機能性食品素材特別研究チーム
成果発表

    2019年

  1. S. Haga, Yimin, H. Yamaki, S. Jin, T. Sogon, N. Morita, M. Ozaki. Extracts of bilberry (Vaccinium myrtillus L.) fruits improve liver steatosis and injury in mice by preventing lipid accumulation and cell death. Biosci. Biotechnol. Biochem. in press.
  2. M. Makino, T. Sahara, N. Morita, H. Ueno. Carboxypeptidase Y activity and maintenance is modulated by a large helical structure. FEBS Open Bio 2019, 9, 1337-1343.
  3. S. Kato, H. Tobe, H. Matsubara, M. Sawada, Y. Sasaki, S. Fukiya, N. Morita, A. Yokota. The membrane phospholipid cardiolipin plays a pivotal role in bile acid adaptation by Lactobacillus gasseri JCM1131T. Biochim. Biophys. Acta 2019, 1864, 403-412.
  4. 2018年

  5. R. Yamamoto, H. Minami, H. Matsusaki, M. Sakashita, N. Morita, O. Nishimiya, N. Tsutsumi, M. Hosokawa, Y. Itabashi, T. Matsui, K. Ura. Consumption of the edible sea urchin Mesocentrotus nudus attenuates body weight gain and hepatic lipid accumulation in mice. J. Func. Foods 2018 47, 40-47.
  6. S. Haga, H. Kanno, T. Ozawa, N. Morita, M. Asano, M. Ozaki. Detection of necroptosis in ligand-mediated and hypoxia-induced injury of hepatocytes using a novel optic probe detecting receptor-interacting protein (RIP)1/RIP3 binding. Oncol. Res. 2018, 26, 503-513.
  7. S. Haga, T. Ozawa, N. Morita, M. Asano, S. Jin, Yimin, M. Ozaki. A photo-activatable Akt probe - A new tool to study Akt-dependent physio-pathology of cancer cells. Oncol. Res. 2018, 26, 467-472
  8. 2017年

  9. T. Adachi, T. Sahara, H. Okuyama, N. Morita. Glass bead-based genetic transformation: An efficient method for transformation of thraustochytrid microorganisms. J. Oleo Sci. 2017, 66, 791-795.
  10. 2016年

  11. N. Morita, S. Haga, Y. Ohmiya, M. Ozaki. Long-term ex vivo and in vivo monitoring of tumor progression by using dual luciferases. Anal. Biochem. 2016, 497, 24-26.
  12. K. Yoshida, M. Hashimoto, R. Hori, T. Adachi, H. Okuyama, Y. Orikasa, T. Nagamine, S. Shimizu, A. Ueno, N. Morita. Bacterial long-chain polyunsaturated fatty acids: Their biosynthetic genes, functions, and practical use. Marine Drugs 2016, 14, 94.
  13. T. Okuda, N. Morita. A very low carbohydrate ketogenic diet increases hepatic glycosphingolipids related to regulation of insulin signaling. J. Func. Foods 2016, 21, 70-74.
  14. 2015年

  15. M. Kanno, T. Katayama, N. Morita, H. Tamaki, S. Hanada, Y. Kamagata. Catenisphaera adipatacumulans gen. nov., sp. nov., a member of the family Erysipelotrichaceae isolated from an anaerobic digester. Int. J. Syst. Evol. Microbiol. 2015, 65, 805-810.
  16. 2014年

  17. S. Haga, T. Ozawa, Y. Yamada, N. Morita, I. Nagashima, H. Inoue, Y. Inaba, N. Noda, R. Abe, K. Umezawa, M. Ozaki. p62/SQSTM1 plays a protective role in oxidative injury of steatotic liver in a mouse hepatectomy model. Antioxid. Redox Signal. 2014, 21, 2515-2530, 2014.
  18. T. B. Narita, T. W. Kikukawa, Y. G. Sato, S. H. Miyazaki, N. Morita, T. Saito. Role of fatty acid synthase on the development of Dictyostelium discoideum. J. Oleo Sci. 2014, 63, 281-289
  19. T. Katayama, M. Kanno, N. Morita, T. Hori, T. Narihiro, Y. Mitani, Y. Kamagata. An oleaginous bacterium that intrinsically accumulates long-chain free fatty acids in its cytoplasm. Appl. Environ. Microbiol. 2014, 80, 1126-1131.
  20. M. Makino, T. Sahara, N. Morita, H. Ueno. Amino acid substitution reveals the role of V-shape helix on construction of yeast carboxypeptidase Y. J. Biol. Macromol. 2014, 14, 27-41.
  21. 2013年

  22. M. Kanno, T. Katayama, H. Tamaki, Y. Mitani, X.-Y. Meng, T. Hori, T. Narihiro, N. Morita, T. Hoshino, I. Yumoto, N. Kimura, S. Hanada, Y. Kamagata. Isolation of butanol- and isobutanol-tolerant bacteria and physiological characterization of their butanol tolerance. Appl. Environ. Microbiol. 2013, 79, 6998-7005.
  23. T. Okuda, A. Fukui, N. Morita. Altered expression of O-GlcNAc-modified proteins in a mouse model whose glycemic status is controlled by a low carbohydrate ketogenic diet. Glycoconj. J. 2013, 30, 781-789.
  24. S. Sato, N. Morita, D. Kitamoto, H. Habe. Expression and characterization of a class III alcohol dehydrogenase gene from Gluconobacter frateurii in the presence of methanol during glyceric acid production from glycerol. J. Oleo Sci. 2013, 62, 835-842.
  25. T. Morita, D. Kawamura, N. Morita, T. Fukuoka, T. Imura, H. Sakai, M. Abe, D. Kitamoto. Characterization of mannosylerythritol lipids including hexadecatetraenoic acid produced from cuttlefish oil by Pseudozyma churashimaensis OK96. J. Oleo Sci. 2013, 62, 319-327
  26. S. Sato, N. Morita, D. Kitamoto, T. Yakushi, K. Matsushita, H. Habe. Change in product selectivity during the production of glyceric acid from glycerol by Gluconobacter strains in the presence of methanol. AMB Express 2013, 3, 20.
  27. T. Shiraishi, S.-I. Yokota, N. Morita, S. Fukiya, T. Tomita, N. Tanaka, S. Okada, A. Yokota. Characterization of lipoteichoic acid from Lactobacillus gasseri JCM 1131T: A novel glycolipid anchor structure. Appl. Environ. Microbiol. 2013, 79, 3315-3318.
  28. K. Hirota, K. Aino, Y. Nodasaka, N. Morita, I. Yumoto. Amphibacillus indicireducens sp. nov., a facultatively alkaliphile that reduces an indigo dye. Int. J. Syst. Evol. Microbiol. 2013, 63, 464-469.

    総説、成書、和文誌

  1. 森田直樹(2014):農林水産物・食品の機能性評価 ~ 核内受容体を利用して評価する ~. グリーンテクノ情報 10, 6-10.
  2. 尾崎倫孝、芳賀早苗、森田直樹、野田なつみ、小澤岳昌(2014):光学技術を応用した新たな臓器保存法,細胞・臓器移植法の開発. Organ Biology 21, 171-176.
  3. 坂下真実、西宮佳志、近藤英昌、津田栄、山脇浩、藤久裕司、後藤義人(2014):高圧下における魚類由来不凍タンパク質と氷の相互作用. Photon Factory Activity Report 2013 #31B, 197.
  4. 坂下真実、西宮佳志、近藤英昌、津田栄、山脇浩、藤久裕司、後藤義人(2013):魚類由来III型不凍タンパク質水溶液における圧力効果. Photon Factory Activity Report 2012 #30B, 253.

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生物プロセス研究部門

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