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※ Genomic Neo-Function Research Group was reorganized as Leading-edge Biotechnology Research Group as of May 2, 2016.
Genomic Neo-Function Research Group

List of titles, authors, and journal information of published papers.

Publication

2015


Saccharothriolides A-C, novel phenyl-substituted 10-membered macrolides isolated from a rare actinomycete Saccharothrix sp
Lu S, Nishimura S, Hirai G, Ito M, Kawahara T, Izumikawa M, Sodeoka M, Shin-Ya K, Tsuchida T, Kakeya H
Chem Commun (Camb). 2015 May 11;51(38):8074-7
Substrate tRNA Recognition Mechanism of Eubacterial tRNA (m1A58) Methyltransferase (TrmI)
Takuma H, Ushio N, Minoji M, Kazayama A, Shigi N, Hirata A, Tomikawa C, Ochi A, Hori H
J Biol Chem. 2015 Feb 27;290(9):5912-25
Terpene synthases are widely distributed in bacteria
Yamada Y, Kuzuyama T, Komatsu M, Shin-Ya K, Omura S, Cane DE, Ikeda H
Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):857-62


2014


Biosynthesis of the 4-Methyloxazoline-Containing Nonribosomal Peptides, JBIR-34 and -35, in Streptomyces sp. Sp080513GE-23
Muliandi A, Katsuyama Y, Sone K, Izumikawa M, Moriya T, Hashimoto J, Kozone I, Takagi M, Shin-ya K, Ohnishi Y
Chem Biol. 2014 Aug 14;21(8):923-34


2013


Crystallographic and mutational studies on the tRNA thiouridine synthetase TtuA
Nakagawa H, Kuratani M, Goto-Ito S, Ito T, Katsura K, Terada T, Shirouzu M, Sekine S, Shigi N, Yokoyama S
Proteins. 2013 Jul;81(7):1232-44
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span
Watson LA, Solomon LA, Li JR, Jiang Y, Edwards M, Shin-ya K, Beier F, Bérubé NG
J Clin Invest. 2013 May;123(5):2049-63


2012


Relative Configuration of JBIR-129, a Cytotoxic 34-Membered Glycosidic Polyol Macrolide from Streptomyces sp. RK74
Kawahara T, Izumikawa M, Takagi M, Shin-ya K
Org Lett. 2012 Sep 7;14(17):4434-7
Posttranslational Modification of Cellular Proteins by a Ubiquitin-like Protein in Bacteria
Shigi N
J Biol Chem. 2012 May 18;287(21):17568-77


Review


Biosynthesis and functions of sulfur modifications in tRNA
Shigi N
Front Genet. 2014 Apr 2;5(67):1-11



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