Biotechnology Research Institute for Drug Discovery
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Research Groups

 
   AIST Tsukuba Central
   AIST Tokyo Waterfront

Glycoscience and Glycotechnology Research Group

Glycoscience & Glycotechnology Research Group develops a series of fundamental technologies for structural analysis, production, modification, detection, and information analysis of glycoproteins, aiming at application and uncovering of the relationship between glycan structures and functions and development of disease glycobiomarkers. Glycoscience and Glycotechnology Research Group

Stem Cell Engineering Research Group

We develop fundamental technology for regenerative medicine including "applications for quality control", "reliable differentiation methods" and "mass cultivation technology" using iPS/ES cells and mesenchymal stem cells. We aim to give back these results to society and to strengthen the related market. We validate the obtained knowledge macroscopically using model organisms and consolidate the background biological knowledge. Stem Cell Engineering Research Group
(Upper left) Live-staining of iPS cells by AiLecS1
(Upper right) Cilia cells derived from ES cells
(Lower left) Model organism, Xenopus laevis
(Lower right) Auto-culture equipment

Stem Cell Biotechnology Research Group

Stem cell biotechnology is important and fundamental in regenerative medicine, disease modeling, and drug discovery. Our stem cell biotechnology research is in a field of biotechnology that develops culture methods, devices, tools and therapeutics through modification and engineering of stem cells with fabrication of materials. Stem Cell Biotechnology Research Group

Drug Assay Device Research Group

Drug Assay Device Research Group aims to develop innovative cell-based assay technologies for screening of the pipeline compounds in drug discovery and medication prescription optimized for each patient, an application of personalized medicine. Assay Device Research Group

Leading-edge Biotechnology Research Group

The aim of our laboratory is the development of the wide-range of technologies such as the most advanced genome application, application of analytical instruments and informatics technology, which are applicable for the elucidation of life phenomena and production of industrial useful substances in microorganisms, plants and animals. Leading-edge Biotechnology Research Group

Cellular Glycome-targeted Technology Research Group

The Cellular Glycome-Targeted Technology Group develop the advanced glycan analysis technologies based on cellular glycomics principle and the glycan profiling technologies utilizing lectins focusing on the transition of the basic study toward industrial application in the fields of drug discovery and regenerative medicine. Cellular Glycome-targeted Technology Research Group
(Upper left) Lectin microarray
(Upper right) Lectin engineering
(Lower left) Supported Molecular Matrix Electrophoresis (SMME)
(Lower right) Newly developed peptide display technique (PERISS)

Research Laboratory for Human Cell Engineering

Normal human tissue cells are invaluable resource for modern medicine, such as regenerative medicine and gene therapy. However, availability of normal human cells suitable for medical application is limited. We are investigating basic science regarding human cell engineering, such as cell reprogramming and characterization. Research Laboratory for Human Cell Engineering



(Reorganized) Computational Regulatory Genomics Research Group

  →  Computational Omics Research Team, Artificial Intelligence Research Center


(Reorganized) Computational Functional Genomics Research Group

  →  Intelligent Bioinformatics Research Team, Artificial Intelligence Research Center


(Reorganized) Laboratory for Drug Discovery


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