AIST
> Biomedicinal Information Research Center / English
Japanese
Concept
Greetings from Director
Member
Protein Structural Information
Analysis Team
Outline of research
Mission
Research results
Biological Systems Control
Team
Outline of research
Mission
Research results
Functional Rnomics Team
Outline of research
Mission
Research results
Integrated Database and
Systems Biology Team
Outline of research
Mission
Research results
Diagnosis and Prevention for
Mycoplasma-linked diseases
What's new
Access map
Site map
LINK
Contact
Aomi 2-4-7, Koto-ku,
Tokyo 135-0064, JAPAN
Biomedicinal Information Research Center (BIRC)
Tel
：+81-3-3599-8102
FAX
：+81-3-3599-2064
mail
：birc_webmaster_e@m.aist.go.jp
Fundamental Technologies for Drug Discovery
in the Post-Genomic Era
2010.07.30
Other researches
" Diagnosis and Prevention for Mycoplasma-linked diseases"
Update
2010.07.26
Member
Update
2010.05.27
[ Press release ]
Cross search of life-science databases supported by MEXT and METI was realized.
2010.05.25
Member
Update
2009.06.26
[ Press release ]
Efficient oligonucleotide-mediated degradation of nuclear noncoding RNAs in mammalian cultured cells
This study was supported by "Functional RNA Project" (2004-2008), which was subsidized by New Energy and Industrial Technology Development Organization (NEDO).
Details are available online at the website of
RNA
published by the RNA sosiety (
Abstract is here
).
2009.06.09
The link to
Human Gene and Protein Database (HGPD)
opened. (Biological Systems Control Team)
2009.04.10
Member
Update
2009.02.19
Member
Update
2009.01.28
[ Press release ]
MENε/β noncoding RNAs are essential for structural integrity of nuclear paraspeckles
This study was supported by "Functional RNA Project" (2004-2008), which was subsidized by New Energy and Industrial Technology Development Organization (NEDO).
Details were published online at the website of The Proceedings of the
National Academy of Sciences of the United States of America
(
Abstract is here
).
2009.01.28
Member
Update
2008.12.11
Site open
2008.11.25
[ Press release ]
Distribution of clones to research community launched from world's largest human cDNA library for protein expression, expected to accelerate post-genome sequence research.
BIRC has constructed world's largest, high-quality resource to express human proteins in collaboration with NEDO, JBIC and NITE, and started to distribute the clones to the research community.
For details of this resource, please see our article published in the December issue of
Nature Methods (vol. 5, pp.1011-1017; DOI:10.1038/NMETH.1273)
.
Concept
BIRC aims to promote obtaining archiving and integrating biological knowledge derived from massive genome analyses.
Emphases are laid on areas in which Japan is leading other countries, including tertiary structure analysis of membrane proteins, functional analysis of human full-length cDNAs, ncRNA, chemical biology and bioinformatics.
Greeting from Director
Biomedicinal Information Research Center
Director Dr. Ichio Shimada
The Biomedicinal Information Research Center( BIRC ) has been established in April 2008 in Tokyo Bay Area as a successor institution of Biological Information Research Center.
BIRC is a core place of post-genomic research, analyzing structure and function of gene products, such as proteins, and developing fundamental technologies of drug discovery.
BIRC focuses on post-genome- sequence research, such as analysis of protein-protein interactions using human full-length cDNAs, structural analysis of membrane protein which is the main target in drug discovery, studies of bio-active compounds by means of computational science and using microbial metabolites, to achieve ultimate goal of developing fundamental technologies of drug discovery.
Functional analysis of non-coding RNA is a new research area which is to introduce a paradigm for biomedicinal research field.
Integrated database is compiling annotation data of human full-length cDNAs and the results of interaction studies, and contributes to the life science research by publicizing information on the web.
BIRC will promote strategic joint-research project reflecting industrial needs under collaboration with government, industry, and academia.
Member
Official position
Name
Director
Dr. Ichio Shimada
Deputy Director
Dr. Taro Uyeda
Deputy Director
Dr. Junichi Sugai
Special Counselor
Dr. Takashi Gojobori
Invited Senior Research Scientist
Dr. Kazuhiro Matsuda
Invited Senior Research Scientist
Dr. Koji Ichiyama
Research Administration
Yuichi Yamaguchi
Protein Structural Information Analysis Team
Team Leader
Dr. Kaoru Mitsuoka
Senior Research Scientist
Dr. Toshiya Senda
Senior Research Scientist
Dr. Kazuhiro Mio
Research Scientist
Dr. Koh Takeuchi
Senior Research Scientist
Dr. Yoshifumi Fukunishi
Invited Senior Research Scientist
Dr. Fujiyoshi Yoshinori
Invited Senior Research Scientist
Dr. Haruki Nakamura
Biological Systems Control Team
Team Leader
Dr. Toru Natsume
Senior Research Scientist
Dr. Shunichiro Iemura
Senior Research Scientist
Dr. Naoki Goshima
Senior Research Scientist
Dr. Kazuo Shinya
Functional RNomics Team
Team Leader
Dr. Tetsuro Hirose
Research Scientist
Dr. Naoki Shigi
Integrated Database and Systems Biology Team
Team Leader
Dr. Tadashi Imanishi
Copyright(c) 2008-2010 BIRC, National Institute of Advanced Industrial Science and Technology (AIST) . All rights reserved.
