"Exposure and risk assessment of 1,3-butadiene in Japan" 

Haruyuki Higashino

National Institute of Advanced Industrial Science and Technology 

International Symposium of Evaluation of Butadiene and Chloroprene Health Risks (Charleston, South Carolina USA 2005/9/20)

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Abstract

We assessed the risks and consequences of exposure to 1,3-butadiene on human health. A remarkable advantage of our risk assessment approach is the detailed assessment of exposure. Previously, we developed two different models that can be applied for the assessment of exposure: the first, the AIST-ADMER model estimates regional concentration distributions, whereas the second, the METI-LIS model estimates concentration distributions in the vicinity of factories. Both models were used for the assessment of exposure to 1,3-butadiene. Using exposure concentration and cancer unit risk-related data, we evaluated the excess lifetime cancer risk for persons exposed to 1,3-butadiene over the course of a lifetime. 

Keywords

1,3-butadiene; Exposure assessment; Risk assessment; Human health; Japan