit.28375
- Murata, Y; Jitsukawa, T; Iida, M; Furuta, T; Haramoto, Y; Shigeri, Y; Fujisaki, S.
Liquid chromatography-mass spectrometry analyses of polyprenyl phosphates in Escherichia coli cells in which genes for isoprenoid synthesis are amplified.
J BIOSCI BIOENG. 2023 Mar 1:S1389-1723(23)00047-6. doi: 10.1016/j.jbiosc.2023.02.003
- Shin, WH; Kumazawa, K; Imai, K; Hirokawa, T; Kihara, D.
Quantitative comparison of protein-protein interaction interface using physicochemical feature-based descriptors of surface patches.
FRONT MOL BIOSCI. 2023 Feb 6;10:1110567. doi: 10.3389/fmolb.2023.1110567
- Mawaribuchi, S; Ito, M; Ogata, M; Yoshimura, Y; Miura, I.
Parallel Evolution of Sex-Linked Genes across XX/XY and ZZ/ZW Sex Chromosome Systems in the Frog Glandirana rugosa.
GENES (Basel). 2023 Jan 18;14(2):257. doi: 10.3390/genes14020257
- Rangasami, VK; Asawa, K; Teramura, Y; Le, Blanc K; Nilsson, B; Hilborn, J; Varghese, OP; Oommen, OP.
Biomimetic polyelectrolyte coating of stem cells suppresses thrombotic activation and enhances its survival and function.
BIOMATER ADV. 2023 Feb 8;147:213331. doi: 10.1016/j.bioadv.2023.213331
- Sogo, T; Nakao, S; Tsukamoto, T; Ueyama, T; Harada, Y; Ihara, D; Ishida, T; Nakahara, M; Hasegawa, K; Akagi, Y; Kida, YS; Nakagawa, O; Nagamune, T; Kawahara, M; Kawamura, T.
Canonical Wnt signaling activation by chimeric antigen receptors for efficient cardiac differentiation from mouse embryonic stem cells.
INFLAMM REGEN. 2023 Feb 10;43(1):11. doi: 10.1186/s41232-023-00258-6
- Kumar, V; Sari, AN; Meidinna, HN; Kaul, A; Basu, B; Ishida, Y; Terao, K; Kaul, SC; Vrati, S; Sundar, D; Wadhwa, R.
Computational and experimental evidence of the anti-COVID-19 potential of honeybee propolis ingredients, caffeic acid phenethyl ester and artepillin c.
PHYTOTHER RES. 2023 Feb 9. doi: 10.1002/ptr.7717
- Sato, Y; Kato, Y; Iizumi, Y; Morimoto, T; Kobashi, K; Sugino, T; Tateno, H; Okazaki, T.
Size distributions of cellulose nanocrystals in dispersions using the centrifugal sedimentation method.
INT J BIOL MACROMOL. 2023 Feb 2:123520. doi: 10.1016/j.ijbiomac.2023.123520
- Mawaribuchi, S; Shimomura, O; Oda, T; Hiemori, K; Shimizu, K; Yamase, K; Date, M; Tateno, H.
rBC2LCN-reactive SERPINA3 is a glycobiomarker candidate for pancreatic ductal adenocarcinoma.
GLYCOBIOLOGY. 2023 Feb 2:cwad009. doi: 10.1093/glycob/cwad009
- Matsuda, KM; Kotani, H; Yamaguchi, K; Okumura, T; Fukuda, E; Kono, M; Hisamoto, T; Kawanabe, R; Norimatsu, Y; Kuzumi, A; Fukayama, M; Fukasawa, T; Ebata, S; Yoshizaki-Ogawa, A; Okamura, T; Shoda, H; Fujio, K; Goshima, N; Sato, S; Yoshizaki, A.
Significance of anti-transcobalamin receptor antibodies in cutaneous arteritis revealed by proteome-wide autoantibody screening.
J AUTOIMMUN. 2023 Jan 30;135:102995. doi: 10.1016/j.jaut.2023.102995
- Itakura, Y; Hasegawa, Y; Kikkawa, Y; Murakami, Y; Sugiura, K; Nagai-Okatani, C; Sasaki, N; Umemura, M; Takahashi, Y; Kimura, T; Kuno, A; Ishiwata, T; Toyoda, M.
Spatiotemporal changes of tissue glycans depending on localization in cardiac aging.
REGEN THER. 2023 Jan 7;22:68-78. doi: 10.1016/j.reth.2022.12.009
- Huang, T; Sato, Y; Kuramochi, A; Ohba, Y; Sano, M; Miyagishi, M; Tateno, H; Wadhwa, R; Kawasaki, K; Uchida, T; Ekdahl, KN; Nilsson, B; Chung, UI; Teramura, Y.
Surface modulation of extracellular vesicles with cell-penetrating peptide-conjugated lipids for improvement of intracellular delivery to endothelial cells.
REGEN THER. 2023 Jan 11;22:90-98. doi: 10.1016/j.reth.2022.12.007
- Tsuda, M; Nakatani, Y; Baba, S; Tanaka, I; Ichikawa, K; Nonaka, K; Ito, R; Yoko-O, T; Chiba, Y.
Selection of the methylotrophic yeast Ogataea minuta as a high-producing host for heterologous protein expression.
J BIOSCI BIOENG. 2023 Jan 24:S1389-1723(22)00375-9. doi: 10.1016/j.jbiosc.2022.12.006
- Yu, Y; Zhang, GX; Li, ZP; Wang, J; Liu, Y; Bhardwaj, R; Wadhwa, R; Nagao, Y; Shichiri, M; Gao, R.
Designed fabrication of active tumor targeting covalent organic framework nanotherapeutics via a simple post-synthetic strategy.
NANO RESEARCH. 03 January 2023. doi: 10.1007/s12274-022-5265-7
- Ato, S; Matsunami, H;Ogasawara, R.
Aging is associated with impaired postprandial response of skeletal muscle protein synthesis to high-intensity muscle contraction in mice.
J GERONTOL A BIOL SCI MED SCI. 2023 Jan 12:glad014. doi: 10.1093/gerona/glad014
- Mawaribuchi, S; Haramoto, Y; Ikeda, N; Ito, M.
Evolutionary features of ligands and their receptors via protein-protein interactions and essentiality in primates.
GENES CELLS. 2023 Jan 9. doi: 10.1111/gtc.13006
- Kudo, F; Kishikawa, K; Tsuboi, K; Kido, T; Usui, T; Hashimoto, J; Shin-Ya, K; Miyanaga, A; Eguchi, T.
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics.
CHEMBIOCHEM. 2023 Jan 5. doi: 10.1002/cbic.202200670
- Takeda, H; Busto, JV; Lindau, C; Tsutsumi, A; Tomii, K; Imai, K; Yamamori, Y; Hirokawa, T; Motono, C; Ganesan, I; Wenz, LS; Becker, T; Kikkawa, M; Pfanner, N; Wiedemann, N; Endo, T.
A multipoint guidance mechanism for β-barrel folding on the SAM complex.
NAT STRUCT MOL BIOL. 2023 Jan 5. doi: 10.1038/s41594-022-00897-2
- Limjanthong, N; Tohbaru, Y; Okamoto, T; Okajima, R; Kusama, Y; Kojima, H; Fujimura, A; Miyazaki, T; Kanamori, T; Sugiura, S; Ohnuma, K.
Gravity-driven microfluidic device placed on a slow-tilting table enables constant unidirectional perfusion culture of human induced pluripotent stem cells.
J BIOSCI BIOENG. 2022 Dec 29:S1389-1723(22)00346-2. doi: 10.1016/j.jbiosc.2022.11.007
- Ishii, N.
C-shaped dipper: A novel useful auxiliary tool for preparation of specimen grids for transmission electron microscopy.
MICROSC RES TECH. 2022 Dec 29. doi: 10.1002/jemt.24283
- Hayashida, R; Kikuchi, R; Imai, K; Kojima, W; Yamada, T; Iijima, M; Sesaki, H; Tanaka, K; Matsuda, N; Yamano, K.
Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method.
J BIOL CHEM. 2022 Dec 20:102822. doi: 10.1016/j.jbc.2022.102822
- Murotomi, K; Kagiwada, H; Hirano, K; Yamamoto, S; Numata, N; Matsumoto, Y; Kaneko, H; Namihira, M.
Cyclo-glycylproline attenuates hydrogen peroxide-induced cellular damage mediated by the MDM2-p53 pathway in human neural stem cells.
J CELL PHYSIOL. 2022 Dec 31. doi: 10.1002/jcp.30940
- Ishimura, R; El-Gowily, AH; Noshiro, D; Komatsu-Hirota, S; Ono, Y; Shindo, M; Hatta, T; Abe, M; Uemura, T; Lee-Okada, HC; TMohamed, TM; Yokomizo, T; Ueno, T; Sakimura, K; Natsume, T; Sorimachi, H; Inada, T; Waguri, S; Noda, NN; Komatsu, M.
The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
NAT COMMUN. 2022 Dec 21;13(1):7857. doi: 10.1038/s41467-022-35501-0
- Ando, M; Kawasaki, H; Tamura, S; Haramoto, Y; Shigeri, Y.
Recent Advances in Gas Sensing Technology Using Non-Oxide II-VI Semiconductors CdS, CdSe, and CdTe.
CHEMOSENSORS. 2022 10(11)482. doi: 10.3390/chemosensors10110482
- Suzuki, H; Adler, A; Huang, T; Kuramochi, A; Ohba, Y; Sato, Y; Nakamura, N; Manivel, VA; Ekdahl, KN; Nilsson, B; Ishihara, K; Teramura, Y.
Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions.
SCI TECHNOL ADV MATER. 2022 Dec 8;23(1):845-857. doi: 10.1080/14686996.2022.2146466
- Zou, X; Lu, J; Deng, Y; Liu, Q; Yan, X; Cui, Y; Xiao, X; Fang, M; Yang, F; Sawaki, H; Sato, T; Tan, B; Lu, X; Feng, B; Kuno, A; Narimatsu, H; Gao, C; Zhang, Y.
ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface.
ONCOGENE. 2022 Dec 17. doi: 10.1038/s41388-022-02571-9
- Yoshida, Y; Yajima, Y; Fujikura, Y; Zhuang, H; Higo-Yamamoto, S; Toyoda, A; Oishi, K.
Identification of salivary microRNA profiles in male mouse model of chronic sleep disorder.
Stress. 2022;26(1):21-28. doi: 10.1080/10253890.2022.2156783
- Yoshida, Y; Yajima, Y; Kawakami, K; Nakamura, S; Tsukahara, T; Oishi, K; Toyoda, A.
Salivary microRNA and metabolic profiles in a mouse model of subchronic and mild social defeat stress.
Int J Mol Sci. 2022;23:14479. doi: 10.3390/ijms232214479
- Horikawa, K; Hashimoto, C; Kikuchi, Y; Makita, M; Oishi, K.
Wheat alkylresorcinol increases fecal lipid excretion and suppresses feed efficiency in mice depending on the time of supplementation.
Nutrition. 2022;103-104:111796. doi: 10.1016/j.nut.2022.111796
- Ohkura, N; Taniguchi, M; Oishi, K; Inoue, K; Ohta, M.
Angelica keiskei (Ashitaba) has potential as an antithrombotic health food.
Food Res. 2022;6(2):18-24. doi: 10.26656/fr.2017.6(2).121
- Abe, T.
Timing of Medium-Chain Triglyceride Consumption Modulates Effects in Mice with Obesity Induced by a High-Fat High-Sucrose Diet.
NUTRIENTS. 2022 Dec 1;14(23):5096. doi: 10.3390/nu14235096
- Nagashima, I; Sugiyama, JI; Shimizu, H.
Study of 400 MHz microwave conduction loss effect for a hydrolysis reaction by thermostable β-Glucosidase HT1.
BIOSCI BIOTECHNOL BIOCHEM. 2022 Dec 6:zbac194. doi: 10.1093/bbb/zbac194
- Kuroda, Y; Shimomura, O; Nakahashi, H; Miyazaki, Y; Nakajima, T; Tateno, H; Oda, T.
Lectin-based photoimmunotherapy targeting cell surface glycans for pancreatic cancer.
CANCER RESEARCH 82 (22). 2022 NOV 15. doi: 10.1158/1538-7445.PANCA22-B083
- Haji, S; Ito, T; Guenther, C; Nakano, M; Shimizu, T; Mori, D; Chiba, Y; Tanaka, M; Mishra, SK; Willment, JA; Brown, GD; Nagae, M; Yamasaki, S.
Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2.
ELIFE. 2022 Dec 8;11:e83037. doi: 10.7554/eLife.83037
- Fukunishi, Y; Higo, J; Kasahara, K.
Computer simulation of molecular recognition in biomolecular system: from in silico screening to generalized ensembles.
BIOPHYS REV. 2022 Nov 28:1-25. doi: 10.1007/s12551-022-01015-8
- Kudo, F; Minato, A; Sato, S; Nagano, N; Maruyama, C; Hamano, Y; Hashimoto, J; Kozone, I; Shin-Ya; Eguchi, T.
Mechanism of S-Adenosyl-l-methionine C-Methylation by Cobalamin-dependent Radical S-Adenosyl-l-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis.
ORG LETT. 2022 Dec 2. doi: 10.1021/acs.orglett.2c03555
- Kato, K; Okazaki, S; Schmitt-Ulms, C; Jiang, K; Zhou, W; Ishikawa, J; Isayama, Y; Adachi, S; Nishizawa, T; Makarova, KS; Koonin, EV; Abudayyeh, OO; Gootenberg, JS; Nishimasu, H.
RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.
SCIENCE. 2022 Nov 25;378(6622):882-889. doi: 10.1126/science.add7347
- Sugio, Y; Yamagami, R; Shigi, N; Hori, H.
A selective and sensitive detection system for 4-thiouridine modification in RNA.
RNA. 2022 Nov 21:rna.079445.122. doi: 10.1261/rna.079445.122
- Fujikura, Y; Yamanouchi, K; Sugihara, H; Hatakeyama, M; Abe, T; Ato, S; Oishi, K.
Ketogenic diet containing medium-chain triglyceride ameliorates transcriptome disruption in skeletal muscles of rat models of duchenne muscular dystrophy.
BIOCHEM BIOPHYS REP. 2022 Nov 11;32:101378. doi: 10.1016/j.bbrep.2022.101378
- Kuroda, Y; Oda, T; Shimomura, O; Hashimoto, S; Akashi, Y; Miyazaki, Y; Furuya, K; Furuta, T; Nakahashi, H; Louphrasitthiphol, P; Mathis, BJ; Nakajima,T; Tateno, H.
Lectin-based phototherapy targeting cell surface glycans for pancreatic cancer.
INT J CANCER. 2022 Nov 22. doi: 10.1002/ijc.34362
- Lintuluoto, M; Abe, M; Horioka, Y; Fukunishi, Y; Tamura, H; M, Lintuluoto J.
Investigation on substrate specificity and catalytic activity of serine protease neuropsin.
BIOPHYS PHYSICOBIOL. 2022 Sep 22;19:e190040. doi: 10.2142/biophysico.bppb-v19.0040
- Nohira, N; Shinji, S; Nakamura, S; Nihashi, Y; Shimosato, T; Takaya, T.
Myogenetic Oligodeoxynucleotides as Anti-Nucleolin Aptamers Inhibit the Growth of Embryonal Rhabdomyosarcoma Cells.
BIOMEDICINES. 2022 Oct 25;10(11):2691. doi: 10.3390/biomedicines10112691
- Imai, Y;Mori, N; Nihashi, Y; Kumagai, Y; Shibuya, Y; Oshima, J; Sasaki, M; Sasaki, K; Aihara, Y; Sekido, M; Kida, YS.
Therapeutic Potential of Adipose Stem Cell-Derived Conditioned Medium on Scar Contraction Model.
BIOMEDICINES. 2022 Sep 24;10(10):2388. doi: 10.3390/biomedicines10102388
- Ekdahl, KN; Fromell, K; Mannes, M; Grinnemo, KH; Huber-Lang, M;Teramura, Y; Nilsson, B.
Therapeutic regulation of complement activation in extracorporeal circuits and intravascular treatments with special reference to the alternative pathway amplification loop.
IMMUNOL REV. 2022 Oct 18. doi: 10.1111/imr.13148
- Sano, M; Morishita, K; Onizawa, Y; Takagi, T; Sumaru, K.
Rapid and Highly Sensitive Method for Evaluating Surface Coatings against an Enveloped RNA Virus.
ACS APPL BIO MATER. 2022 Oct 14. doi: 10.1021/acsabm.2c00613
- Sugiura, S; Shin, K; Kanamori, T.
Perfusion culture of endothelial cells under shear stress on microporous membrane in a pressure-driven microphysiological system.
J BIOSCI BIOENG. 2022 Oct 14:S1389-1723(22)00258-4. doi: 10.1016/j.jbiosc.2022.09.005
- Tirta, YK; Adachi, S; Perez, CAG; Adhitama, N; Nong, QD; Natsume, T; Kato, Y; Watanabe, H.
CELF1 represses Doublesex1 expression via its 5 UTR in the crustacean Daphnia magna.
PLOS ONE. 2022 Oct 14;17(10):e0275526. doi: 10.1371/journal.pone.0275526
- Tasaki, M; Tateno, H; Sato, T; Narimatsu, H; Saito, K; Nakagawa, Y; Aoki, T; Kamimura, M; Ushiki, T; Takahashi, K; Tomita, Y.
Hyporesponsiveness against donors ABO antigens of renal grafts after ABO-incompatible kidney transplantation.
CLIN EXP NEPHROL. 2022 Oct 8. doi: 10.1007/s10157-022-02280-3
- Hiono, T; Kuno, A.
Glycan Profiling of Viral Glycoproteins with the Lectin Microarray.
METHODS MOL BIOL. 2022;2556:59-68. doi: 10.1007/978-1-0716-2635-1_6
- Shefrin, S; Sari, AN; Kumar, V; Zhang, H; Meidinna, HN; Kaul, SC; Wadhwa, R; Sundar, D.
Comparative computational and experimental analyses of some natural small molecules to restore transcriptional activation function of p53 in cancer cells harbouring wild type and p53(Ser46) mutant.
CURR RES STRUCT BIOL. 2022 Sep 13;4:320-331. doi: 10.1016/j.crstbi.2022.09.002
- Meidinna, HN; Shefrin, S; Sari, AN; Zhang, H; Dhanjal, JK; Kaul, SC; Sundar, D; Wadhwa, R.
Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1.
FRONT CELL DEV BIOL. 2022 Sep 12;10:918970. doi: 10.3389/fcell.2022.918970
- Kosaka, T; Yamaguchi, S; Izuta, S; Yamahira, S; Shibasaki, Y; Tateno, H; Okamoto, A.
Bioorthogonal Photoreactive Surfaces for Single-Cell Analysis of Intercellular Communications.
AM CHEM SOC. 2022 Sep 20. doi: 10.1021/jacs.2c07321
- Sato, R; Suzuki, K; Yasuda, Y; Suenaga, A; Fukui, K.
RNAapt3D: RNA aptamer 3D-structural modeling database.
BIOPHYS J. 2022 Sep 22:S0006-3495(22)00773-1. doi: 10.1016/j.bpj.2022.09.023
- Kawai, S; Hagihara, R; Shin-Ya, K; Katsuyama, Y; Ohnishi, Y.
Bacterial Avenalumic Acid Biosynthesis Includes Substitution of an Aromatic Amino Group for Hydride by Nitrous Acid Dependent Diazotization.
ANGEW CHEM INT ED ENGL. 2022 Sep 17. doi: 10.1002/anie.202211728
- Teranishi, H; Tabata, K; Saeki, M; Umemoto, T; Hatta, T; Otomo, T; Yamamoto, K; Natsume, T; Yoshimori, T; Hamasaki, M.
Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy.
CELL REP. 2022 Sep 13;40(11):111349. doi: 10.1016/j.celrep.2022.111349
- Li, S; Ikeuchi, K; Kato, M; Buschauer, R; Sugiyama, T; Adachi, S; Kusano, H; Natsume, T; Berninghausen, O; Matsuo, Y; Becker, T; Beckmann, R; Inada, T.
Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
MOL CELL. 2022 Sep 15;82(18):3424-3437.e8. doi: 10.1016/j.molcel.2022.08.018
- Miyazaki, K; Itoh, N; Saiki, P; Kuroki, Y.
Supplementation with Eurycoma longifolia Extract Modulates Diurnal Body Temperature Fluctuation and Sleep Rhythm in Mice.
J NUTR SCI VITAMINOL (Tokyo). 2022;68(4):342-347. doi: 10.3177/jnsv.68.342
- Choirunnisa, AR; Arima, K; Abe,Y; Kagaya, K; Kudo, K; Suenaga, H; Hashimoto, J; Fujie, M; Satoh, N; Shin-Ya, K; Matsuda, K; Wakimoto, T.
New azodyrecins identified by a genome mining-directed reactivity-based screening.
BEILSTEIN J ORG CHEM. 2022 Aug 10;18:1017-1025. doi: 10.3762/bjoc.18.102
- Yamasaki, K; Adachi, N; Ngwe Tun, MM; Ikeda, A; Moriya, T; Kawasaki, M; Yamasaki, T; Kubota, T; Nagashima, I; Shimizu, H; Tateno, H; Morita, K.
Core fucose-specific Pholiota squarrosa lectin (PhoSL) as a potent broad-spectrum inhibitor of SARS-CoV-2 infection.
FEBS J. 2022 Aug 25. doi: 10.1111/febs.16599
- Kagiwada, H; Motono, C; Horimoto, K; Fukui, K.
Phosprof: pathway analysis database of drug response based on phosphorylation activity measurements.
DATABASE (Oxford). 2022 Aug 22;2022:baac072. doi: 10.1093/database/baac072
- Higo, J; Kasahara, K; Bekker, GJ; Ma, B; Sakuraba, S; Iida, S; Kamiya, N; Fukuda, I; Kono, H; Fukunishi, Y; Nakamura, H.
Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized flexible molecule.
SCI REP. 2022 Aug 13;12(1):13792. doi: 10.1038/s41598-022-17920-7
- Sugiura, S; Satoh, T; Shin, K; Onuki-Nagasaki, R; Kanamori, T.
Perfusion culture of multi-layered HepG2 hepatocellular carcinoma cells in a pressure-driven microphysiological system.
J BIOSCI BIOENG. 2022 Aug 11:S1389-1723(22)00189-X. doi: 10.1016/j.jbiosc.2022.07.001
- Tomita, T; Kawano, Y; Kassai, M; Onda, H; Nakajima, Y; Miyazaki, K.
Hydroxy-β-sanshool isolated from Zanthoxylum piperitum (Japanese pepper) shortens the period of the circadian clock.
FOOD FUNCT. 2022 Aug 12. doi: 10.1039/d2fo01036d
- Yamagishi, A; Mizusawa, M; Uchida, K; Iijima, M; Kuroda, S; Fukazawa, K; Ishihara, K; Nakamura, C.
Mechanical detection of interactions between proteins related to intermediate filament and transcriptional regulation in living cells.
BIOSENS BIOELECTRON. 2022 Aug 6;216:114603. doi: 10.1016/j.bios.2022.114603
- Katsumi, T; Shams, F; Yanagi, H; Ohnishi, T; Toda, M; Lin, SM; Mawaribuchi, S; Shimizu, N; Ezaz, T; Miura, I.
Highly rapid and diverse sex chromosome evolution in the Odorrana frog species complex.
DEV GROWTH DIFFER. 2022 Jul 26. doi: 10.1111/dgd.12800
- Numakawa, T; Odaka, H.
The Role of Neurotrophin Signaling in Age-Related Cognitive Decline and Cognitive Diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022 Jul 13;23(14):7726. doi: 10.3390/ijms23147726
- Kokubu, R; Ohno, S; Kuratani, H; Takahashi, Y; Manabe, N; Shimizu, H; Chiba, Y; Denda-Nagai, K; Tsuiji, M; Irimura, T; Yamaguchi, Y.
O-Glycan-Dependent Interaction between MUC1 Glycopeptide and MY.1E12 Antibody by NMR, Molecular Dynamics and Docking Simulations.
INT J MOL SCI. 2022 Jul 16;23(14):7855. doi: 10.3390/ijms23147855
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Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity.
PROC NATL ACAD SCI USA. 2022 Aug 16;119(33):e2203437119. doi: 10.1073/pnas.2203437119
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Why is Mortalin a Potential Therapeutic Target for Cancer.
FRONT CELL DEV BIOL. 2022 Jun 29;10:914540. doi: 10.3389/fcell.2022.914540
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Gene Cloning and Functional Analysis of the Luciferase from Luminous Syllids of the Genus Odontosyllis.
METHODS MOL BIOL. 2022;2524:3-15. doi: 10.1007/978-1-0716-2453-1_1
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Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A).
COMMUN BIOL. 2022 Jul 19;5(1):695. doi: 10.1038/s42003-022-03661-w
- Hirata, Y; Oda, AH; Motono, C; Shiro, M; Ohta, K.
Imputation-free reconstructions of three-dimensional chromosome architectures in human diploid single-cells using allele-specified contacts.
SCI REP. 2022 Jul 11;12(1):11757. doi: 10.1038/s41598-022-15038-4
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A medium-chain triglyceride containing ketogenic diet exacerbates cardiomyopathy in a CRISPR/Cas9 gene-edited rat model with Duchenne muscular dystrophy.
SCI REP. 2022 Jul 8;12(1):11580. doi: 10.1038/s41598-022-15934-9
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Repetitive DNA symmetry elements negatively regulate gene expression in embryonic stem cells.
BIOPHYS J. 2022 Jul 8:S0006-3495(22)00557-4. doi: 10.1016/j.bpj.2022.07.011
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Microneedle Array-Assisted, Direct Delivery of Genome-Editing Proteins Into Plant Tissue.
FRONT PLANT SCI. 2022 Jun 24;13:878059. doi: 10.3389/fpls.2022.878059
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Genome-wide CRISPR/Cas9 Screening Identifies KDM2B as a Modifier of Heparan Sulfate-Protein Interactions.
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY. 2022 Volume 34 Issue 199 Pages E63. doi: 10.4052/tigg.2203.6E
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Tendon-Specific Dicer Deficient Mice Exhibit Hypoplastic Tendon Through the Downregulation of Tendon-Related Genes and MicroRNAs.
FRONT CELL DEV BIOL. 2022 Jun 14;10:898428. doi: 10.3389/fcell.2022.898428
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A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme.
J AM CHEM SOC. 2022 Jun 30. doi: 10.1021/jacs.2c05269
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Robotic search for optimal cell culture in regenerative medicine.
ELIFE. 2022 Jun 28;11:e77007. doi: 10.7554/eLife.77007
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Imaging MS Analysis in Catharanthus roseus.
METHODS MOL BIOL. 2022;2505:33-43. doi: 10.1007/978-1-0716-2349-7_2
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Xenopus Dusp6 modulates FGF signaling to precisely pattern pre-placodal ectoderm.
DEVELOPMENTAL BIOLOGY. 2022 May 16. doi: 10.1016/j.ydbio.2022.05.009
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Glycan Profiling by Sequencing to Uncover Multicellular Communication: Launching Glycobiology in Single Cells and Microbiomes.
FRONT CELL DEV BIOL. 2022 May 27;10:919168. doi: 10.3389/fcell.2022.919168
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Glycan expression profile of signet ring cell gastric cancer cells and potential applicability of rBC2LCN-targeted lectin drug conjugate therapy.
GASTRIC CANCER. 2022 Jun 17. doi: 10.1007/s10120-022-01312-x
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Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells.
CELL CHEM BIOL. 2022 Jun 18:S2451-9456(22)00198-2. doi: 10.1016/j.chembiol.2022.05.006
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Identification of ancestral sex chromosomes in the frog Glandirana rugosa bearing XX-XY and ZZ-ZW sex-determining systems.
MOL ECOL. 2022 Jun 12. doi: 10.1111/mec.16551
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The new preparation method for paraffin-embedded samples applying scanning electron microscopy revealed characteristic features in asthma-induced mice.
SCI REP. 2022 May 31;12(1):9046. doi: 10.1038/s41598-022-12666-8
- Adler, A; Manivel, VA; Fromell, K; Teramura, Y; Ekdahl, KN; Nilsson, B.
A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein.
FRONT IMMUNOL. 2022 May 3;13:891994. doi: 10.3389/fimmu.2022.891994
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Autoantibody Landscape Revealed by Wet Protein Array: Sum of Autoantibody Levels Reflects Disease Status.
FRONT IMMUNOL. 2022 May 4;13:893086. doi: 10.3389/fimmu.2022.893086
- Sugisawa, E; Kondo, T; Kumagai, Y; Kato, H; Takayama, Y; Isohashi, K; Shimosegawa, E; Takemura, N; Hayashi, Y; Sasaki, T; Martino, MM; Tominaga, M; Maruyama, K.
Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia.
CELL REP. 2022 Mar 8;38(10):110462. doi: 10.1016/j.celrep.2022.110462
- Kuroki, T; Hatta, T; Natsume, T; Sakai, N; Yagi, A; Kato, K; Nagata, K; Kawaguchi, A.
ARHGAP1 Transported with Influenza Viral Genome Ensures Integrity of Viral Particle Surface through Efficient Budozone Formation.
MBIO. 2022 Apr 27:e0072122. doi: 10.1128/mbio.00721-22
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Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response.
LIFE SCI ALLIANCE. 2022 May 17;5(9):e202101241. doi: 10.26508/lsa.202101241
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Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.
NUCLEIC ACIDS RESEARCH. 2022 May 11. doi: 10.1093/nar/gkac344
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Robotic Biology: Robotics and AI Accelerate Life Science.
CANCER SCIENCE. 113; FEB
- Kuroda, T; Hattori, Y; Kagami, A; Fukuda, E; Tamura, G.
Genetic modification in the body to make friends with cancer cells?! Dreaming of cancer treatment in 100 years.
CANCER SCIENCE. 113 1517-1517; FEB
- Fujimoto, M; Arai, E; Nishiyama, N; Maeshima, A; Fujimoto, H; Kitamura, H; Kuno, A; Yoshida, T; Kanai, Y.
Lectin staining analysis of protein glycosylation in urothelial carcinomas.
CANCER SCIENCE. 113 378-378; FEB
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Alteration of protein glycosylation in renal carcinogenesis.
CANCER SCIENCE. 113 1284-1284; FEB
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Discovery of prescopranone, a key intermediate in scopranone biosynthesis.
JOURNAL OF ANTIBIOTICS. 2022 Apr 20. doi: 10.1038/s41429-022-00521-x
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Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1.
J VIROL. 2022 Apr 27:e0030622. doi: 10.1128/jvi.00306-22
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CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner.
RNA BIOL. 2022;19(1):703-718. doi: 10.1080/15476286.2022.2071026
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Stable G-quadruplex DNA structures promote replication-dependent genome instability.
J BIOL CHEM. 2022 Apr 18:101947. doi: 10.1016/j.jbc.2022.101947
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Prognostic significance of NY-ESO-1 antigen and PIGR expression in esophageal tumors of CHP-NY-ESO-1-vaccinated patients as adjuvant therapy.
CANCER IMMUNOL IMMUNOTHER. 2022 Apr 16. doi: 10.1007/s00262-022-03194-5
- Odaka, H; Hiemori, K; Shimoda, A; Akiyoshi, K; Tateno, H.
CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma.
BMC GASTROENTEROLOGY. 2022 Mar 28;22(1):153. doi: 10.1186/s12876-022-02228-7
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The therapeutic capacity of bone marrow MSC-derived extracellular vesicles in Achilles tendon healing is passage-dependent and indicated by specific glycans.
FEBS LETTERS. 2022 Apr;596(8):1047-1058. doi: 10.1002/1873-3468.14333
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A Novel Method of CD31-Combined ABO Carbohydrate Antigen Microarray Predicts Acute Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation.
TRANSPL INT. 2022 Mar 23;35:10248. doi: 10.3389/ti.2022.10248
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Quantitative evaluation of glycan-binding specificity of recombinant Concanavalin A produced in lettuce (Lactuca sativa).
BIOTECHNOL BIOENG. 2022 Apr 8. doi: 10.1002/bit.28099
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Photoinduced cytotoxicity of photochromic symmetric diarylethene derivatives: the relation of structure and cytotoxicity.
ORGANIC & BIOMOLECULAR CHEMISTRY. 2022 Apr 13;20(15):3211-3217. doi: 10.1039/d2ob00224h
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Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts.
CANCERS. 2022 Mar 8;14(6):1375. doi: 10.3390/cancers14061375
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Entamoeba histolytica EHD1 Is Involved in Mitosome-Endosome Contact.
MBIO. 2022 Apr 11:e0384921. doi: 10.1128/mbio.03849-21
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Systematic Investigation of Lanthanoid Transition Heavy Metal Acetates as Electron Staining Reagents for Protein Molecules in Biological Transmission Electron Microscopy.
MICROSC MICROANAL. 2022 Apr 1:1-10. doi: 10.1017/S1431927622000411
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Discovery by metagenomics of a functional tandem repeat sequence that controls gene expression in bacteria.
FEMS MICROBIOL ECOL. 2022 Mar 28:fiac037. doi: 10.1093/femsec/fiac037
2021年
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Time-of-day effects of consumption of fish oil-enriched sausages on serum lipid parameters and fatty acid composition in normolipidemic adults: A randomized, double-blind, placebo-controlled, and parallel-group pilot study.
Nutrition. 2021;90:111247. doi: 10.1016/j.nut.2021.111247
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Synthesis of Crosslinked 2-OMe RNA Duplexes Using 2-Amino-6-Vinylpurine and Their Application for Effective Inhibition of miRNA Function.
CURR PROTOC. Mar;2(3):e386. doi: 10.1002/cpz1.386
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Characterization of phalloidin-negative nuclear actin filaments in U2OS cells expressing cytoplasmic actin-EGFP.
GENES TO CELLS. 2022 Feb 23. doi: 10.1111/gtc.12930
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Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method.
J EXTRACELL VESICLES. 2022 Mar;11(3):e12205. doi: 10.1002/jev2.12205
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Role of the TOM Complex in Protein Import into Mitochondria: Structural Views.
ANNU REV BIOCHEM. 2022 Feb 14. doi: 10.1146/annurev-biochem-032620-104527
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An organ-derived extracellular matrix triggers in situ kidney regeneration in a preclinical model.
NPJ REGEN MED. 2022 Feb 28;7(1):18. doi: 10.1038/s41536-022-00213-y
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Multiple protonation states in ligand-free SARS-CoV-2 main protease revealed by large-scale quantum molecular dynamics simulations.
CHEM PHYS LETT. 2022 Feb 22;794:139489. doi: 10.1016/j.cplett.2022.139489
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Phosphatidylserine Exposed Lipid Bilayer Models for Understanding Cancer Cell Selectivity of Natural Compounds: A Molecular Dynamics Simulation Study.
MEMBRANES 12 (1);doi: 10.3390/membranes12010064 JAN
- Malik, V; Radhakrishnan, N; Kaul, SC; Wadhwa, R; Sundar, D.
Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A and Withanone.
BIOMOLECULES 12 (2);doi: 10.3390/biom12020212 FEB
- Nagata, R; Suemune, H; Kobayashi, M; Shinada, T; Shin-Ya, K; Nishiyama, M; Hino, T; Sato, Y; Kuzuyama, T; Nagano, S.
Structural Basis for the Prenylation Reaction of Carbazole-Containing Natural Products Catalyzed by Squalene Synthase-like Enzymes.
ANGEW CHEM INT ED ENGL. 2022 Mar 2. doi: 10.1002/anie.202117430
- Mitani, Y; Yasuno, R; Kihira, K; Chung, KM; Mitsuda, N; Kanie, S; Tomioka, A; Kaji, H; Ohmiya, Y.
Host-Dependent Producibility of Recombinant Cypridina noctiluca Luciferase With Glycosylation Defects.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 10;doi: 10.3389/fbioe.2022.774786 FEB 7
- Odaka, H; Ozaki, H; Tateno, H.
scGR-seq: Integrated analysis of glycan and RNA in single cells.
STAR PROTOC. 2022 Feb 18;3(1):101179. doi: 10.1016/j.xpro.2022.101179. eCollection
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A Low Dose Combination of Withaferin A and Caffeic Acid Phenethyl Ester Possesses Anti-Metastatic Potential In Vitro: Molecular Targets and Mechanisms.
CANCERS (Basel). 2022 Feb 3;14(3):787. doi: 10.3390/cancers14030787
- Irumagawa, S; Hiemori, K; Saito, S; Tateno, H; Arai, R.
Self-Assembling Lectin Nano-Block Oligomers Enhance Binding Avidity to Glycans.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (2);doi: 10.3390/ijms23020676 JAN
- Suzuki, R; Nakamura, Y; Koiwai, R; Fuseya, S; Murakami, Y; Hagiwara, K; Sato, T; Takahashi, S; Kudo, T.
Global Loss of Core 1-Derived O-Glycans in Mice Leads to High Mortality Due to Acute Kidney Failure and Gastric Ulcers.
INT J MOL SCI. 2022 Jan 24;23(3):1273. doi: 10.3390/ijms23031273
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Anti-Inflammatory Effects of Heliangin from Jerusalem Artichoke (Helianthus tuberosus) Leaves Might Prevent Atherosclerosis.
BIOMOLECULES 12 (1); doi:10.3390/biom12010091 JAN
- Penedo, M; Miyazawa, K; Okano, N; Furusho, H; Ichikawa, T; Alam, MS; Miyata, K; Nakamura, C; Fukuma, T.
Visualizing intracellular nanostructures of living cells by nanoendoscopy-AFM.
SCI ADV. 2021 Dec 24;7(52):eabj4990. doi: 10.1126/sciadv.abj4990. Epub 2021 Dec 22
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Sensitive New Assay System for Serum Wisteria floribunda Agglutinin-Reactive Ceruloplasmin That Distinguishes Ovarian Clear Cell Carcinoma from Endometrioma.
ANALYTICAL CHEMISTRY; doi:10.1021/acs.analchem.1c04302
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Draft Genome Sequence of Bryobacteraceae Strain F-183.
MICROBIOL RESOUR ANNOUNC. 2022 Jan 13:e0045321. doi: 10.1128/mra.00453-21
- Malik, V; Kumar, V; Kaul, SC; Wadhwa, R; Sundar, D.
Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl ester as ATP-competitive inhibitors of BRAF: A bioinformatics study.
CURR RES STRUCT BIOL. 2021 Nov 18;3:301-311. doi: 10.1016/j.crstbi.2021.11.004
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Enhancement of intercellular interaction between iPSC-derived neural progenitor cells and activated endothelial cells using cell surface modification with functional oligopeptides.
BIOMATER SCI. 2022 Jan 11. doi: 10.1039/d1bm01503f
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Molecular Insights into the Antistress Potentials of Brazilian Green Propolis Extract and Its Constituent Artepillin C.
MOLECULES. 2021 Dec 23;27(1):80. doi: 10.3390/molecules27010080
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Recent advances in research on biointerfaces: From cell surfaces to artificial interfaces.
J BIOSCI BIOENG. 2022 Jan 5:S1389-1723(21)00331-5. doi: 10.1016/j.jbiosc.2021.12.004
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Calcification in Werner syndrome associated with lymphatic vessels aging.
AGING (Albany NY). 2021 Dec 27;13(undefined). doi: 10.18632/aging.203789
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A New ICEclc Subfamily Integrative and Conjugative Element Responsible for Horizontal Transfer of Biphenyl and Salicylic Acid Catabolic Pathway in the PCB-Degrading Strain Pseudomonas stutzeri KF716.
MICROORGANISMS. 2021 Nov 29;9(12):2462. doi: 10.3390/microorganisms9122462
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Characterization of an extracellular α-xylosidase involved in xyloglucan degradation in Aspergillus oryzae.
APPL MICROBIOL BIOTECHNOL. 2021 Dec 31. doi: 10.1007/s00253-021-11744-7
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Tissue Glycome Mapping: Lectin Microarray-Based Differential Glycomic Analysis of Formalin-Fixed Paraffin-Embedded Tissue Sections.
METHODS MOL BIOL. 2022;2460:161-180. doi: 10.1007/978-1-0716-2148-6_10
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Caffeic acid phenethyl ester (CAPE) confers wild type p53 function in p53(Y220C) mutant: bioinformatics and experimental evidence.
DISCOVER ONCOLOGY 12 (1);doi: 10.1007/s12672-021-00461-2 DEC 20
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Evaluation of Glycan-Binding Specificity by Glycoconjugate Microarray with an Evanescent-Field Fluorescence Detection System.
METHODS MOL BIOL. 2022;2460:25-32. doi: 10.1007/978-1-0716-2148-6_2
- Higashi, H; Yagi, H; Kuroda, K; Tajima, K; Kojima, H; Nishi, K; Morisaku, T; Hirukawa, K; Fukuda, K; Matsubara, K; Kitago, M; Shinoda, M; Obara, H; Adachi, S; Nishimura, K; Natsume, T; Tomi, M; Soto-Gutierrez, A; Kitagawa, Y.
Transplantation of Bioengineered Liver Capable of Extended Function in a Preclinical Liver Failure Model.
AM J TRANSPLANT. 2021 Dec 21. doi: 10.1111/ajt.16928
- Aizawa, S; Nishimura, K; Mondejar, GS; Kumar, A; Bui, PL; Tran, YTH; Kuno, A; Muratani, M; Kobayashi, S; Nabekura, T; Shibuya, A; Sugihara, E; Sato, TA; Fukuda, A; Hayashi, Y; Hisatake, K.
Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming.
STEM CELL REPORTS. 2021 Nov 29:S2213-6711(21)00589-0. doi10.1016/j.stemcr.2021.11.008
- Zhang, M; Kiyono, T; Aoki, K; Goshima, N; Kobayashi, S; Hiranuma, K; Shiraishi, K; Saya, H; Nakahara, T.
Development of an in vitro carcinogenesis model of HPV induced cervical adenocarcinoma.
CANCER SCI. 2021 Dec 21. doi: 10.1111/cas.15246
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DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis.
J EXP MED. 2021 Dec 6;218(12):e20210435. doi: 10.1084/jem.20210435. Epub 2021 Nov
- Shimoda, A; Miura, R; Tateno, H; Seo, N; Shiku, H; Sawada, S; Sasaki, Y; Akiyoshi, K.
Assessment of Surface Glycan Diversity on Extracellular Vesicles by Lectin Microarray and Glycoengineering Strategies for Drug Delivery Applications.
SMALL METHODS; doi: 10.1002/smtd.202100785
- Tulin, EKC; Nakazawa, C; Nakamura, T; Saito, S; Ohzono, N; Hiemori, K; Nakakita, SI; Tateno, H; Tonozuka, T; Nishikawa, A.
Glycan detecting tools developed from the Clostridium botulinum whole hemagglutinin complex.
SCI REP. 2021 Nov 9;11(1):21973. doi: 10.1038/s41598-021-01501-1
- Kaigawa, H; Tateno, H; Arai, R.
Self-Assembling Functional Complexes of Protein Nanobuilding Blocks with a Trimeric Lectin.
PROTEIN SCIENCE 30 158-159; OCT
- Irumagawa, S; Tateno, H; Arai, R.
Self-Assembling Lectin Nano-Building Blocks Enhance Avidity to Glycans through Polyvalent Effect.
PROTEIN SCIENCE 30 173-174; OCT
- Takayanagi, S; Watanabe, K; Maruyama, T; Ogawa, M; Morishita, K; Soga, M; Hatta, T; Natsume, T; Hirano, T; Kagechika, H; Hattori, K; Naguro, I; Ichijo, H.
ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes.
SCI REP. 2021 Nov 10;11(1):22009. doi: 10.1038/s41598-021-01123-7
- Shigi, N.
Biosynthesis and Degradation of Sulfur Modifications in tRNAs.
INT J MOL SCI. 2021 Nov 3;22(21):11937. doi: 10.3390/ijms222111937
- Hurd, MD; Goel, I; Sakai, Y; Teramura, Y.
Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine.
REGENERATIVE THERAPY 18 408-417; doi:10.1016/j.reth.2021.09.009 DEC
- Queliconi BB, Kojima W, Kimura M, Imai K, Udagawa C, Motono C, Hirokawa T, Tashiro S, Caaveiro JMM, Tsumoto K, Yamano K, Tanaka K, Matsuda N.
Unfolding is the driving force for mitochondrial import and degradation of Parkinsons disease-related protein DJ-1.
J CELL SCI. 2021 Oct 22:jcs.258653. doi: 10.1242/jcs.258653
- Wang, J; Zhang, H; Kaul, A; Li, K; Priyandoko, D; Kaul, SC; Wadhwa, R.
Effect of Ashwagandha Withanolides on Muscle Cell Differentiation.
BIOMOLECULES. 2021 Oct 4;11(10):1454. doi: 10.3390/biom11101454
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Computational and in vitro experimental analyses of the anti-COVID-19 potential of Mortaparib and MortaparibPlus.
BIOSCI REP. 2021 Oct 29;41(10):BSR20212156. doi: 10.1042/BSR20212156
- Adler, A; Inoue, Y; Ekdahl, KN; Baba, T; Ishihara, K; Nilsson, B; Teramura, Y.
Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins.
J MATER CHEM B. 2021 Oct 7. doi: 10.1039/d1tb01485d
- Sano, M; Morishita, K; Oikawa, S; Akimoto, T; Sumaru, K; Kato, Y.
Live-cell imaging of microRNA expression with post-transcriptional feedback control.
MOL THER NUCLEIC ACIDS. 2021 Aug 26;26:547-556. doi: 10.1016/j.omtn.2021.08.018
- Tsutsumi, H; Moriwaki, Y; Terada, T; Shimizu, K; Shin-Ya, K; Katsuyama, Y; Ohnishi, Y.
Structural and Molecular Basis of the Catalytic Mechanism of Geranyl Pyrophosphate C-6 Methyltransferase: Creation of an Unprecedented Farnesyl Pyrophosphate C-6 Methyltransferase.
ANGEW CHEM INT ED ENGL. 2021 Oct 9. doi: 10.1002/anie.202111217
- Nakatani, E; Yamazaki, W; Sugiura, S; Kanamori, T; Ohnuma, K.
Modeling of differentiation pattern formation in human induced pluripotent stem cells mediated by BMP4 and its inhibitor noggin secreted from cells.
BIOCHEMICAL ENGINEERING JOURNAL 176; doi: 10.1016/j.bej.2021.108159 DEC
- Hoshi, K; Ito, H; Abe, E; Fuwa, TJ; Kanno, M; Murakami, Y; Abe, M; Murakami, T, Yoshihara, A, Ugawa, Y, Saito, T, Saido, TC, Matsumoto, K, Yamaguchi, Y, Furukawa, K, Arai, H, Kanai, M, Miyajima, M, Arai, H, Ogawa, N, Akatsu, H, Hashizume, Y, Tateno, H, Honda, T, Hashimoto, Y.
Transferrin Biosynthesized in the Brain Is a Novel Biomarker for Alzheimers Disease.
METABOLITES. 2021 Sep 10;11(9):616. doi: 10.3390/metabo11090616
- Angata, K; Wagatsuma, T; Togayachi, A; Sato, T; Sogabe, M; Tajiri, K; Ozawa, T; Nagashima, I; Shimizu, H; Iijima, S; Korenaga, M; Kuno, A; Kaji, H; Mizokami, M; Narimatsu, H.
O-glycosylated HBsAg peptide can induce specific antibody neutralizing HBV infection.
BIOCHIM BIOPHYS ACTA GEN SUBJ. 2021 Sep 25:130020. doi: 10.1016/j.bbagen.2021.130020
- Fujikura, Y; Sugihara, H; Hatakeyama, M; Oishi, K; Yamanouchi, K.
Ketogenic diet with medium-chain triglycerides restores skeletal muscle function and pathology in a rat model of Duchenne muscular dystrophy.
FASEB J. 2021 Sep;35(9):e21861. doi: 10.1096/fj.202100629R
- Bhargava, P; Mahanta, D; Kaul, A; Ishida, Y; Terao, K; Wadhwa, R; Kaul, SC.
Experimental Evidence for Therapeutic Potentials of Propolis.
NUTRIENTS. 2021 Jul 24;13(8):2528. doi: 10.3390/nu13082528
- Kumar, A; Konar, A; Garg, S; Kaul, SC; Wadhwa, R.
Experimental evidence and mechanism of action of some popular neuro-nutraceutical herbs.
NEUROCHEMISTRY INTERNATIONAL 149; doi: 10.1016/j.neuint.2021.105124
- Takeuchi, K; Kofuku, Y; Imai, S; Ueda, T; Tokunaga, Y; Toyama, Y; Shiraishi, Y; Shimada, I.
Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR.
MEMBRANES (Basel). 2021 Aug 9;11(8):604. doi: 10.3390/membranes11080604
- Yoko-O, T; Komatsuzaki, A; Yoshihara, E; Zhao, S; Umemura, M; Gao, XD; Chiba, Y.
Regulation of alcohol oxidase gene expression in methylotrophic yeast Ogataea minuta.
J BIOSCI BIOENG. 2021 Aug 27:S1389-1723(21)00204-8. doi: 10.1016/j.jbiosc.2021.08.001
- Kaul, Z; Cheung, CTY; Bhargava, P; Sari, AN ; Yu, Y; He, HF; Bid, H; Henson, JD; Groden, J; Reddel, RR; Kaul, SC; Wadhwa, R.
Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells.
SCI REP. 2021 Aug 23;11(1):17052. doi: 10.1038/s41598-021-96096-y
- Isaka, E; Sugiura, T; Hashimoto, K; Kikuta, K; Anazawa, U; Nomura, T; Kameyama, A.
Characterization of tumor-associated MUC1 and its glycans expressed in mucoepidermoid carcinoma.
ONCOLOGY LETTERS 22 (4);doi: 10.3892/ol.2021.12963 OCT
- Minoshima, F; Ozaki, H; Odaka, H; Tateno, H.
Integrated analysis of glycan and RNA in single cells.
ISCIENCE. 2021 Jul 17;24(8):102882. doi: 10.1016/j.isci.2021.102882. eCollection
- Funakoshi, Y; Ohji, G; Yakushijin, K; Ebisawa, K; Arakawa, Y; Saegusa, J; Matsumoto, H; Imanishi, T; Fukuda, E; Matsutani, T; Mori, Y; Iwata, K; Minami, H.
Massive surge of mRNA expression of clonal B-cell receptor in patients with COVID-19.
HELIYON. 2021 Aug;7(8):e07748. doi: 10.1016/j.heliyon.2021.e07748. Epub 2021 Aug 10
- Watanabe, T; Takeda, K; Hiemori, K; Minamisawa, T; Tateno, H.
A glycosaminoglycan microarray identifies the binding of SARS-CoV-2 spike protein to chondroitin sulfate E.
FEBS LETT. 2021 Aug 10. doi: 10.1002/1873-3468.14173
- Perez, CAG; Adachi, S; Nong, QD; Adhitama, N; Matsuura, T; Natsume, T; Wada, T; Kato, Y; Watanabe, H.
Sense-overlapping lncRNA as a decoy of translational repressor protein for dimorphic gene expression.
PLOS GENET. 2021 Jul 28;17(7):e1009683. doi: 10.1371/journal.pgen.1009683
- Kimura, M; Imai, K; Morinaka, Y; Hosono-Sakuma, Y; Horton, P; Imamoto, N.
Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding.
SCI REP. 2021 Aug 2;11(1):15649. doi: 10.1038/s41598-021-94948-1
- Sato, Y; Asawa, K; Huang, T; Noiri, M; Nakamura, N; Ekdahl, KN; Nilsson, B; Ishihara, K; Teramura, Y.
Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids.
LANGMUIR. 2021 Aug 3. doi: 10.1021/acs.langmuir.1c01072
- Suenaga, H; Kagaya, N; Kawada, M; Tatsuda, D; Sato, T; Shin-Ya, K.
Phenotypic screening system using three-dimensional (3D) culture models for natural product screening.
J ANTIBIOT (Tokyo). 2021 Jul 29. doi: 10.1038/s41429-021-00457-8
- Konno, S; Kobayashi, K; Senda, M; Funai, Y; Seki, Y; Tamai, I; Schäkel, L; Sakata, K; Pillaiyar, T; Taguchi, A; Taniguchi, A; Gütschow, M; Müller, CE; Takeuchi, K; Hirohama, M; Kawaguch,i A; Kojima, M; Senda, T; Shirasaka, Y; Kamitani, W; Hayashi, Y.
3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.
J MED CHEM. 2021 Jul 27. doi: 10.1021/acs.jmedchem.1c00665
- Motono, C; Yanagida, S; Sato, M; Hirokawa, T.
MDContactCom: a tool to identify differences of protein molecular dynamics from two MD simulation trajectories in terms of interresidue contacts.
BIOINFORMATICS. 2021 Jul 21:btab538. doi: 10.1093/bioinformatics/btab538
- Adler, A; Inoue, Y; Sato, Y; Ishihara, K; Ekdahl, KN; Nilsson, B; Teramura, Y.
Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions.
BIOMATER SCI. 2021 Jul 20. doi: 10.1039/d1bm00570g
- Haramoto, Y.
First person - Yoshikazu Haramoto.
BIOLOGY OPEN 10 (4);doi: 10.1242/bio.058759 APR
- Seimiya, H; Nagasawa, K; Shin-Ya, K.
Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics.
J ANTIBIOT (Tokyo). 2021 Jul 20. doi: 10.1038/s41429-021-00454-x
- Mostafa, Abdelhady A; Hirano, Y; Onizuka, K; Okamura, H; Komatsu, Y; Nagatsugi, F.
Synthesis of Crosslinked 2-OMe RNA Duplexes and Their Application for Effective Inhibition of miRNA Function.
BIOORG MED CHEM LETT. 2021 Jul 8:128257. doi: 10.1016/j.bmcl.2021.128257
- Iida, S; Fukunishi, Y.
Asymmetric dynamics of dimeric SARS-CoV-2 and SARS-CoV main proteases in an apo form: Molecular dynamics study on fluctuations of active site, catalytic dyad, and hydration water.
BBA ADV. 2021;1:100016. doi: 10.1016/j.bbadva.2021.100016. Epub 2021 Jun 20
- Ninomiya, K; Iwakiri, J; Aly, MK; Sakaguchi, Y; Adachi, S; Natsume, T; Terai, G; Asai, K; Suzuki, T; Hirose, T.
m(6) A modification of HSATIII lncRNAs regulates temperature-dependent splicing.
EMBO J. 2021 Jun 29:e107976. doi: 10.15252/embj.2021107976
- Elwakeel, A; Sari, AN; Dhanjal, JK; Meidinna, HN; Sundar, D; Kaul, SC; Wadhwa, R.
Mutant p53(L194F) Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to Mortaparib(Plus), a Multimodal Small Molecule Inhibitor.
CANCERS (Basel). 2021 Jun 18;13(12):3043. doi: 10.3390/cancers13123043
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N-glycan structures of Wisteria floribunda agglutinin-positive Mac2 binding protein in the serum of patients with liver fibrosis.
GLYCOBIOLOGY. 2021 Jun 29:cwab060. doi: 10.1093/glycob/cwab060
- Hashimoto, M; Murai, Y; Morita, K; Kikukawa, T; Takagi, T; Takahashi, H; Yokoyama, Y; Amii, H; Sonoyama, M.
Comparison of functionality and structural stability of bacteriorhodopsin reconstituted in partially fluorinated dimyristoylphosphatidylcholine liposomes with different perfluoroalkyl chain lengths.
BIOCHIM BIOPHYS ACTA BIOMEMBR. 2021 Jun 25;1863(10):183686. doi: 10.1016/j.bbamem.2021.183686
- Ogita, Y; Tamura, K; Mawaribuchi, S; Takamatsu, N; Ito, M.
Independent pseudogenizations and losses of sox15 during amniote diversification following asymmetric ohnolog evolution.
BMC ECOL EVOL. 2021 Jun 30;21(1):134. doi: 10.1186/s12862-021-01864-z
- Yamagishi, A; Ito, F; Nakamura, C.
Study on Cancer Cell Invasiveness via Application of Mechanical Force to Induce Chloride Ion Efflux.
ANAL CHEM. 2021 Jun 21. doi: 10.1021/acs.analchem.1c01589
- Tomita, T; Wadhwa, R; Kaul, SC; Kurita, R; Kojima, N; Onishi, Y.
Withanolide Derivative 2,3-Dihydro-3β-methoxy Withaferin-A Modulates the Circadian Clock via Interaction with RAR-Related Orphan Receptor α (RORa.
J NAT PROD. 2021 Jun 21. doi: 10.1021/acs.jnatprod.0c01276
- Kagiwada, H; Kiboku, T; Matsuo, H; Kitazawa, M; Fukui, K; Horimoto, K.
Assessing the activation/inhibition of tyrosine kinase-related pathways with a newly developed platform.
PROTEOMICS. 2021 Jun 21:e2000251. doi: 10.1002/pmic.202000251
- Dhanjal, JK; Kumar, V; Garg, S; Subramani, C; Agarwal, S; Wang, J; Zhang, H; Kaul, A; Kalra, RS; Kaul, SC; Vrati, S; Sundar, D; Wadhwa, R
Molecular mechanism of anti-SARS-CoV2 activity of Ashwagandha-derived withanolides
Int J Biol Macromol. 2021 Jun 9:S0141-8130(21)01215-0. doi: 10.1016/j.ijbiomac.2021.06.015
- Furuta, T; Oda, T; Kiyoi, K; Ozawa, Y; Kimura, S; Kurimori, K; Miyazaki, Y; Yu, Y; Furuya, K; Akashi, Y; Shimomura, O; Tateno, H
Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells
Cancer Sci. 2021 Jun 11. doi: 10.1111/cas.15023
- Okumura, S; Hirano, Y; Komatsu, Y.
Stable duplex-linked antisense targeting miR-148a inhibits breast cancer cell proliferation.
SCI REP. 2021 Jun 1;11(1):11467. doi: 10.1038/s41598-021-90972-3
- Suzuki, T; Katayama, Y; Komatsu, Y; Kamiya, H.
Similar frequency and signature of untargeted substitutions induced by abasic site analog under reduced human APE1 conditions.
J TOXICOL SCI. 2021;46(6):283-288. doi: 10.2131/jts.46.283
- Numakawa, T; Odaka, H.
Brain-Derived Neurotrophic Factor Signaling in the Pathophysiology of Alzheimers Disease: Beneficial Effects of Flavonoids for Neuroprotection.
INT J MOL SCI. 2021 May 27;22(11):5719. doi: 10.3390/ijms22115719
- Yoneda, Y; Yamamoto, K; Makino, A; Tanaka, Y; Meng, XY; Hashimoto, J; Shin-Ya, K; Satoh, N; Fujie, M; Toyama, T; Mori, K; Ike, M; Morikawa, M; Kamagata, Y; Tamaki, H
Novel Plant-Associated Acidobacteria Promotes Growth of Common Floating Aquatic Plants, Duckweeds
Microorganisms. 2021 May 24;9(6):1133. doi: 10.3390/microorganisms9061133
- Mogi, K; Kimura, H; Kondo, Y; Inoue, T; Adachi, S; Natsume, T.
Automatic radioisotope manipulation for small amount of nuclear medicine using an EWOD device with a dimple structure.
R SOC OPEN SCI. 2021 May 26;8(5):201809. doi: 10.1098/rsos.201809
- Nishimura, T; Kawahara, T; Kagaya, N; Ogura, Y; Takikawa, H; Suenaga, H; Adachi, M; Hirokawa, T; Doi, T; Shin-Ya, K.
JBIR-155, a Specific Class D β-Lactamase Inhibitor of Microbial Origin.
ORG LETT. 2021 May 24. doi: 10.1021/acs.orglett.1c01352
- Kudo, K; Nishimura, T; Kozone, I; Hashimoto, J; Kagaya, N; Suenaga, H; Ikeda, H; Shin-Ya, K.
Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase.
SCI REP. 2021 May 11;11(1):9944. doi: 10.1038/s41598-021-88583-z
- Amemiya, T; Horimoto, K; Fukui, K.
Application of multiple omics and network projection analyses to drug repositioning for pathogenic mosquito-borne viruses.
SCI REP. 2021 May 12;11(1):10136. doi: 10.1038/s41598-021-89171-x
- Sakata-Matsuzawa, M; Denda-Nagai, K; Fujihira, H; Noji, M; Ishii-Schrade, KB; Matsuda, A; Kuno, A; Okazaki, M; Nakai, K; Horimoto, Y; Saito, M; Irimura, T
Glycans unique to the relapse-prone subset within triple-negative breast cancer as revealed by lectin array-based analysis of surgical specimens
PLoS One. 2021 May 11;16(5):e0250747. doi: 10.1371/journal.pone.0250747. eCollection
- Baba, T; Tanimura, S; Yamaguchi, A; Horikawa, K; Yokozeki, M; Hachiya, S; Iemura, SI; Natsume, T; Matsuda, N; Takeda, K.
Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteinsduring mitophagy.
BIOCHIM BIOPHYS ACTA MOL CELL RES. 2021 Apr 16:119045. doi: 10.1016/j.bbamcr.2021.119045
- Tokunaga, Y; Tanaka, M; Iida, H; Kinoshita, M; Tojima, Y; Takeuchi, K; Imashimizu, M.
Nonthermal excitation effects mediated by subterahertz radiation on hydrogen exchange in ubiquitin
BIOPHYS J. 2021 Apr 21:S0006-3495(21)00329-5. doi: 10.1016/j.bpj.2021.04.013
- Akagi, Y; Mori, N; Kawamura, T; Takayama, Y; Kida, YS.
Non-invasive cell classification using the Paint Raman Express Spectroscopy System (PRESS)
SCI REP. 2021 Apr 23;11(1):8818. doi: 10.1038/s41598-021-88056-3
- Liu, C; Hashimoto, J; Kudo, K; Shin-Ya, K; Kakeya, H.
An Atypical Arginine Dihydrolase Involved in the Biosynthesis of Cyclic Hexapeptide Longicatenamides.
CHEM ASIAN J. 2021 Apr 22. doi: 10.1002/asia.202100181
- Kaneko, S; Mitsuyama, T; Shiraishi, K; Ikawa, N; Shozu, K; Dozen, A; Machino, H; Asada, K; Komatsu, M; Kukita, A; Sone, K; Yoshida, H; Motoi, N; Hayami, S; Yoneoka, Y; Kato, T; Kohno, T; Natsume, T; Keudell, GV; Saloura, V; Yamaue, H; Hamamoto, R
Genome-Wide Chromatin Analysis of FFPE Tissues Using a Dual-Arm Robot with Clinical Potential
Cancers (Basel). 2021 Apr 28;13(9):2126. doi: 10.3390/cancers13092126
- Li, X; Wang, J; Zhang, H; Xiao, L; Lei, Z; Kaul, SC; Wadhwa, R; Zhang, Z.
Low Dose of Fluoride in the Culture Medium of Cordyceps militaris Promotes Its Growth and Enhances Bioactives with Antioxidant and Anticancer Properties.
J FUNGI (Basel). 2021 Apr 28;7(5):342. doi: 10.3390/jof7050342
- Kohrogi, K; Hino, S; Sakamoto, A; Anan, K; Takase, R; Araki, H; Hino, Y; Araki, K; Sato, T; Nakamura, K; Nakao, M
LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBP
Blood Adv. 2021 May 11;5(9):2305-2318. doi: 10.1182/bloodadvances.2020003521
- Okubo, S; Ena, E; Okuda, A; Kozone, I; Hashimoto, J; Nishitsuji, Y; Fujie, M; Satoh, N; Ikeda, H; Shin-Ya, K.
Identification of functional cytochrome P450 and ferredoxin from Streptomyces sp. EAS-AB2608 by transcriptional analysis and their heterologous expression.
APPL MICROBIOL BIOTECHNOL. 2021 May 4. doi: 10.1007/s00253-021-11304-z
- Haramoto, Y; Sakata, M; Kobayashi, S.
Visualization of X chromosome reactivation in mouse primordial germ cells in vivo.
BIOL OPEN. 2021 Apr 15;10(4):bio058602. doi: 10.1242/bio.058602. Epub 2021 Apr 29
- Mori, N; Kida, YS.
Applicability of Artificial Vascularized Liver Tissue to Proteomic Analysis.
MICROMACHINES (Basel). 2021 Apr 11;12(4):418. doi: 10.3390/mi12040418
- Moritsugu, K; Takeuchi, K; Kamiya, N; Higo, J; Yasumatsu, I; Fukunishi, Y; Fukuda, I.
Flexibility and Cell Permeability of Cyclic Ras-Inhibitor Peptides Revealed by the Coupled Nosé-Hoover Equation.
J CHEM INF MODEL. 2021 Apr 9. doi: 10.1021/acs.jcim.0c01427
- Penedo, M; Shirokawa, T; Alam, MS; Miyazawa, K; Ichikawa, T; Okano, N; Furusho, H; Nakamura, C; Fukuma, T.
Cell penetration efficiency analysis of different atomic force microscopy nanoneedles into living cells.
SCI REP. 2021 Apr 8;11(1):7756. doi: 10.1038/s41598-021-87319-3
- Ohashi, H; Watashi, K; Saso, W; Shionoya, K; Iwanami, S; Hirokawa, T; Shirai, T; Kanaya, S; Ito, Y; Kim, KS; Nomura, T; Suzuki, T; Nishioka, K; Ando, S; Ejima, K; Koizumi, Y; Tanaka, T; Aoki, S; Kuramochi, K; Suzuki, T; Hashiguchi, T; Maenaka, K; Matano, T; Muramatsu, M; Saijo, M; Aihara, K; Iwami, S; Takeda, M; McKeating, JA; Wakita, T
Potential anti-COVID-19 agents, Cepharanthine and Nelfinavir, and their usage for combination treatment.
ISCIENCE. 2021 Mar 26:102367. doi: 10.1016/j.isci.2021.102367
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Rapid Prototyping of a Nanoparticle Concentrator Using a Hydrogel Molding Method.
POLYMERS (Basel). 2021 Mar 29;13(7):1069. doi: 10.3390/polym13071069
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Molecular Dynamics Simulation Study on Allosteric Regulation of CD44-Hyaluronan Binding as a Force Sensing Mechanism.
ACS OMEGA. 2021 Mar 16;6(12):8045-8055. doi: 10.1021/acsomega.0c05502. eCollection
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COVID19-inhibitory activity of withanolides involves targeting of the host cell surface receptor ACE2: insights from computational and biochemical assays.
J BIOMOL STRUCT DYN. 2021 Apr 2:1-14. doi: 10.1080/07391102.2021.1902858
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Structural and functional analyses of the tridomain-nonribosomal peptide synthetase FmoA3 for 4-methyloxazoline ring formation
Angew Chem Int Ed Engl. 2021 Mar 29. doi: 10.1002/anie.202102760
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RNA. 2021 Mar 23:rna.078287.120. doi: 10.1261/rna.078287.120
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BIOCHEM BIOPHYS RES COMMUN. 2021 Mar 25;554:13-18. doi: 10.1016/j.bbrc.2021.03.078
2020年
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Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo
J Pestic Sci. 2021 Feb 20;46(1):75-87. doi: 10.1584/jpestics.D20-072
- Higo J, Takashima H, Fukunishi Y, Yoshimori A
Generalized-ensemble method study: A helix-mimetic compound inhibits protein-protein interaction by long-range and short-range intermolecular interactions.
J COMPUT CHEM. 2021 Mar 23. doi: 10.1002/jcc.26516
- Hayami T, Kamiya N, Kasahara K, Kawabata T, Kurita JI, Fukunishi Y, Nishimura Y, Nakamura H, Higo J
Difference of binding modes among three ligands to a receptor mSin3B corresponding to their inhibitory activities.
SCI REP. 2021 Mar 17;11(1):6178. doi: 10.1038/s41598-021-85612-9
- Yamamoto K, Honda T, Yokoyama S, Ma L, Kato A, Ito T, Ishizu Y, Kuzuya T, Nakamura M, Kawashima H, Ishigami M, Tsuji NM, Fujishiro M
Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine
Dig Liver Dis. 2021 Mar 13:S1590-8658(21)00081-5. doi: 10.1016/j.dld.2021.02.013
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Adipose-derived mesenchymal stem cells differentiate into heterogeneous cancer-associated fibroblasts in a stroma-rich xenograft model.
SCI REP. 2021 Feb 25;11(1):4690. doi: 10.1038/s41598-021-84058-3
- Kumagai Y, Hirasawa T, Wachi M
Requirement of the LtsA Protein for Formation of the Mycolic Acid-Containing Layer on the Cell Surface of Corynebacterium glutamicum.
MICROORGANISMS. 2021 Feb 16;9(2):409. doi: 10.3390/microorganisms9020409
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Coculture with hiPS-derived intestinal cells enhanced human hepatocyte functions in a pneumatic-pressure-driven two-organ microphysiological system
Sci Rep. 2021 Mar 8;11(1):5437. doi: 10.1038/s41598-021-84861-y
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LM-GlycomeAtlas Ver. 2.0: An Integrated Visualization for Lectin Microarray-based Mouse Tissue Glycome Mapping Data with Lectin Histochemistry.
J PROTEOME RES. 2021 Mar 4. doi: 10.1021/acs.jproteome.0c00907
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Alterations of protein glycosylation and DNA methylation in urothelial carcinoma.
CANCER SCIENCE 112 670-670; FEB
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Identification and Characterization of Mortaparib(Plus)-A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms.
CANCERS (Basel). 2021 Feb 17;13(4):835. doi: 10.3390/cancers13040835
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Cryptic-site binding mechanism of medium-sized Bcl-xL inhibiting compounds elucidated by McMD-based dynamic docking simulations.
SCI REP. 2021 Mar 3;11(1):5046. doi: 10.1038/s41598-021-84488-z
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Glycans on CEA as a targeting ligand of pancreatic ductal adenocarcinoma in novel lectin-drug conjugated therapy.
CANCER SCIENCE 112 718-718; FEB
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Establishment of G-quadruplex ligand-resistant cancer cells and elucidation of the resistance mechanism.
CANCER SCIENCE 112 558-558; FEB
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Complete Genome Sequence of Thiohalobacter sp. Strain COW1, Isolated from Activated Sludge Treating Coke Oven Wastewater.
MICROBIOL RESOUR ANNOUNC. 2021 Feb 18;10(7):e00013-21. doi: 10.1128/MRA.00013-21
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A novel methymycin analog, 12-ketomethymycin N-oxide, produced by the heterologous expression of the large pikromycin/methymycin biosynthetic gene cluster of Streptomyces sp. AM4900.
BIOSCI BIOTECHNOL BIOCHEM. 2020 Dec 22:zbaa111. doi: 10.1093/bbb/zbaa111
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GA-guided mD-VcMD: A genetic-algorithm-guided method for multi-dimensional virtual-system coupled molecular dynamics
Biophys Physicobiol. 2020 Dec 26;17:161-176. doi: 10.2142/biophysico.BSJ-2020008
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Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers.
BIOMOLECULES. 2021 Jan 26;11(2):160. doi: 10.3390/biom11020160
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Evaluation of intercellular cross-linking abilities correlated with cytotoxicities of bispecific antibodies with domain rearrangements using AFM force-sensing.
BIOSENS BIOELECTRON. 2021 Jan 27;178:113037. doi: 10.1016/j.bios.2021.113037
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Molecular dynamics simulations and experimental studies reveal differential permeability of withaferin-A and withanone across the model cell membrane.
SCI REP. 2021 Jan 27;11(1):2352. doi: 10.1038/s41598-021-81729-z
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Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy.
AUTOPHAGY. 2021 Jan 26:1-26. doi: 10.1080/15548627.2021.1874133
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An iPSC-based neural model of sialidosis uncovers glycolytic impairment-causing presynaptic dysfunction and deregulation of Ca(2+) dynamics
Neurobiol Dis. 2021 Jan 28:105279. doi: 10.1016/j.nbd.2021.105279
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Novel Pancreatic Cancer Therapy Targeting Cell Surface Glycans by Liposomes Modified with rBC2LCN Lectin
Eur Surg Res. 2021 Jan 27:1-10. doi: 10.1159/000513430
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Identification and characterization of the antigen recognized by the germ cell mAb TRA98 using a human comprehensive wet protein array
Genes Cells. 2021 Feb 1. doi: 10.1111/gtc.12832
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Membrane properties of amacrocyclic tetraether bisphosphatidylcholine lipid: Effect of a single membrane-spanning polymethylene cross-linkage between two head groups of ditetradecylphosphatidylcholine membrane.
BIOCHIM BIOPHYS ACTA BIOMEMBR. 2021 Feb 4:183569. doi: 10.1016/j.bbamem.2021.183569
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A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster.
J ANTIBIOT (Tokyo). 2021 Feb 8. doi: 10.1038/s41429-021-00410-9
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Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice.
PLOS ONE. 2021 Jan 19;16(1):e0245607. doi: 10.1371/journal.pone.0245607. eCollection
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Complete mitochondrial genome sequence of Japanese forest green tree frog (Rhacophorus arboreus.
Mitochondrial DNA B Resour 2020 Sep 16;5(3):3347-3348. doi: 10.1080/23802359.2020.1820396
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NATURE. 2021 Jan 6. doi: 10.1038/s41586-020-03113-7
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RSC ADVANCES 10 (71) 43319-43323; doi: 10.1039/d0ra09413g DEC 7
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CELL REP. 2021 Jan 5;34(1):108599. doi: 10.1016/j.celrep.2020.108599
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J PROTEOMICS. 2021 Jan 6:104098. doi: 10.1016/j.jprot.2020.104098
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FRONT GENET 2020 Nov 25;11:607812. doi: 10.3389/fgene.2020.607812. eCollection
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Platelet-derived extracellular vesicles are increased in sera of Alzheimers disease patients, as revealed by Tim4-based assays.
FEBS OPEN BIO 2020 Dec 20. doi: 10.1002/2211-5463.13068
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Molecular Interaction Mechanism of a 14-3-3 Protein with a Phosphorylated Peptide Elucidated by Enhanced Conformational Sampling.
J. Chem. Inf. Model 60 (10) 4867-4880; (2020) doi: 10.1021/acs.jcim.0c00551 OCT 26
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BIOMOLECULES. 2020 Dec 29;11(1):E32. doi: 10.3390/biom11010032
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Inhibition of HSP90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
CANCER SCI. 2020 Dec 28. doi: 10.1111/cas.14786
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Dermal fibroblast-like cells reprogrammed directly from adipocytes in mouse.
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Regulation of Fetal Genes by Transitions among RNA-Binding Proteins during Liver Development
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Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo.
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Salinity effects on the first larval stage of the invasive crab Hemigrapsus takanoi: Survival and swimming patterns
ESTUARINE COASTAL AND SHELF SCIENCE 245; (2020) doi: 10.1016/j.ecss.2020.106976
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Quantitative structural analysis of glycans expressed within tumors derived from pancreatic cancer patient-derived xenograft mouse models
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A Variable Scheduling Maintenance Culture Platform for Mammalian Cells
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Identification of Caffeic Acid Phenethyl Ester (CAPE) as a Potent Neurodifferentiating Natural Compound That Improves Cognitive and Physiological Functions in Animal Models of Neurodegenerative Diseases
Front Aging Neurosci. 2020 Nov 10;12:561925. doi: 10.3389/fnagi.2020.561925
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Membrane properties of ether-type phosphatidylcholine bearing partially fluorinated C(18)-monoacetylenic chains and their applicability to membrane protein reconstitution matrices
Colloids Surf B Biointerfaces. 2020 Nov 13:111459. doi: 10.1016/j.colsurfb.2020.111459
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Heterologous Expression of the Biosynthetic Gene Cluster for Verticilactam and Identification of Analogues
J Nat Prod. 2020 Nov 20. doi: 10.1021/acs.jnatprod.0c00755
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Interstitial flow regulates in vitro three-dimensional self-organized brain micro-vessels
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 533 (3) 600-606; (2020) doi:10.1016/j.bbrc.2020.09.061 DEC 10
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ARCH ORAL BIOL.121:104967 (2020) doi: 10.1016/j.archoralbio.2020.104967
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Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in Aged Interleukin-18 Deficient Mice
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Structural Fluctuations of Aromatic Residues in an Apo-Form Reveal Cryptic Binding Sites: Implications for Fragment-Based Drug Design
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Influence of Nivolumab for Intercellular Adhesion Force between a T Cell and a Cancer Cell Evaluated by AFM Force Spectroscopy
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Lectin Drug Conjugate Therapy for Colorectal Cancer
Cancer Sci. 2020 Oct 15. (2020) doi: 10.1111/cas.14687
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HETEROCYCLES 100 (2) 253-266; (2020) doi: 10.3987/COM-19-14191
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Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium
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Identification of a herpes simplex virus 1 gene encoding neurovirulence factor by chemical proteomics
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Screening siRNAs against host glycosylation pathways to develop novel antiviral agents against hepatitis B virus
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