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  • 2017N

    1. Tomita S., Ishihara S., Kurita R.
      A Multi-Fluorescent DNA/Graphene Oxide Conjugate Sensor for Signature-Based Protein Discrimination.
      Sensors, 17, 2194 (2017).
    2. Tomita S., Matsuda A., Nishinami S.,Kurita R., Shiraki K.
      One-step identification of antibody degradation pathways using fluorescence signatures generated by cross-reactive DNA-based arrays.
      Anal. Chem., 89, 7818-7822 (2017).
    3. Kurinomaru T., Kojima N., Kurita R.
      An alkylating immobilization linker for immunochemical epigenetic assessment .
      Chem. Commun., 53, 8308-8311 (2017).
    4. Kurinomaru T., Kuwada K., Tomita S., Kameda T., Shiraki K.
      Noncovalent PEGylation Through Protein-Polyelectrolyte Interaction: Kinetic Experiment and Molecular Dynamics Simulation.
      J. Phys. Chem. B, 121, 6785-6791 (2017).
    5. Tomita S., Ishihara S., Kurita R.
      Environment-Sensitive Turn-On Fluorescent Polyamino Acid: Fingerprinting Protein Populations with Post-Translational Modifications.
      ACS Appl. Mater. Interfaces, 9, 22970-22976 (2017).
    6. Kurita R., Yanagisawa H., Kamata T., Kato D., Niwa O.
      On-Chip Evaluation of DNA Methylation with Electrochemical Combined Bisulfite Restriction Analysis Utilizing a Carbon Film Containing a Nanocrystalline Structure.
      Anal. Chem., 89, 5976-5982 (2017).
    7. Onishi Y. Tomita T., Kurita R.
      Epigenetic regulation of the circadian clock: Role of 5-aza-2'-deoxycytidine.
      Biosci. Rep., 37, BSR20170053 (2017).
    8. Kurinomaru T., Kurita R.
      Bisulfite-free approaches for DNA methylation profiling.
      Anal. Methods, 9, 1537-1549 (2017).



    2016
    N

    1. Kowata K, Kojima N, Komatsu Y
      Development of a 3f-amino linker with high conjugation activity and its application to conveniently cross-link blunt ends of a duplex.
      Bioorg. Med. Chem., 24, 2108-2113 (2016).
    2. Kunitake M., Kuraya E., Kato D., Niwa O., Nishimi T.
      Electrochemistry in bicontinuous microemulsions based on control of dynamic solution structures on electrode surfaces.
      Curr. Opin. Colloid Interface Sci., 25, 13-26 (2016).
    3. Shiba S., Yoshioka K., Kato D., Ishihara S., Anzai H., Saito N., Niwa O.
      Electrochemical microfluidic devices for evaluation of drug metabolism.
      J. Electroanal. Chem., 779, 86-91 (2016).
    4. Shiba S., Kato D., Kamata T., Niwa O.
      Co-sputter deposited nickel-copper bimetallic nanoalloy embedded carbon films for electrocatalytic biomarker detection.
      Nanoscale, 8, 12887-12891 (2016).
    5. Furuhata Y, Kikuchi Y, Tomita S, Yoshimoto K
      Small spheroids of adipose-derived stem cells with time-dependent enhancement of IL-8 and VEGF-A secretion.
      Genes Cells, 21, 1380-1386 (2016)
    6. Tomita S, Niwa O, Kurita R
      Artificial modification of an enzyme for construction of cross-reactive polyion complexes to fingerprint signatures of proteins and mammalian cells.
      Anal. Chem., 88, 9079-9086 (2016)
    7. Kurwada K, Kurinomaru T, Tomita S, Shiraki K
      Noncovalent PEGylation-based enzyme switch in physiological saline conditions using quaternization polyamines.
      Colloid Polym. Sci., 294, 1551-1556 (2016)
    8. Iwasaki W., Sathuluri R., Kurita R., Niwa O., Miyazaki M.
      Effects of Electrode Placement and Measurement Time on Electrochemical Signal of Redox Species Flowing through Porous Material.
      Sens. Mater., 28, 1329-1335 (2016).
    9. Minamiki T., Minami T., Sasaki Y., Wakida S., Kurita R., Niwa O., Tokito S.
      Label-Free Detection of Human Glycoprotein (CgA) Using an Extended-Gated Organic Transistor-Based Immunosensor.
      Sensors, 16, 2033 (2016).
    10. Kurita R, Niwa O
      Microfluidic platforms for DNA methylation analysis.
      Lab chip, 16, 3631-3644 (2016).
    11. Minami T, Sasaki Y, Minamiki T, Wakida S, Kurita R, Niwa O, Tokito S.
      Selective nitrate detection by an enzymatic sensor based on an extended-gate type organic field-effect transistor.
      Biosens. Bioelectron., 81, 87-91 (2016).
    12. Oda A, Kato D, Yoshioka K, Tanaka M, Kamata T, Todokoro M, Niwa O
      Fluorinated nanocarbon film electrode capable of signal amplification for lipopolysaccharide detection.
      Electrochim. Acta, 197, 152-158 (2016).
    13. Kato D, Kamata T, Kato D, Yanagisawa H, Niwa O
      Au nanoparticle-embedded carbon films for electrochemical As3+ detection with high sensitivity and stability.
      Anal. Chem., 88(5), 2944-2951 (2016).
    14. Kuraya E, Nagatomo S, Sakata K, Kato D, Niwa O, Nishimi T, Kunitake M Direct analysis of lipophilic antioxidants of olive oils using bicontinuous microemulsions.
      Anal. Chem., 88(2), 1202-1209 (2016).
    15. Tomita S, Yokoyama S, Kurita R, Niwa O, Yoshimoto K
      The use of an enzyme-based sensor array to fingerprint proteomic signatures of sera from different mammalian species.
      Anal. Sci., 32(2), 237-240 (2016).
    16. Shiraki K, Kurinomaru T, Tomita S
      Wrap-and-strip technology of protein-polyelectrolyte complex for biomedical application.
      Curr. Med. Chem., 23(3), 276-289 (2016).
    17. Shiraki K, Tomita S, Inoue N
      Small amine molecules: Solvent design toward facile improvement of protein stability against aggregation and inactivation.
      Curr. Pharm. Biotechnol., 17, 116-125 (2016).

     

    2015N

    1. Kurita, R., Yanagisawa, H., Yoshioka, K., Niwa, O.: On-chip sequence-specific immunochemical epigenomic analysis utilizing outward turned cytosine in a DNA bulge with handheld surface plasmon resonance equipment. Anal. Chem., 87(22), 11581-11586 (2015).
    2. Tomita, S., Sakao, M., Kurita, R., Niwa, O., Yoshimoto, K.: A polyion complex sensor array for markerless and noninvasive identification of differentiated mesenchymal stem cells from human adipose tissue. Chem. Sci., 6(10), 5831-5836 (2015).
    3. Yanagisawa, H., Kurita, R., Yoshida, T., Kamata, T., Niwa, O.: Electrochemical assessment of local cytosine methylation in genomic DNA on a nanocarbon film electrode fabricated by unbalanced magnetron sputtering. Sens. Actuator B-Chem., 221, 816-822 (2015).
    4. Minamiki, T., Minami, T., Sasaki, Y., Kurita, R., Niwa, O., Wakida, S., Tokito, S.: An organic field-effect transistor with an extended-gate electrode capable of detecting human immunoglobulin A. Anal. Sci., 31(7), 725-728 (2015).
    5. Yanagisawa, H., Kurita, R., Kamata, T., Yoshioka, K., Kato, D., Iwasawa, A., Nakazato, T., Torimura, M., Niwa, O.: Effect of sp2/sp3 ratio in a hybrid nanocarbon thin film electrode for anodic strip-ping voltammetry fabricated by unbalanced magnetron sputtering equipment. Anal. Sci., 31(7), 635-641 (2015).
    6. Kamata, T., Kato, D., Umemura, S., Niwa, O.: Structure and electroanalytical application of nitrogen-doped carbon thin film electrode with lower nitrogen concentrations. Anal. Sci., 31(7), 651-656 (2015).
    7. Shiba, S., Inoue, J., Kato, D., Yoshioka, K., Niwa, O.: Graphene modified electrode for the direct electron transfer of bilirubin oxidase. Electrochemistry, 83(5), 332-334 (2015).
    8. Kurita, R., Yanagisawa, H., Yoshioka, K., Niwa, O.: Site-specific immunochemical methylation assessment from genome DNA utilizing a conformational difference between looped-out target and stacked-in nontarget methylcytosines. Biosens. Bioelectron., 70, 366-371 (2015).
    9. Kuraya, E., Nagatomo, S., Sakata, K., Kato, D., Niwa, O., Nishimi, T., Kunitake, M.: Direct analysis of lipophilic antioxidants of olive oils using bicontinuous microemulsions. Anal. Chem., 88(2), 1202-1209 (2015).
    10. Kuraya, E., Nagatomo, S., Sakata, K., Kato, D., Niwa,O., Nishimi,T., Kunitake, M.: Simultaneous electrochemical analysis of hydrophilic and lipophilic antioxidants in bicontinuous microemulsion. Anal. Chem., 87(3), 1489-1493 (2015).

     

    2014N

    1. Tomita, S., Soejima, T., Shiraki, K., Yoshimoto, K.: Enzymatic fingerprinting of structurally similar homologous proteins using polyion complex library constructed by tuning PEGylated polyamine functionalities. Analyst, 139(23), 6100-6103 (2014).
    2. Yanagisawa, H., Kurita, R., Kamata, T., Kato, D., Niwa, O.: Anodic stripping voltammetric determination of Cd and Pb with nanocarbon film electrode fabricated by unbalanced magnetron sputtering. Electrochemistry, 82(11), 949-953 (2014).
    3. Kamata,T., Katoa, D., Ida, H., Niwa, O. : Structure and electrochemical characterization of carbon films formed by unbalanced magnetron (UBM) sputtering method. Diam. Relat. Mat., 49, 25-32 (2014).
    4. Sato, Y., Yoshioka, K., Murakami, T., Tanaka, M., Niwa, O.: Thick-matrix-free interface for highly effective protein detection and sufficient signal enhancement. Compos. Interfaces, 21(7), 631-638 (2014).
    5. Guo, Q., Liu, D., Zhang, X., Li, L., Hou, H., Niwa, O., You, T. : Pd-Ni alloy nanoparticle/carbon nanofiber composites: preparation, structure, and superior electrocatalytic properties for sugar analysis. Anal. Chem. , 86(12), 5898-5905 (2014).
    6. Yosioka, K., Kato, D., Kamata, T., Niwa, O.: High performance of DET-type bioelectrocatalysis of cytochrome c on indium tin oxide film electrode with enzyme-sized nanostructure. Electrochemistry, 82(5), 322-324 (2014).
    7. Liu, D., Guo, Q., Hou, H., Niwa, O., and You, T. : PdxCoy nanoparticle/carbon nanofiber composites with enhanced electrocatalytic properties. ACS Catal., 4(6), 1825-1829(2014).
    8. Kato, D., Oda, A., Tanaka, M., Iijima, S., Kamata, T., Todokoro, M., Yoshimi, Y., Niwa, O.: Poly--Lysine Modified Nanocarbon Film Electrodes for LPS Detection. Electroanalysis, 26, 618-624 (2014).

     

    2013N

    1. Yosioka K., Kato D., Kamata T., Niwa O.: Cytochrome P450 modified polycrystalline indium tin oxide film as a drug metabolizing electrochemical biosensor with a simple conifiguration. Anal. Chem., 85, 9996-9999(2013).
    2. Kamata T., Kato D., Hirono S., Niwa O.: Structure and electrochemical performance of nitrogen-doped carbon film formed by electron cyclotron resonance sputtering. Anal. Chem., 85, 9845-9851 (2013).
    3. Xue Q., Kato D., Kamata T., Guo Q., You T., Niwa O.: Human cytochrome P450 3A4 and carbon nanofiber modified film electrode as a platform for the simple evaluation of drug metabolism and inhibition reactions. Analyst, 138, 6463-6468 (2013).
    4. Xue Q., Kato D., Kamata T., Guo Q., You T., Niwa O.: Improved direct electrochemistry for proteins adsorbed on UV/ozone treated carbon nanofiber electrode. Anal. Sci., 29, 611-618 (2013).
    5. Kurita, R., Yanagisawa, H., Niwa, O.: Indoor allergen assessment quantified by a thin-layer electrochemical cell and magnetic beads. Biosens. Bioelectron. (2013).
    6. Yamamura, T., Hoshikawa, M., Kato, D., Saito, H., Suzuki, N., Niwa, O., Okada, M.: ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation. Br. J. Pharmacol., 168, 1088-1100 (2013).

     

    2012N

    1. Kamata, T., Niwa, O., Umemura, S., Hirono, S.:The structure and bonding state for fullerene-like carbon nitride films with high hardness formed by electron cyclotron resonance plasma sputtering. Jpn. J. Appl. Phys., 51(12), 125602-1-125602-10 (2012).
    2. Kato, D., Sumimoto, M., Ueda, A., Hirono, S., Niwa, O.: Evaluation of electrokinetic parameters for all DNA bases with sputter deposited nanocarbon film electrode. Anal. Chem., 84(24), 10607-10613 (2012).
    3. Xue, Q., Kato, D., Kamata, T., Umemura, S., Hirono, S., Niwa, O.: Electrochemical properties and biomolecule adsorption at ECR-sputtered nanocarbon film electrode compared with DLC and GC electrodes. Jpn. J. Appl. Phys., 51 (2012).
    4. Kurita, R., Niwa, O.: DNA methylation analysis triggered by bulge specific immuno-recognition. Anal. Chem., 84, 7533-7538 (2012).
    5. Yamamura, T., Hoshikawa, M., Kato, D., Saitou, H., Suzuki, N., Niwa, O., Okada, M.: ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation. Br. J. Pharmacol. (2012).
    6. Chen, Y., Nakamoto, K., Niwa, O., Corn, R.M.: On-chip synthesis of RNA aptamer microarray for multiplexed protein biosensing with SPRmeasurements. Langmuir, 28, 8281-8285 (2012).
    7. Nakamoto, K., Kurita, R., Niwa, O.: Electrochemical surface plasmon resonance measurement based on gold nanohole array fabricated by nanoimprinting technique. Anal. Chem., 84, 3187-3191 (2012).
    8. Sato, Y., Yoshioka, K., Murakami, T., Yoshimoto, S., Niwa, O.: Design of biomolecular interface for detecting carbohydrate and lectin weak interactions. Langmuir, 28(3), 1846-1851 (2012).
    9. Kurita, R., Arai, K., Nakamoto, K., Kato, D., Niwa, O.: Determination of DNA methylation using electrochemiluminescence with surface accumulable coreactant. Anal. Chem., 84(4), 1799-1803 (2012).
    10. Kurita, R., Nakamoto, K., Sato, Y., Kamata, T., Ueda, A., Kato, D., Hirono, S., Niwa, O.: An sp2 and sp3 hybrid nanocrystalline carbon film electrode for anodic stripping voltammetry and its application for electrochemical immunoassay. Anal. Sci., 28(1), 13-20 (2012).

     

    2011N

    1. Nakamoto, K., Kurita, R., Niwa, O., Fujii, T., Nishida, M.: Development of a mass-reproducible on-chip plasmonicnanohole array biosensor. Nanoscale, 3, 5067-5075 (2011).
    2. Kato, D., Goto, K., Fujii, S., Takatsu, A., Hirono, S., Niwa, O.: Electrochemical DNA methylation detection for enzymatically digested CpG oligonucleotides. Anal. Chem., 83(20), 7595-7599 (2011).
    3. Kato, D., Komoriya, M., Nakamoto, K., Kurita, R., Hirono, S., Niwa, O.: Electrochemical determination of oxidative damaged DNA with high sensitivity and stability using a nanocarbon film . Anal. Sci., 27(7), 703-707 (2011).
    4. Kamisaka, Y., Goto, R., Shibakami, M., Yoshioka, K., Sato, Y.: Surface plasmon resonance analysis of interactions between diacylglycerol acyltransferase and its interacting factors. Biosci. Biotechnol. Biochem., 75(6), 1135-1139 (2011).
    5. Nishimura, T., Sato, Y., Tanaka, M., Kurita, R., Nakamoto, K., Niwa, O.: Bifunctional tri(ethylene glycol) alkanethiol monolayer modified gold electrode for on chip electrochemical immunoassay of pg level leptin. Anal. Sci., 27(5), 465-469 (2011).
    6. Inokuchi, H., Kato, D., Ueda, A., Niwa, O.: Development of sputtered nanocarbon film based microdisk array electrode for the highly stable detection of serotonin. Electroanalysis, 23(4), 827-831 (2011).
    7. Ueda, A., Kato, D., Kurita, R., Kamata, T., Inokuchi, H., Umemura, S., Hirono, S., Niwa, O.: Efficient direct electron transfer with enzyme on a nanostructured carbon film fabricated with a maskless top-down uv/ozone process. J. Am. Chem. Soc., 133, 4840-4846 (2011).

     

    2010N

    1. Nakamoto, K., Kurita, R., Niwa, O.: One-chip biosensor for simultaneous disease marker/calibration substance measurement in human urine by electrochemical surface plasmon resonance method. Biosens. Bioelectron., 26, 1536-1542 (2010).
    2. Goto, K., Kato, D., Sekioka, N., Ueda, A., Hirono, S., Niwa, O.: Direct electrochemical detection of DNA methylation for retinoblastoma and CpG fragments using a nanocarbon film. Anal. Biochem., 405, 59-66 (2010).
    3. Kurita, R., Arai, K., Nakamoto, K., Kato, D., Niwa, O.: Development of electrogenerated chemiluminescience-based enzyme linked immunosorbent assay for sub-pM detection. Anal. Chem., 82(5), 1692-1697 (2010).
    4. Yoshioka, K., Sato, Y., Tanaka, M., Murakami, T., Niwa, O.: Suppression of non-specific adsorption using densified tri(ethylene glycol) alkanethiols: monolayer characteristics evaluated by electrochemical measurements. Anal. Sci., 26, 33-37 (2010).
    5. Yoshioka, K., Sato, Y., Murakami, T., Tanaka, M., Niwa, O.: One-step detection of galectins on hybrid monolayer surface with protruding lactoside. Anal. Chem. 82(4), 1175-1178 (2010).

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